CL2024002031A1 - Materiales y métodos de las proteínas de unión a il-1beta. - Google Patents

Materiales y métodos de las proteínas de unión a il-1beta.

Info

Publication number
CL2024002031A1
CL2024002031A1 CL2024002031A CL2024002031A CL2024002031A1 CL 2024002031 A1 CL2024002031 A1 CL 2024002031A1 CL 2024002031 A CL2024002031 A CL 2024002031A CL 2024002031 A CL2024002031 A CL 2024002031A CL 2024002031 A1 CL2024002031 A1 CL 2024002031A1
Authority
CL
Chile
Prior art keywords
methods
materials
binding proteins
1beta binding
1beta
Prior art date
Application number
CL2024002031A
Other languages
English (en)
Spanish (es)
Inventor
Pascual Gabriel
Hindi Sagit
Kumar Swaminathan Suresh
J Edwards Matthew
Scott Stevenson Christopher
Original Assignee
Johnson & Johnson Entpr Innovation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Entpr Innovation Inc filed Critical Johnson & Johnson Entpr Innovation Inc
Publication of CL2024002031A1 publication Critical patent/CL2024002031A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CL2024002031A 2022-01-07 2024-07-03 Materiales y métodos de las proteínas de unión a il-1beta. CL2024002031A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202263297436P 2022-01-07 2022-01-07

Publications (1)

Publication Number Publication Date
CL2024002031A1 true CL2024002031A1 (es) 2024-12-20

Family

ID=84981504

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2024002031A CL2024002031A1 (es) 2022-01-07 2024-07-03 Materiales y métodos de las proteínas de unión a il-1beta.

Country Status (18)

Country Link
US (1) US20230227545A1 (https=)
EP (1) EP4460517A1 (https=)
JP (1) JP2025504383A (https=)
KR (1) KR20240130138A (https=)
CN (1) CN118974083A (https=)
AR (1) AR128222A1 (https=)
AU (1) AU2023206045A1 (https=)
CA (1) CA3247125A1 (https=)
CL (1) CL2024002031A1 (https=)
CO (1) CO2024009735A2 (https=)
DO (1) DOP2024000129A (https=)
IL (1) IL314129A (https=)
JO (1) JOP20240153A1 (https=)
MX (1) MX2024008553A (https=)
PE (1) PE20242347A1 (https=)
TW (1) TW202337904A (https=)
UY (1) UY40097A (https=)
WO (1) WO2023131901A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025186317A1 (en) * 2024-03-06 2025-09-12 Elanco Us Inc. Veterinary compositions of modified virus-like particles of cmv and canine il-1beta mutein antigens

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CN115362470A (zh) 2020-01-17 2022-11-18 强生企业创新公司 用于预测未来肺癌的风险的系统和方法

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