CL2019002220A1 - Gasotransmisor electroquímico que genera composiciones y métodos de uso de los mismos y apósitos y sistemas de tratamiento que incorpora los mismos. - Google Patents
Gasotransmisor electroquímico que genera composiciones y métodos de uso de los mismos y apósitos y sistemas de tratamiento que incorpora los mismos.Info
- Publication number
- CL2019002220A1 CL2019002220A1 CL2019002220A CL2019002220A CL2019002220A1 CL 2019002220 A1 CL2019002220 A1 CL 2019002220A1 CL 2019002220 A CL2019002220 A CL 2019002220A CL 2019002220 A CL2019002220 A CL 2019002220A CL 2019002220 A1 CL2019002220 A1 CL 2019002220A1
- Authority
- CL
- Chile
- Prior art keywords
- gasotransmitter
- methods
- compositions
- electrochemical
- dressings
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000027756 respiratory electron transport chain Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01008—Non-adhesive bandages or dressings characterised by the material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/114—Nitric oxide, i.e. NO
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B17/00—Sulfur; Compounds thereof
- C01B17/48—Sulfur dioxide; Sulfurous acid
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
- C01B21/50—Nitrous acid; Salts thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
La invención se refiere a composiciones que comprenden un mediador orgánico electroquímico y una sal gasotransmisora que se convierte en un gasotransmisor por transferencia de electrones. También se divulgan vendas y vendajes que comprenden el gasotransmisor y métodos de elaboración de gasotransmisores, que comprende exponer las composiciones a un voltaje suficiente para reducir el mediador orgánico soluble en agua. Ader'nás se divulgan métodos de tratamiento para una variedad de estados de trauma y enfermedades mediante la aplicación de una cantidad terapéuticamente efectiva de al menos un gasotransmisor a los mismos, y métodos de generar una dosis efectiva de la gasotransmisor generados de reacción electrolítica que afecta (as composiciones de la generación del gasotransmisor.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762457039P | 2017-02-09 | 2017-02-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2019002220A1 true CL2019002220A1 (es) | 2020-01-03 |
Family
ID=63038868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2019002220A CL2019002220A1 (es) | 2017-02-09 | 2019-08-07 | Gasotransmisor electroquímico que genera composiciones y métodos de uso de los mismos y apósitos y sistemas de tratamiento que incorpora los mismos. |
Country Status (14)
Country | Link |
---|---|
US (1) | US10342706B2 (es) |
EP (1) | EP3579888B1 (es) |
JP (1) | JP6989157B2 (es) |
KR (1) | KR102189597B1 (es) |
CN (1) | CN110461374B (es) |
AU (1) | AU2018218200B2 (es) |
CA (1) | CA3053141A1 (es) |
CL (1) | CL2019002220A1 (es) |
ES (1) | ES2965705T3 (es) |
IL (1) | IL268577B (es) |
MX (1) | MX2019009384A (es) |
PL (1) | PL3579888T3 (es) |
WO (1) | WO2018147986A1 (es) |
ZA (1) | ZA201905431B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20190328774A1 (en) * | 2017-02-09 | 2019-10-31 | Noxsano Inc. | Electrochemical gasotransmitter generating compositions and methods of using same and dressings and treatment systems incorporating same |
US11369682B2 (en) | 2018-04-25 | 2022-06-28 | Noxsano Inc. | Light activated gasotransmitter generating compositions |
EP3804731A4 (en) * | 2018-06-08 | 2022-04-06 | Sumitomo Seika Chemicals Co., Ltd. | COMPOSITION FOR THE TREATMENT OF SKIN WOUNDS |
EP3804733A4 (en) | 2018-06-08 | 2022-03-16 | Sumitomo Seika Chemicals Co., Ltd. | COMPOSITION FOR INFLAMMATORY GASTROINTESTINAL DISEASES |
BR112021013471A2 (pt) * | 2019-01-11 | 2021-09-14 | Noxsano Inc. | Composições que geram gasotransmissor eletroquímico e células bimetálicas para a geração de gasotransmissores |
TWI694844B (zh) | 2019-01-29 | 2020-06-01 | 明基材料股份有限公司 | 硫化氫緩釋敷料及其製造方法 |
CN109793919B (zh) * | 2019-02-01 | 2022-01-14 | 明基材料(芜湖)有限公司 | 硫化氢缓释敷料及其制造方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5797887A (en) * | 1996-08-27 | 1998-08-25 | Novovasc Llc | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
US5994444A (en) * | 1997-10-16 | 1999-11-30 | Medtronic, Inc. | Polymeric material that releases nitric oxide |
US6103275A (en) * | 1998-06-10 | 2000-08-15 | Nitric Oxide Solutions | Systems and methods for topical treatment with nitric oxide |
US20090036516A1 (en) * | 2003-01-13 | 2009-02-05 | Ctg Pharma S.R.L. | Compounds for treating metabolic syndrome |
JP5303465B2 (ja) * | 2006-10-05 | 2013-10-02 | イカリア, インコーポレイテッド | 液体カルコゲナイド組成物ならびにそれを製造および使用する方法 |
CA2728789A1 (en) * | 2008-06-24 | 2009-12-30 | Micropharma Limited | Nitric oxide compositions and devices and methods for cosmesis |
EP2519297A4 (en) * | 2009-12-31 | 2013-08-21 | Univ Ohio | SYSTEMS AND METHODS FOR PROMOTING HEALING |
CN103813766B (zh) * | 2011-09-14 | 2016-01-20 | 3M创新有限公司 | 具有阀门的正压医用敷料和包含所述敷料的套件 |
ES2739628T3 (es) | 2011-09-14 | 2020-02-03 | Nuevas Alternativas Naturales S A De C V | Preparación y composiciones de azufre a cerovalencia con alta biodisponibilidad y usos de las mismas |
US9480785B2 (en) * | 2012-03-30 | 2016-11-01 | The Regents Of The University Of Michigan | Nitric oxide delivery devices |
CN104394923B (zh) * | 2012-03-30 | 2017-07-14 | 密执安大学评议会 | 一氧化氮递送装置 |
BR102013022095A2 (pt) | 2013-08-29 | 2016-08-02 | Mineração Tabiporã Ltda | processo para a obtenção de sulfeto de hidrogênio a partir da redução de sulfato de cálcio e da decomposição do sulfeto de cálcio com cloreto de magnésio |
MX351120B (es) * | 2013-11-07 | 2017-10-03 | Bsn Medical Gmbh | Apósito médico. |
-
2018
- 2018-01-18 PL PL18751918.6T patent/PL3579888T3/pl unknown
- 2018-01-18 CN CN201880022253.5A patent/CN110461374B/zh active Active
- 2018-01-18 ES ES18751918T patent/ES2965705T3/es active Active
- 2018-01-18 KR KR1020197026047A patent/KR102189597B1/ko active IP Right Grant
- 2018-01-18 US US15/874,665 patent/US10342706B2/en active Active
- 2018-01-18 WO PCT/US2018/014265 patent/WO2018147986A1/en unknown
- 2018-01-18 MX MX2019009384A patent/MX2019009384A/es unknown
- 2018-01-18 EP EP18751918.6A patent/EP3579888B1/en active Active
- 2018-01-18 AU AU2018218200A patent/AU2018218200B2/en active Active
- 2018-01-18 CA CA3053141A patent/CA3053141A1/en active Pending
- 2018-01-18 JP JP2019565149A patent/JP6989157B2/ja active Active
-
2019
- 2019-08-07 CL CL2019002220A patent/CL2019002220A1/es unknown
- 2019-08-07 IL IL268577A patent/IL268577B/en active IP Right Grant
- 2019-08-16 ZA ZA2019/05431A patent/ZA201905431B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES2965705T3 (es) | 2024-04-16 |
MX2019009384A (es) | 2019-12-11 |
WO2018147986A1 (en) | 2018-08-16 |
ZA201905431B (en) | 2020-05-27 |
AU2018218200A1 (en) | 2019-08-29 |
KR20190108169A (ko) | 2019-09-23 |
US10342706B2 (en) | 2019-07-09 |
KR102189597B1 (ko) | 2020-12-14 |
EP3579888C0 (en) | 2023-09-27 |
PL3579888T3 (pl) | 2024-05-27 |
CN110461374A (zh) | 2019-11-15 |
BR112019016486A2 (pt) | 2020-04-07 |
US20180221210A1 (en) | 2018-08-09 |
JP6989157B2 (ja) | 2022-01-05 |
CN110461374B (zh) | 2022-05-31 |
EP3579888B1 (en) | 2023-09-27 |
EP3579888A4 (en) | 2021-04-07 |
AU2018218200B2 (en) | 2023-11-23 |
EP3579888A1 (en) | 2019-12-18 |
CA3053141A1 (en) | 2018-08-16 |
JP2020511526A (ja) | 2020-04-16 |
IL268577A (en) | 2019-09-26 |
IL268577B (en) | 2020-03-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2019002220A1 (es) | Gasotransmisor electroquímico que genera composiciones y métodos de uso de los mismos y apósitos y sistemas de tratamiento que incorpora los mismos. | |
CL2021001292A1 (es) | Terapia de combinación que incluye un inhibidor de krasg12c y uno o más agentes farmacéuticamente activos adicionales para el tratamiento de cánceres | |
CO2020009225A2 (es) | Análogos de dihidrobenzofurano e indeno como inhibidores del sarcómero cardíaco | |
UY38160A (es) | Partículas implantables y métodos relacionados | |
CL2020002695A1 (es) | Péptidos macrocíclicos contra actinetobacter baumannii | |
CL2019002204A1 (es) | Compuestos inhibidores del vih. | |
CO2020006523A2 (es) | Compuestos moduladores de sting y métodos de elaboración y uso | |
CO2022018811A2 (es) | Inhibidores de la proteína kras g12c y usos de estos | |
UY37461A (es) | 1,2,4 – triazolonas 2,4,5 trisustituida | |
UY37997A (es) | Agentes antivirales contra la hepatitis b | |
CO2020010552A2 (es) | Compuestos | |
PH12020552148A1 (en) | Purinone compounds and their use in treating cancer | |
BR112012023421A2 (pt) | composição farmacêutica para tratamento de aumento de pressão intraocular | |
EA201791094A1 (ru) | Аналоги простых эфиров фосфолипидов в качестве носителей лекарственных средств, нацеленных на раковые клетки | |
MX2019013561A (es) | Compuestos de pirrolopiridina-anilina para el tratamiento de trastornos dermicos. | |
CO2020014677A2 (es) | Compuestos tetrahidro-1h-pirazino[2,1-a]isoindolilquinolina para el tratamiento de enfermedades autoinmunes | |
EA202192433A1 (ru) | Соединения, полезные в терапии вич | |
CO2022000481A2 (es) | Inhibidores de enzimas | |
CL2024000560A1 (es) | Inhibidores de indolina de kif18a | |
CO2020013834A2 (es) | Ciertos compuestos de pladienolida y métodos de uso | |
CO2021013166A2 (es) | Compuestos de hexahidro-1h-pirazino[1,2-a]pirazina para el tratamiento de una enfermedad autoinmunitaria | |
PE20211113A1 (es) | Agentes de liberacion de gas antimicrobianos y sistemas y metodos para utilizarlos | |
CL2021002946A1 (es) | Un derivado de tetrahidroisoquinolina sustituido como modulador alostérico positivo de d1 | |
DOP2019000100A (es) | Derivados de naftiridinona y su uso en el tratamiento de la arritmia | |
CL2020003367A1 (es) | Composición que comprende el oligonucleótido antisentido y su uso para el tratamiento de la distrofia muscular de duchenne |