CL2018000357A1 - Polipéptidos mrka, anticuerpos y usos los mismos - Google Patents
Polipéptidos mrka, anticuerpos y usos los mismosInfo
- Publication number
- CL2018000357A1 CL2018000357A1 CL2018000357A CL2018000357A CL2018000357A1 CL 2018000357 A1 CL2018000357 A1 CL 2018000357A1 CL 2018000357 A CL2018000357 A CL 2018000357A CL 2018000357 A CL2018000357 A CL 2018000357A CL 2018000357 A1 CL2018000357 A1 CL 2018000357A1
- Authority
- CL
- Chile
- Prior art keywords
- klebsiella
- antibodies
- mrka
- fragments
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0266—Klebsiella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Abstract
<p>LA PRESENTE DIVULGACIÓN PROPORCIONA PROTEÍNAS DE UNIÓN A MRKA, P.EJ., ANTICUERPOS O FRAGMENTOS DE UNIÓN A ANTÍGENO DE LOS MISMOS QUE SE UNEN A MRKA E INDUCEN LA DESTRUCCIÓN OPSONOFAGOCÍTICA DE KLEBSIELLA (P. EJ., KLEBSIELLA PNEUMONIAE). LA PRESENTE DIVULGACIÓN TAMBIÉN PROPORCIONA MÉTODOS DE REDUCCIÓN DE KLEBSIELLA (P. EJ., KLEBSIELLA PNEUMONIAE) O TRATAMIENTO O PREVENCIÓN DE INFECCIÓN POR KLEBSIELLA (P. EJ., KLEBSIELLA PNEUMONIAE) EN UN SUJETO, QUE COMPRENDEN ADMINISTRAR PROTEÍNAS DE UNIÓN A MRKA, P. EJ., ANTICUERPOS O FRAGMENTOS DE UNIÓN A ANTÍGENO DE LOS MISMOS, POLIPÉPTIDOS MRKA, FRAGMENTOS INMUNÓGENOS DE LOS MISMOS, O POLINUCLEÓTIDOS QUE CODIFICAN MRKA O FRAGMENTOS INMUNÓGENOS DE LOS MISMOS AL SUJETO.</p>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562208975P | 2015-08-24 | 2015-08-24 | |
US201562238828P | 2015-10-08 | 2015-10-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2018000357A1 true CL2018000357A1 (es) | 2018-07-20 |
Family
ID=58100831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2018000357A CL2018000357A1 (es) | 2015-08-24 | 2018-02-08 | Polipéptidos mrka, anticuerpos y usos los mismos |
Country Status (16)
Country | Link |
---|---|
US (2) | US20170073397A1 (es) |
EP (1) | EP3341004A4 (es) |
JP (1) | JP2018527924A (es) |
KR (1) | KR20180042300A (es) |
CN (1) | CN107921086A (es) |
AU (1) | AU2016313653A1 (es) |
BR (1) | BR112018003252A2 (es) |
CA (1) | CA2995387A1 (es) |
CL (1) | CL2018000357A1 (es) |
CO (1) | CO2018001985A2 (es) |
HK (1) | HK1252350A1 (es) |
IL (1) | IL257434A (es) |
MX (1) | MX2018001964A (es) |
RU (1) | RU2018107056A (es) |
TW (1) | TW201718626A (es) |
WO (1) | WO2017035154A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201900027XA (en) * | 2016-08-05 | 2019-02-27 | Medimmune Llc | Anti-o2 antibodies and uses thereof |
JP7160484B2 (ja) | 2016-10-19 | 2022-10-25 | メディミューン,エルエルシー | 抗o1抗体およびその使用 |
EP3641828B1 (en) * | 2017-06-23 | 2023-11-22 | Affinivax, Inc. | Immunogenic compositions |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020062010A1 (en) * | 1997-05-02 | 2002-05-23 | Genentech, Inc. | Method for making multispecific antibodies having heteromultimeric and common components |
US7041465B1 (en) * | 1999-08-11 | 2006-05-09 | Washington University | Anti-bacterial compounds directed against pilus biogenesis, adhesion and activity; co-crystals of pilus subunits and methods of use thereof |
WO2001010386A2 (en) * | 1999-08-11 | 2001-02-15 | Washington University | Anti-bacterial compounds directed against pilus biogenesis, adhesion and activity; co-crystals of pilus subunits and methods of use thereof |
AU2004279441B2 (en) * | 2003-10-08 | 2010-07-01 | The Feinstein Institute For Medical Research | Methods and compositions for diagnosis and treatment of B cell chronic lymphocytic leukemia |
CA2654712C (en) * | 2006-06-06 | 2015-05-05 | Crucell Holland B.V. | Human binding molecules having killing activity against staphylococci and uses thereof |
GB0615662D0 (en) * | 2006-08-07 | 2006-09-13 | Affitech As | Antibody |
EP2497779A1 (en) * | 2007-05-02 | 2012-09-12 | Intercell AG | Klebsiella antigens |
GB0915403D0 (en) * | 2009-09-04 | 2009-10-07 | London School Hygiene & Tropical Medicine | Protein glycosylation |
US8961977B2 (en) * | 2010-02-12 | 2015-02-24 | University Of Rochester | Antigenic mimics of discontinuous epitopes of pathogen recognized by broadly neutralizing antibodies |
US20140011691A1 (en) * | 2010-10-26 | 2014-01-09 | Arizona Board of Regents, A Body Corporate of the State of Arizona, Acting for and on Behalf of Az. | Morphology and protein specific reagents as diagnostics for neurodegenerative diseases |
ES2859323T3 (es) * | 2011-11-07 | 2021-10-01 | Medimmune Ltd | Terapias de combinación que usan moléculas de unión anti-Psl y PcrV de Pseudomonas |
-
2016
- 2016-08-23 BR BR112018003252A patent/BR112018003252A2/pt not_active Application Discontinuation
- 2016-08-23 CA CA2995387A patent/CA2995387A1/en not_active Abandoned
- 2016-08-23 CN CN201680047771.3A patent/CN107921086A/zh active Pending
- 2016-08-23 US US15/244,960 patent/US20170073397A1/en not_active Abandoned
- 2016-08-23 EP EP16839995.4A patent/EP3341004A4/en not_active Withdrawn
- 2016-08-23 KR KR1020187007376A patent/KR20180042300A/ko unknown
- 2016-08-23 JP JP2018509904A patent/JP2018527924A/ja active Pending
- 2016-08-23 RU RU2018107056A patent/RU2018107056A/ru not_active Application Discontinuation
- 2016-08-23 TW TW105126946A patent/TW201718626A/zh unknown
- 2016-08-23 MX MX2018001964A patent/MX2018001964A/es unknown
- 2016-08-23 AU AU2016313653A patent/AU2016313653A1/en not_active Abandoned
- 2016-08-23 WO PCT/US2016/048221 patent/WO2017035154A1/en active Application Filing
-
2018
- 2018-02-08 IL IL257434A patent/IL257434A/en unknown
- 2018-02-08 CL CL2018000357A patent/CL2018000357A1/es unknown
- 2018-02-23 CO CONC2018/0001985A patent/CO2018001985A2/es unknown
- 2018-03-29 US US15/940,344 patent/US20190062411A1/en not_active Abandoned
- 2018-09-11 HK HK18111635.8A patent/HK1252350A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
RU2018107056A (ru) | 2019-09-26 |
EP3341004A4 (en) | 2019-05-15 |
CA2995387A1 (en) | 2017-03-02 |
MX2018001964A (es) | 2018-06-19 |
AU2016313653A1 (en) | 2018-04-12 |
BR112018003252A2 (pt) | 2018-09-25 |
TW201718626A (zh) | 2017-06-01 |
US20170073397A1 (en) | 2017-03-16 |
KR20180042300A (ko) | 2018-04-25 |
EP3341004A1 (en) | 2018-07-04 |
JP2018527924A (ja) | 2018-09-27 |
US20190062411A1 (en) | 2019-02-28 |
CN107921086A (zh) | 2018-04-17 |
IL257434A (en) | 2018-04-30 |
WO2017035154A1 (en) | 2017-03-02 |
CO2018001985A2 (es) | 2018-11-22 |
HK1252350A1 (zh) | 2019-05-24 |
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