CL2021000485A1 - Una cepa mutante de salmonella enteritidis; procedimiento para generar la cepa mutante; vacuna recombinante aviar de salmonella enteritidis, divisional de la solicitud 201903108 - Google Patents

Una cepa mutante de salmonella enteritidis; procedimiento para generar la cepa mutante; vacuna recombinante aviar de salmonella enteritidis, divisional de la solicitud 201903108

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Publication number
CL2021000485A1
CL2021000485A1 CL2021000485A CL2021000485A CL2021000485A1 CL 2021000485 A1 CL2021000485 A1 CL 2021000485A1 CL 2021000485 A CL2021000485 A CL 2021000485A CL 2021000485 A CL2021000485 A CL 2021000485A CL 2021000485 A1 CL2021000485 A1 CL 2021000485A1
Authority
CL
Chile
Prior art keywords
salmonella enteritidis
mutant strain
gene
procedure
vaccine
Prior art date
Application number
CL2021000485A
Other languages
English (en)
Inventor
Latasa Osta Cristina
Original Assignee
Farm Veterinarios Sac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farm Veterinarios Sac filed Critical Farm Veterinarios Sac
Publication of CL2021000485A1 publication Critical patent/CL2021000485A1/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente invención se refiere a una cepa mutante de Salmonella enteritidis 3934 con número de depósito CECT 7236 de la Colección Española de Cultivos Tipo que comprende la deleción de 12 genes que codifican enzimas diguanilato ciclasas, el gen rpoS y el gen waaL y la inserción de la secuencia completa del gen fibra AVA-I, además un procedimiento para generar la cepa mutante de Salmonella enteritidis 3934 con número de depósito CECT 7236 de la Colección Española de Cultivos Tipo que comprende la deleción de 12 genes que codifican enzimas diguanilato ciclasas, el gen rpoS y el gen waaL y la inserción de la secuencia completa del gen fibra AVA-I y una vacuna recombinante aviar de Salmonella enteritidis que comprende 3934 con número de depósito CECT 7236 de la Colección Española de Cultivos Tipo que comprende la deleción de 12 genes que codifican enzimas diguanilato ciclasas, el gen rpoS y el gen waaL y la inserción de la secuencia completa del gen fibra AVA-I.
CL2021000485A 2017-06-12 2021-02-26 Una cepa mutante de salmonella enteritidis; procedimiento para generar la cepa mutante; vacuna recombinante aviar de salmonella enteritidis, divisional de la solicitud 201903108 CL2021000485A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PE2017000992A PE20171768A1 (es) 2017-06-12 2017-06-12 Obtencion de una salmonela enteritidis tipo rugosa y sus modificaciones geneticas para uso como vacuna aviar

Publications (1)

Publication Number Publication Date
CL2021000485A1 true CL2021000485A1 (es) 2021-07-02

Family

ID=68069984

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2021000485A CL2021000485A1 (es) 2017-06-12 2021-02-26 Una cepa mutante de salmonella enteritidis; procedimiento para generar la cepa mutante; vacuna recombinante aviar de salmonella enteritidis, divisional de la solicitud 201903108

Country Status (10)

Country Link
US (1) US11242521B2 (es)
EP (1) EP3640323A4 (es)
CN (1) CN111094546A (es)
AR (1) AR112083A1 (es)
BR (1) BR112019018882A2 (es)
CL (1) CL2021000485A1 (es)
CO (1) CO2019012289A2 (es)
MX (1) MX2019010015A (es)
PE (1) PE20171768A1 (es)
WO (1) WO2018231078A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20211141A1 (es) * 2019-12-19 2021-06-25 Farm Veterinarios S A C Salmonella enteritidis recombinante y su uso como vacuna porcina
PE20201405A1 (es) * 2020-09-09 2020-12-02 Farm Veterinarios S A C Vacuna viva recombinante para sars-cov-2 basada en salmonella enteritidis recombinante
CN112941088B (zh) * 2021-02-04 2023-06-16 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 与布氏杆菌毒力相关的基因及其在布氏杆菌毒力评价及制备弱毒布氏杆菌中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2323839B2 (es) * 2007-07-24 2010-07-08 Universidad Complutense De Madrid Cepa viva atenuada de salmonella enterica serovar choleraesuis como vacuna y vehiculo vacunal para el ganado porcino.
ES2324084B1 (es) * 2007-11-21 2010-05-31 Universidad Publica De Navarra Procedimiento que permite producir modificaciones multiples en el cromosoma de bacterias gram negativas y cepas de salmonella deficientes en sintesis de c-di-gmp obtenidas por el mismo.
ES2646320T3 (es) * 2009-03-27 2017-12-13 Eidgenössische Technische Hochschule Zürich Salmonella enterica que presenta un N-glicano de C. Jejuni o derivados del mismo

Also Published As

Publication number Publication date
US11242521B2 (en) 2022-02-08
EP3640323A2 (en) 2020-04-22
WO2018231078A3 (es) 2019-03-07
AR112083A1 (es) 2019-09-18
CO2019012289A2 (es) 2020-01-17
MX2019010015A (es) 2019-11-21
BR112019018882A2 (pt) 2020-04-14
PE20171768A1 (es) 2017-12-21
EP3640323A4 (en) 2021-03-17
WO2018231078A2 (es) 2018-12-20
US20200370034A1 (en) 2020-11-26
CN111094546A (zh) 2020-05-01

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