CL2021000160A1 - Forma de dosificación farmacéutica administrable por vía oral con liberación modificada - Google Patents
Forma de dosificación farmacéutica administrable por vía oral con liberación modificadaInfo
- Publication number
- CL2021000160A1 CL2021000160A1 CL2021000160A CL2021000160A CL2021000160A1 CL 2021000160 A1 CL2021000160 A1 CL 2021000160A1 CL 2021000160 A CL2021000160 A CL 2021000160A CL 2021000160 A CL2021000160 A CL 2021000160A CL 2021000160 A1 CL2021000160 A1 CL 2021000160A1
- Authority
- CL
- Chile
- Prior art keywords
- diseases
- orally administered
- modified release
- pharmaceutical dosage
- dosage form
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 230000003176 fibrotic effect Effects 0.000 abstract 1
- 210000002216 heart Anatomy 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18185127 | 2018-07-24 | ||
| US16/043,567 US10905667B2 (en) | 2018-07-24 | 2018-07-24 | Orally administrable modified-release pharmaceutical dosage form |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2021000160A1 true CL2021000160A1 (es) | 2021-06-04 |
Family
ID=67314781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2021000160A CL2021000160A1 (es) | 2018-07-24 | 2021-01-20 | Forma de dosificación farmacéutica administrable por vía oral con liberación modificada |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP3826627B1 (https=) |
| JP (1) | JP2021532113A (https=) |
| KR (1) | KR20210035235A (https=) |
| CN (1) | CN112469402B (https=) |
| AU (1) | AU2019311234A1 (https=) |
| BR (1) | BR112020026644A2 (https=) |
| CA (1) | CA3107169A1 (https=) |
| CL (1) | CL2021000160A1 (https=) |
| CO (1) | CO2021000450A2 (https=) |
| CR (1) | CR20210043A (https=) |
| DO (1) | DOP2021000015A (https=) |
| EC (1) | ECSP21003707A (https=) |
| IL (1) | IL280083A (https=) |
| JO (1) | JOP20210019A1 (https=) |
| MA (1) | MA53368A (https=) |
| MX (1) | MX2021000904A (https=) |
| PE (1) | PE20210415A1 (https=) |
| PH (1) | PH12021550170A1 (https=) |
| SG (1) | SG11202100369WA (https=) |
| TW (1) | TW202019402A (https=) |
| UY (1) | UY38308A (https=) |
| WO (1) | WO2020020789A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020245342A1 (en) | 2019-06-07 | 2020-12-10 | Bayer Aktiengesellschaft | The use of sgc activators for the treatment of ophthalmologic diseases |
| CN112557533A (zh) * | 2020-11-29 | 2021-03-26 | 北京康立生医药技术开发有限公司 | 一种恩格列净的分析方法 |
| US20240317696A1 (en) * | 2021-05-14 | 2024-09-26 | Medshine Discovery Inc. | Alkyl carboxylic acid compounds and application thereof |
| EP4536205A1 (en) | 2022-06-09 | 2025-04-16 | Bayer Aktiengesellschaft | Soluble guanylate cyclase activators for use in the treatment of heart failure with preserved ejection fraction in women |
| CN117982443B (zh) * | 2022-10-31 | 2026-03-06 | 优辉药业(北京)有限公司 | 一种达格列净二甲双胍缓释片剂 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| GB1478759A (en) | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
| US4063064A (en) | 1976-02-23 | 1977-12-13 | Coherent Radiation | Apparatus for tracking moving workpiece by a laser beam |
| US4111202A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for the controlled and delivery of agent over time |
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| NZ206600A (en) | 1983-05-11 | 1987-01-23 | Alza Corp | Osmotic drug delivery device |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| ES2039287T3 (es) | 1987-01-14 | 1993-09-16 | Ciba-Geigy Ag | Procedimiento para la obtencion de un sistema terapeutico peroral para productos activos dificilmente solubles. |
| DE19747261A1 (de) | 1997-10-25 | 1999-04-29 | Bayer Ag | Osmotisches Arzneimittelfreisetzungssystem |
| DE19834044A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Neue substituierte Pyrazolderivate |
| DE19834047A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Substituierte Pyrazolderivate |
| ATE433318T1 (de) * | 1999-02-10 | 2009-06-15 | Pfizer Prod Inc | Osmotisches system zur verabreichung von wirkstoffen, die feste amorphe dispersionen enthalten |
| AR031176A1 (es) | 2000-11-22 | 2003-09-10 | Bayer Ag | Nuevos derivados de pirazolpiridina sustituidos con piridina |
| US20030161882A1 (en) | 2002-02-01 | 2003-08-28 | Waterman Kenneth C. | Osmotic delivery system |
| DE10220570A1 (de) | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamat-substituierte Pyrazolopyridine |
| DE102004062475A1 (de) | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| DE102008059206A1 (de) | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
| DE102010021637A1 (de) | 2010-05-26 | 2011-12-01 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung |
| PE20130779A1 (es) | 2010-07-09 | 2013-06-21 | Bayer Ip Gmbh | Pirimidinas y triazinas condensadas y su uso |
| DE102010040233A1 (de) | 2010-09-03 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Bicyclische Aza-Heterocyclen und ihre Verwendung |
| DE102010043379A1 (de) | 2010-11-04 | 2012-05-10 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 6-Fluor-1H-Pyrazolo[4,3-b]pyridine und ihre Verwendung |
| DE102011007272A1 (de) * | 2011-04-13 | 2012-10-18 | Bayer Pharma Aktiengesellschaft | Verzweigte 3-Phenylpropionsäure-Derivate und ihre Verwendung |
| UY34856A (es) * | 2012-07-03 | 2013-12-31 | Bayer Pharma AG | Formas de presentación farmacéuticas que contienen 5-cloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4- morfolinil)-fenil]-1,3-oxazolidin-5-il}-metil)-2-tiofencarboxamida |
| WO2019105881A1 (de) | 2017-12-01 | 2019-06-06 | Bayer Pharma Aktiengesellschaft | Verfahren zur herstellung von (3s)-3-(4-chlor-3-{[(2s,3r)-2-(4-chlorphenyl)-4,4,4-trifluor-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropansäure und dessen kristalline form für die verwendung als pharmazeutischer wirkstoff |
-
2019
- 2019-07-19 CA CA3107169A patent/CA3107169A1/en active Pending
- 2019-07-19 JP JP2021503578A patent/JP2021532113A/ja active Pending
- 2019-07-19 EP EP19740580.6A patent/EP3826627B1/de active Active
- 2019-07-19 JO JOP/2021/0019A patent/JOP20210019A1/ar unknown
- 2019-07-19 AU AU2019311234A patent/AU2019311234A1/en not_active Abandoned
- 2019-07-19 BR BR112020026644-2A patent/BR112020026644A2/pt not_active Application Discontinuation
- 2019-07-19 UY UY0001038308A patent/UY38308A/es not_active Application Discontinuation
- 2019-07-19 CR CR20210043A patent/CR20210043A/es unknown
- 2019-07-19 MX MX2021000904A patent/MX2021000904A/es unknown
- 2019-07-19 WO PCT/EP2019/069561 patent/WO2020020789A1/de not_active Ceased
- 2019-07-19 MA MA053368A patent/MA53368A/fr unknown
- 2019-07-19 CN CN201980049223.8A patent/CN112469402B/zh active Active
- 2019-07-19 PE PE2021000084A patent/PE20210415A1/es unknown
- 2019-07-19 KR KR1020217004994A patent/KR20210035235A/ko not_active Withdrawn
- 2019-07-19 TW TW108125542A patent/TW202019402A/zh unknown
- 2019-07-19 SG SG11202100369WA patent/SG11202100369WA/en unknown
-
2021
- 2021-01-11 IL IL280083A patent/IL280083A/en unknown
- 2021-01-18 EC ECSENADI20213707A patent/ECSP21003707A/es unknown
- 2021-01-19 CO CONC2021/0000450A patent/CO2021000450A2/es unknown
- 2021-01-20 DO DO2021000015A patent/DOP2021000015A/es unknown
- 2021-01-20 CL CL2021000160A patent/CL2021000160A1/es unknown
- 2021-01-22 PH PH12021550170A patent/PH12021550170A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JOP20210019A1 (ar) | 2021-01-24 |
| CN112469402A (zh) | 2021-03-09 |
| UY38308A (es) | 2020-02-28 |
| TW202019402A (zh) | 2020-06-01 |
| ECSP21003707A (es) | 2021-02-26 |
| MX2021000904A (es) | 2021-03-31 |
| KR20210035235A (ko) | 2021-03-31 |
| BR112020026644A2 (pt) | 2021-03-23 |
| CR20210043A (es) | 2021-03-09 |
| CN112469402B (zh) | 2024-05-14 |
| MA53368A (fr) | 2021-06-02 |
| CO2021000450A2 (es) | 2021-01-29 |
| PH12021550170A1 (en) | 2021-09-13 |
| EP3826627C0 (de) | 2023-10-18 |
| IL280083A (en) | 2021-03-01 |
| SG11202100369WA (en) | 2021-02-25 |
| AU2019311234A1 (en) | 2021-02-04 |
| WO2020020789A1 (de) | 2020-01-30 |
| EP3826627A1 (de) | 2021-06-02 |
| PE20210415A1 (es) | 2021-03-04 |
| DOP2021000015A (es) | 2021-02-15 |
| EP3826627B1 (de) | 2023-10-18 |
| CA3107169A1 (en) | 2020-01-30 |
| JP2021532113A (ja) | 2021-11-25 |
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