CL2022003743A1 - Formulaciones de tableta dispersable que comprenden dolutegravir - Google Patents
Formulaciones de tableta dispersable que comprenden dolutegravirInfo
- Publication number
- CL2022003743A1 CL2022003743A1 CL2022003743A CL2022003743A CL2022003743A1 CL 2022003743 A1 CL2022003743 A1 CL 2022003743A1 CL 2022003743 A CL2022003743 A CL 2022003743A CL 2022003743 A CL2022003743 A CL 2022003743A CL 2022003743 A1 CL2022003743 A1 CL 2022003743A1
- Authority
- CL
- Chile
- Prior art keywords
- dolutegravir
- dispersible tablet
- tablet formulations
- formulations
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a formulaciones que comprenden dolutegravir o una sal farmacéuticamente aceptable del mismo, procesos para elaborar estas formulaciones y el uso de estas formulaciones en el tratamiento de la infección por VIH, en particular en el tratamiento de la infección por VIH en pacientes pediátricos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB2009684.8A GB202009684D0 (en) | 2020-06-26 | 2020-06-26 | Formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2022003743A1 true CL2022003743A1 (es) | 2023-06-30 |
Family
ID=71949817
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2022003743A CL2022003743A1 (es) | 2020-06-26 | 2022-12-23 | Formulaciones de tableta dispersable que comprenden dolutegravir |
Country Status (15)
Country | Link |
---|---|
US (1) | US20230285307A1 (es) |
EP (1) | EP4171572A1 (es) |
JP (1) | JP2023531086A (es) |
KR (1) | KR20230028288A (es) |
CN (1) | CN115697344A (es) |
AR (1) | AR122718A1 (es) |
AU (1) | AU2021296506A1 (es) |
BR (1) | BR112022026243A2 (es) |
CA (1) | CA3180544A1 (es) |
CL (1) | CL2022003743A1 (es) |
GB (1) | GB202009684D0 (es) |
IL (1) | IL298353A (es) |
MX (1) | MX2022015438A (es) |
TW (1) | TW202216154A (es) |
WO (1) | WO2021260567A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114191404B (zh) * | 2022-01-10 | 2023-06-27 | 安徽贝克生物制药有限公司 | 一种多替拉韦片剂及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014125124A1 (en) * | 2013-02-18 | 2014-08-21 | Ratiopharm Gmbh | Solid pharmaceutical dosage form of dolutegravir |
WO2014184553A1 (en) * | 2013-05-15 | 2014-11-20 | Cipla Limited | Pharmaceutical antiretroviral compositions |
WO2015140569A1 (en) * | 2014-03-20 | 2015-09-24 | Cipla Limited | Pharmaceutical composition |
WO2016125192A2 (en) * | 2015-02-06 | 2016-08-11 | Mylan Laboratories Limited | Process for the preparation of dolutegravir |
US20180280401A1 (en) * | 2015-10-14 | 2018-10-04 | The Global Alliance For Tb Drug Development, Inc. | Combination antibacterial composition and short-course antibacterial regimen |
-
2020
- 2020-06-26 GB GBGB2009684.8A patent/GB202009684D0/en not_active Ceased
-
2021
- 2021-06-23 TW TW110122867A patent/TW202216154A/zh unknown
- 2021-06-23 EP EP21737779.5A patent/EP4171572A1/en active Pending
- 2021-06-23 CA CA3180544A patent/CA3180544A1/en active Pending
- 2021-06-23 KR KR1020227044459A patent/KR20230028288A/ko active Search and Examination
- 2021-06-23 JP JP2022580247A patent/JP2023531086A/ja active Pending
- 2021-06-23 WO PCT/IB2021/055533 patent/WO2021260567A1/en unknown
- 2021-06-23 AR ARP210101730A patent/AR122718A1/es unknown
- 2021-06-23 AU AU2021296506A patent/AU2021296506A1/en active Pending
- 2021-06-23 IL IL298353A patent/IL298353A/en unknown
- 2021-06-23 MX MX2022015438A patent/MX2022015438A/es unknown
- 2021-06-23 US US18/001,635 patent/US20230285307A1/en active Pending
- 2021-06-23 BR BR112022026243A patent/BR112022026243A2/pt unknown
- 2021-06-23 CN CN202180043595.7A patent/CN115697344A/zh active Pending
-
2022
- 2022-12-23 CL CL2022003743A patent/CL2022003743A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
AR122718A1 (es) | 2022-09-28 |
JP2023531086A (ja) | 2023-07-20 |
BR112022026243A2 (pt) | 2023-01-17 |
KR20230028288A (ko) | 2023-02-28 |
CA3180544A1 (en) | 2021-12-30 |
EP4171572A1 (en) | 2023-05-03 |
MX2022015438A (es) | 2023-03-22 |
IL298353A (en) | 2023-01-01 |
CN115697344A (zh) | 2023-02-03 |
TW202216154A (zh) | 2022-05-01 |
AU2021296506A1 (en) | 2023-01-05 |
US20230285307A1 (en) | 2023-09-14 |
GB202009684D0 (en) | 2020-08-12 |
WO2021260567A1 (en) | 2021-12-30 |
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