CL2019003271A1 - Selección y uso de fracciones de células de cordón umbilical adecuadas para trasplante. - Google Patents
Selección y uso de fracciones de células de cordón umbilical adecuadas para trasplante.Info
- Publication number
- CL2019003271A1 CL2019003271A1 CL2019003271A CL2019003271A CL2019003271A1 CL 2019003271 A1 CL2019003271 A1 CL 2019003271A1 CL 2019003271 A CL2019003271 A CL 2019003271A CL 2019003271 A CL2019003271 A CL 2019003271A CL 2019003271 A1 CL2019003271 A1 CL 2019003271A1
- Authority
- CL
- Chile
- Prior art keywords
- transplantation
- selection
- negative
- umbilical cord
- blood
- Prior art date
Links
- 238000002054 transplantation Methods 0.000 title abstract 5
- 210000003954 umbilical cord Anatomy 0.000 title abstract 2
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 abstract 4
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 abstract 4
- 210000004369 blood Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004700 fetal blood Anatomy 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Abstract
PROCEDIMIENTOS DE SELECCIÓN DE UNIDADES SANGUÍNEAS DE CORDÓN UMBILICAL PARA EXPANSIÓN EX VIVO, SEPARACIÓN DE FRACCIONES CD133+/CD34+ POSITIVAS Y CD133+/CD34+ NEGATIVAS NO CULTIVADAS, PROCEDIMIENTOS DE EXPANSIÓN DE LA FRACCIÓN CD133+/CD34+ SELECCIONADA, DE SELECCIÓN DE POBLACIONES EXPANDIDAS DE CÉLULAS SANGUÍNEAS DE CORDÓN CD133+/CD34+ PARA TRASPLANTE A SUJETOS QUE LO NECESITAN Y USO TERAPÉUTICO DE FRACCIONES SANGUÍNEAS DE CORDÓN CD133+/CD34+ EXPANDIDAS EX VIVO SELECCIONADAS Y CD133/CD34 NEGATIVAS NO SELECCIONADAS ADECUADAS PARA EL TRASPLANTE EN EL ENTORNO CLÍNICO, PARA EL TRATAMIENTO DE NEOPLASIAS HEMATOLÓGICAS MALIGNAS. LA PRESENTE INVENCIÓN TAMBIÉN PREVÉ KITS QUE COMPRENDEN FRACCIONES SANGUÍNEAS DE CORDÓN EXPANDIDAS Y NO SELECCIONADAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762506699P | 2017-05-16 | 2017-05-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2019003271A1 true CL2019003271A1 (es) | 2020-05-29 |
Family
ID=64274416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2019003271A CL2019003271A1 (es) | 2017-05-16 | 2019-11-14 | Selección y uso de fracciones de células de cordón umbilical adecuadas para trasplante. |
Country Status (10)
Country | Link |
---|---|
US (2) | US11730771B2 (es) |
EP (1) | EP3634436A4 (es) |
JP (1) | JP7295810B2 (es) |
CN (2) | CN110996978B (es) |
AU (1) | AU2018270407A1 (es) |
BR (1) | BR112019024113A2 (es) |
CA (1) | CA3063674A1 (es) |
CL (1) | CL2019003271A1 (es) |
MX (1) | MX2019013613A (es) |
WO (1) | WO2018211509A2 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3063674A1 (en) | 2017-05-16 | 2018-11-22 | Gamida-Cell Ltd. | Selection and use of umbilical cord cell fractions suitable for transplantation |
CA3064055A1 (en) | 2017-05-16 | 2018-11-22 | Gamida-Cell Ltd. | Selection and use of umbilical cord cell fractions suitable for transplantation |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL152904A0 (en) | 2002-01-24 | 2003-06-24 | Gamida Cell Ltd | Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations |
WO2004096972A2 (en) | 2003-05-02 | 2004-11-11 | Insception Bioscience, Inc. | Apparatus and methods for amplification of blood stem cell numbers |
WO2006006171A2 (en) | 2004-07-14 | 2006-01-19 | Gamida-Cell Ltd. | Expansion of stem/progenitor cells by inhibition of enzymatic reactions catalyzed by the sir2 family of enzymes |
EP2390312A1 (en) | 2005-11-29 | 2011-11-30 | Gamida Cell Ltd. | Methods of improving stem cell homing and engraftment |
US8846393B2 (en) | 2005-11-29 | 2014-09-30 | Gamida-Cell Ltd. | Methods of improving stem cell homing and engraftment |
RU2360965C1 (ru) | 2007-11-01 | 2009-07-10 | Общество с ограниченной ответственностью "Лаборатория клеточного мониторинга" | СПОСОБ УВЕЛИЧЕНИЯ КОЛИЧЕСТВА ГЕМОПОЭТИЧЕСКИХ НЕДИФФЕРЕНЦИРОВАННЫХ СТВОЛОВЫХ КЛЕТОК ПАЦИЕНТА ex vivo |
BRPI1007651A2 (pt) | 2009-05-07 | 2019-09-24 | Gamida Cell Ltd | método de seleção de uma população de células tronco hematopoiéticas expandidas ex-vivo adequadas para transplante, população de células tronco hematopoiéticas expandidas selecionadas adequadas para transplante, método de tratamento de uma doença hematológica ou condição em um indivíduo carente dele e artigo de fabricação |
US20120093782A1 (en) | 2009-05-13 | 2012-04-19 | Grove Robert I | Enhanced Hematopoietic Stem Cell Engraftment |
PT106225B (pt) | 2012-03-23 | 2017-11-03 | Inst Superior Técnico | Processo de expansão ex vivo de células estaminais em biorreactor |
CN104357396A (zh) * | 2014-11-03 | 2015-02-18 | 赛欧帕克(江苏)干细胞生物工程有限公司 | 一种提取早期造血前体干细胞的方法及其应用 |
DK3313879T3 (da) | 2015-06-24 | 2022-03-14 | Hoffmann La Roche | Anti-transferrinreceptor-antistoffer med tilpasset affinitet |
BR112018011327A2 (pt) | 2015-12-04 | 2018-12-04 | Hutchinson Fred Cancer Res | usos de populações expandidas de células-tronco/progenitoras hematopoiéticas |
CA3063674A1 (en) | 2017-05-16 | 2018-11-22 | Gamida-Cell Ltd. | Selection and use of umbilical cord cell fractions suitable for transplantation |
CA3064055A1 (en) | 2017-05-16 | 2018-11-22 | Gamida-Cell Ltd. | Selection and use of umbilical cord cell fractions suitable for transplantation |
CL2019003272A1 (es) | 2019-11-14 | 2020-05-29 | Gamida Cell Ltd | Selección y uso de fracciones de células del cordón umbilical adecuadas para trasplante. |
-
2018
- 2018-05-16 CA CA3063674A patent/CA3063674A1/en active Pending
- 2018-05-16 AU AU2018270407A patent/AU2018270407A1/en active Pending
- 2018-05-16 MX MX2019013613A patent/MX2019013613A/es unknown
- 2018-05-16 JP JP2019563380A patent/JP7295810B2/ja active Active
- 2018-05-16 CN CN201880047411.2A patent/CN110996978B/zh active Active
- 2018-05-16 US US16/614,002 patent/US11730771B2/en active Active
- 2018-05-16 EP EP18802611.6A patent/EP3634436A4/en active Pending
- 2018-05-16 WO PCT/IL2018/050537 patent/WO2018211509A2/en unknown
- 2018-05-16 BR BR112019024113-2A patent/BR112019024113A2/pt unknown
- 2018-05-16 CN CN202410217544.7A patent/CN117904049A/zh active Pending
-
2019
- 2019-11-14 CL CL2019003271A patent/CL2019003271A1/es unknown
-
2023
- 2023-06-28 US US18/342,896 patent/US20230338433A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3634436A2 (en) | 2020-04-15 |
CN117904049A (zh) | 2024-04-19 |
CN110996978A (zh) | 2020-04-10 |
CA3063674A1 (en) | 2018-11-22 |
US20230338433A1 (en) | 2023-10-26 |
JP2020520237A (ja) | 2020-07-09 |
WO2018211509A3 (en) | 2018-12-27 |
US11730771B2 (en) | 2023-08-22 |
MX2019013613A (es) | 2020-07-20 |
US20200138871A1 (en) | 2020-05-07 |
CN110996978B (zh) | 2024-03-19 |
EP3634436A4 (en) | 2021-03-24 |
JP7295810B2 (ja) | 2023-06-21 |
WO2018211509A2 (en) | 2018-11-22 |
BR112019024113A2 (pt) | 2020-06-02 |
AU2018270407A1 (en) | 2020-01-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2019000259A1 (es) | Anticuerpos, antimiostatina, polipéptidos que contienen regiones fc variantes y métodos de uso.(divisional solicitud 201701584) | |
CL2018002763A1 (es) | Moléculas de unión a bcma y métodos de uso de las mismas. | |
CL2017000651A1 (es) | Anticuerpos anti-glucagón y sus usos | |
CO2019000395A2 (es) | Genes de mini–distrofina optimizados y casetes de expresión y su uso | |
CO2020005981A2 (es) | Anticuerpos anti-tau y uso de los mismos | |
CR20170240A (es) | Anticuerpos anti-interleucina-33 y sus usos | |
TR201903526T4 (tr) | Sistein-mühendislik uygulanmış antikorlar içeren konjuge edilmiş bileşikler. | |
CR20120086A (es) | Anticuerpos humanos de alta afinidad para la angiopoyetina-2 humana | |
CL2019003271A1 (es) | Selección y uso de fracciones de células de cordón umbilical adecuadas para trasplante. | |
CR20160270A (es) | ANTICUERPOS ANTI-TAU (pS422) HUMANIZADOS Y MÉTODOS DE UTILIZACIÓN | |
CO7280144A2 (es) | Moléculas de anticuerpo anti-gcc y uso de las mismas para probar la susceptibilidad a la terapia dirigida a gcc | |
CL2017002101A1 (es) | Dispositivo, plataforma y ensayo para evaluación de células | |
CO2019002607A2 (es) | Biomarcadores de metabolitos para enfermedades asociadas con el sistema de activación por contacto | |
DOP2016000220A (es) | PROTEÍNAS DE FUSIÓN TATk-CDKL5, COMPOSICIONES, FORMULACIONES Y USO DE ESTAS. | |
AR117220A1 (es) | Métodos de expansión ex vivo de células asesinas naturales y sus usos | |
CO2018005846A2 (es) | Ensayos y metodos para seleccionar un regimen de tratamiento para un sujeto con leucemia | |
MX2017009485A (es) | Detección y aislamiento de células fetales basadas en microfluidos para prueba prenatal no invasiva. | |
CO2019008675A2 (es) | Anticuerpos anti-lag3 radiomarcados para la obtención de imágenes mediante inmuno-pet | |
CO2019002751A2 (es) | Composiciones marcadoras, y metodos para fabricar y usar las mismas | |
CL2019003272A1 (es) | Selección y uso de fracciones de células del cordón umbilical adecuadas para trasplante. | |
MX2019013614A (es) | Seleccion y uso de fracciones de celulas del cordon umbilical adecuadas para trasplante. | |
CL2017002680A1 (es) | Construcciones de calicheamicina y sus métodos de uso | |
AR112602A1 (es) | ANTICUERPOS ANTI-TrkB | |
TWD192672S (zh) | 匣倉 | |
CO2019002599A2 (es) | Biomarcadores proteicos para enfermedades asociadas con el sistema de activación por contacto |