CL2019000920A1 - Métodos de preservar la actividad biológica de los ácidos ribonucleicos. - Google Patents

Métodos de preservar la actividad biológica de los ácidos ribonucleicos.

Info

Publication number
CL2019000920A1
CL2019000920A1 CL2019000920A CL2019000920A CL2019000920A1 CL 2019000920 A1 CL2019000920 A1 CL 2019000920A1 CL 2019000920 A CL2019000920 A CL 2019000920A CL 2019000920 A CL2019000920 A CL 2019000920A CL 2019000920 A1 CL2019000920 A1 CL 2019000920A1
Authority
CL
Chile
Prior art keywords
preserving
biological activity
methods
ribonucleic acids
acids
Prior art date
Application number
CL2019000920A
Other languages
English (en)
Inventor
Pascale Feldmann
Jeffrey David Fowler
Isabelle Maillet
Nema Devi Jhurry
Pujol Marta Omedes
Original Assignee
Syngenta Participations Ag
Devgen Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag, Devgen Nv filed Critical Syngenta Participations Ag
Publication of CL2019000920A1 publication Critical patent/CL2019000920A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/10—Animals; Substances produced thereby or obtained therefrom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60—Isolated nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity
    • C12N2320/51—Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCIÓN PROPORCIONA UN MÉTODO DE CONSERVAR SUSTANCIALMENTE O PRESERVAR DE OTRA FORMA LA ACTIVIDAD BIOLÓGICA DE UN ARNBC, PRESENTE EN UNA CÉLULA, PARA SILENCIAR DE FORMA POSTRANSCRIPCIONAL LA EXPRESIÓN DE UN GEN EN UN ORGANISMO DIANA, QUE COMPRENDE LA ETAPA DE AÑADIR A LA COMPOSICIÓN CELULAR UN COMPUESTO QUE TIENE LA FUNCIÓN DE UN ÁCIDO Y/O AGENTE RETICULANTE PROTEICO O DE TIPO AMINA. LA INVENCIÓN TAMBIÉN COMPRENDE COMPOSICIONES QUE COMPRENDEN LAS CÉLULAS QUE COMPRENDEN ARNBC, Y ÁCIDOS Y/O AGENTES RETICULANTES PROTEICOS, ASÍ COMO EL USO DE DICHOS ÁCIDOS Y/O AGENTES RETICULANTES EN EL MÉTODO.
CL2019000920A 2016-10-05 2019-04-04 Métodos de preservar la actividad biológica de los ácidos ribonucleicos. CL2019000920A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662404249P 2016-10-05 2016-10-05

Publications (1)

Publication Number Publication Date
CL2019000920A1 true CL2019000920A1 (es) 2019-06-21

Family

ID=60051497

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2019000920A CL2019000920A1 (es) 2016-10-05 2019-04-04 Métodos de preservar la actividad biológica de los ácidos ribonucleicos.

Country Status (12)

Country Link
US (1) US11286476B2 (es)
EP (1) EP3522719A1 (es)
JP (1) JP2019531078A (es)
KR (1) KR102482816B1 (es)
CN (1) CN109963468B (es)
AU (1) AU2017339022B2 (es)
CA (1) CA3036620A1 (es)
CL (1) CL2019000920A1 (es)
PH (1) PH12019500738A1 (es)
RU (1) RU2769831C2 (es)
WO (1) WO2018065303A1 (es)
ZA (1) ZA201901742B (es)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2327224A (en) * 1997-07-09 1999-01-20 Mayo Foundation Gene transfer to adipocytes
CN1280192A (zh) * 2000-06-21 2001-01-17 张国庆 一种细胞染色液
JP4429269B2 (ja) * 2003-02-10 2010-03-10 大正製薬株式会社 アポトーシス誘導遺伝子およびその利用
AR048685A1 (es) * 2004-04-09 2006-05-17 Monsanto Technology Llc Metodos para el control de infestaciones de insectos en plantas.
JPWO2006093083A1 (ja) * 2005-03-03 2008-08-07 和光純薬工業株式会社 架橋剤、架橋法、遺伝子発現調節法及び遺伝子機能調査法
CA2610644A1 (en) * 2005-05-31 2006-12-07 Devgen Nv Rnai for control of insects and arachnids
US7943819B2 (en) * 2005-09-16 2011-05-17 Monsanto Technology Llc Methods for genetic control of insect infestations in plants and compositions thereof
EP2374462A3 (en) * 2006-01-12 2011-12-14 deVGen N.V. Methods for controlling pests using RNAi
US20070269892A1 (en) * 2006-05-18 2007-11-22 Nastech Pharmaceutical Company Inc. FORMULATIONS FOR INTRACELLULAR DELIVERY dsRNA
JP5175036B2 (ja) * 2006-05-22 2013-04-03 独立行政法人国立病院機構 ヒト軟骨細胞形質維持因子
EP2175020A1 (en) * 2008-10-13 2010-04-14 Roche Diagnostics GmbH Reduction of RNase activity in complex fluidic samples
US20100257634A1 (en) * 2009-04-03 2010-10-07 Venganza Inc. Bioassay for gene silencing constructs
WO2014110205A1 (en) * 2013-01-11 2014-07-17 Children's Medical Center Corporation Methods and compositions for the production of sirnas
AU2014308991B2 (en) * 2013-08-21 2019-02-14 Janssen Biopharma, Inc. Antiviral compounds
CN103483872B (zh) * 2013-09-30 2015-08-19 青岛农业大学 用于肿瘤组织细胞的染色剂组合物及其制备方法
TW201520333A (zh) * 2013-11-29 2015-06-01 Tci Gene Inc 保存去氧核醣核酸之方法
EP3581654B1 (en) * 2013-12-27 2021-03-31 Dicerna Pharmaceuticals, Inc. Methods and compositions for the specific inhibition of glycolate oxidase (hao1) by double-stranded rna
CN108135182A (zh) * 2015-10-05 2018-06-08 先正达参股股份有限公司 保存核糖核酸生物活性的方法

Also Published As

Publication number Publication date
PH12019500738A1 (en) 2019-08-05
ZA201901742B (en) 2019-12-18
BR112019006728A2 (pt) 2019-06-25
CN109963468B (zh) 2022-10-04
RU2019112812A (ru) 2020-11-06
AU2017339022A1 (en) 2019-03-28
CN109963468A (zh) 2019-07-02
RU2019112812A3 (es) 2021-01-29
WO2018065303A1 (en) 2018-04-12
KR102482816B1 (ko) 2022-12-28
AU2017339022B2 (en) 2022-06-02
US20200045977A1 (en) 2020-02-13
US11286476B2 (en) 2022-03-29
KR20190062421A (ko) 2019-06-05
EP3522719A1 (en) 2019-08-14
RU2769831C2 (ru) 2022-04-06
CA3036620A1 (en) 2018-04-12
JP2019531078A (ja) 2019-10-31

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