CL2016002361A1 - Compuestos derivados de azabenzofurano; composición farmacéutica, y su uso como inhibidores de la función de la proteína ns5b del hcv para el tratamiento de la hepatitis c. - Google Patents
Compuestos derivados de azabenzofurano; composición farmacéutica, y su uso como inhibidores de la función de la proteína ns5b del hcv para el tratamiento de la hepatitis c.Info
- Publication number
- CL2016002361A1 CL2016002361A1 CL2016002361A CL2016002361A CL2016002361A1 CL 2016002361 A1 CL2016002361 A1 CL 2016002361A1 CL 2016002361 A CL2016002361 A CL 2016002361A CL 2016002361 A CL2016002361 A CL 2016002361A CL 2016002361 A1 CL2016002361 A1 CL 2016002361A1
- Authority
- CL
- Chile
- Prior art keywords
- azabenzofuran
- hepatitis
- inhibitors
- treatment
- function
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
COMPUESTOS DERIVADOS DE AZABENZOFURANO; COMPOSICIÓN FARMACÉUTICA, Y SU USO COMO INHIBIDORES DE LA FUNCIÓN DE LA PROTEÍNA NS5B DEL HCV PARA EL TRATAMIENTO DE LA HEPATITIS C.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461968763P | 2014-03-21 | 2014-03-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2016002361A1 true CL2016002361A1 (es) | 2017-04-21 |
Family
ID=52808191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2016002361A CL2016002361A1 (es) | 2014-03-21 | 2016-09-20 | Compuestos derivados de azabenzofurano; composición farmacéutica, y su uso como inhibidores de la función de la proteína ns5b del hcv para el tratamiento de la hepatitis c. |
Country Status (18)
Country | Link |
---|---|
US (1) | US9249152B2 (es) |
EP (1) | EP3119785B1 (es) |
JP (1) | JP2017509700A (es) |
KR (1) | KR20160126085A (es) |
CN (1) | CN106459070A (es) |
AR (1) | AR099820A1 (es) |
AU (1) | AU2015231139A1 (es) |
CA (1) | CA2943526A1 (es) |
CL (1) | CL2016002361A1 (es) |
EA (1) | EA201691777A1 (es) |
ES (1) | ES2688554T3 (es) |
IL (1) | IL247830A0 (es) |
MX (1) | MX2016012104A (es) |
PE (1) | PE20161224A1 (es) |
SG (1) | SG11201607750PA (es) |
TW (1) | TW201620914A (es) |
WO (1) | WO2015143255A1 (es) |
ZA (1) | ZA201606478B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015143256A1 (en) * | 2014-03-21 | 2015-09-24 | Bristol-Myers Squibb Company | Cyanoamino (aza)benzofuran compounds for the treatment of hepatitis c |
KR20180086247A (ko) * | 2015-12-07 | 2018-07-30 | 플렉시콘 인코퍼레이티드 | 키나제 조절을 위한 화합물 및 방법과 이들에 대한 징후 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004041201A2 (en) | 2002-11-01 | 2004-05-21 | Viropharma Incorporated | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases |
EP2245023B1 (en) | 2008-02-14 | 2011-12-28 | F. Hoffmann-La Roche AG | Heterocyclic antiviral compounds |
US8048887B2 (en) * | 2008-09-11 | 2011-11-01 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US7994171B2 (en) * | 2008-09-11 | 2011-08-09 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US8198449B2 (en) * | 2008-09-11 | 2012-06-12 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
EP2545050B1 (en) * | 2010-03-10 | 2014-08-13 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis c |
NZ609564A (en) | 2010-10-26 | 2015-06-26 | Presidio Pharmaceuticals Inc | Inhibitors of hepatitis c virus |
-
2015
- 2015-03-20 WO PCT/US2015/021638 patent/WO2015143255A1/en active Application Filing
- 2015-03-20 ES ES15714137.5T patent/ES2688554T3/es active Active
- 2015-03-20 CN CN201580024715.3A patent/CN106459070A/zh active Pending
- 2015-03-20 AR ARP150100859A patent/AR099820A1/es unknown
- 2015-03-20 AU AU2015231139A patent/AU2015231139A1/en not_active Abandoned
- 2015-03-20 US US14/663,497 patent/US9249152B2/en active Active
- 2015-03-20 EP EP15714137.5A patent/EP3119785B1/en not_active Not-in-force
- 2015-03-20 MX MX2016012104A patent/MX2016012104A/es unknown
- 2015-03-20 CA CA2943526A patent/CA2943526A1/en not_active Abandoned
- 2015-03-20 KR KR1020167028891A patent/KR20160126085A/ko unknown
- 2015-03-20 SG SG11201607750PA patent/SG11201607750PA/en unknown
- 2015-03-20 PE PE2016001648A patent/PE20161224A1/es not_active Application Discontinuation
- 2015-03-20 EA EA201691777A patent/EA201691777A1/ru unknown
- 2015-03-20 TW TW104109071A patent/TW201620914A/zh unknown
- 2015-03-20 JP JP2017501122A patent/JP2017509700A/ja active Pending
-
2016
- 2016-09-15 IL IL247830A patent/IL247830A0/en unknown
- 2016-09-20 ZA ZA2016/06478A patent/ZA201606478B/en unknown
- 2016-09-20 CL CL2016002361A patent/CL2016002361A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2017509700A (ja) | 2017-04-06 |
ZA201606478B (en) | 2018-05-30 |
TW201620914A (zh) | 2016-06-16 |
EP3119785A1 (en) | 2017-01-25 |
IL247830A0 (en) | 2016-11-30 |
EP3119785B1 (en) | 2018-08-15 |
WO2015143255A1 (en) | 2015-09-24 |
MX2016012104A (es) | 2016-12-09 |
KR20160126085A (ko) | 2016-11-01 |
ES2688554T3 (es) | 2018-11-05 |
PE20161224A1 (es) | 2016-11-12 |
US20150266886A1 (en) | 2015-09-24 |
SG11201607750PA (en) | 2016-10-28 |
US9249152B2 (en) | 2016-02-02 |
CA2943526A1 (en) | 2015-09-24 |
AR099820A1 (es) | 2016-08-17 |
AU2015231139A1 (en) | 2016-11-03 |
CN106459070A (zh) | 2017-02-22 |
EA201691777A1 (ru) | 2016-12-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2016000493A1 (es) | Inhibidores de polimerasa hcv. | |
CL2016002027A1 (es) | Ciclopropilamina como inhibidor de la lsd1 | |
CL2016002179A1 (es) | Nuevas heteroarildihidropirimidinas 6-fusionadas para el tratamiento y la profilaxis de la infección por virus de la hepatitis b. | |
DOP2017000078A (es) | Indazoles sustituidos con bencilo como inhibidores de bub1. | |
CL2016003398A1 (es) | Compuestos de heteroarilo útiles como inhibidores de enzima activadora de sumo. | |
CO2017004736A2 (es) | Péptidos macrociclicos útiles como inmunomoduladores | |
CL2016000153A1 (es) | Derivados de pirrolamida sustituidos con glioxamida y su uso como medicamentos para el tratamiento de la hepatitis b | |
CO2017005784A2 (es) | Compuestos bicíclicos fusionados para el tratamiento de enfermedades | |
EA201791460A1 (ru) | N4-гидроксицитидин и связанные с ним производные и варианты противовирусного применения | |
CL2016002269A1 (es) | Moduladores alostéricos del núcleo proteico de la hepatitis b. | |
CL2016000952A1 (es) | Derivados de carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b | |
CL2016002735A1 (es) | Compuestos de imidazo[4,5-c]quinolin-2-ona y su uso para tratar cáncer | |
EA201790630A1 (ru) | Способы получения рибозидов | |
CO2017007121A2 (es) | Compuestos bicíclicos fusionados para el tratamiento de enfermedades | |
CL2015001985A1 (es) | Compuestos de tiazolcarboxamidas y piridinacarboxamida, inhibidores de quinasa pim. | |
CL2014002873A1 (es) | Compuestos derivados de pirimidin-amina o triazin-amina, inhibidores de adn-pk; composicion farmaceutica; y su uso para el tratamiento del cancer. | |
CL2016003422A1 (es) | Inhibidores de demetilasa-1 específico de lisina | |
UY34566A (es) | 1,4?dihidropirimidinas 4,4?disustituidas y su uso como medicamentos para el tratamiento de la hepatitis b | |
CL2016001840A1 (es) | Compuestos derivados de pirimidinas fusionadas como inhibidores del complejo p97; composicion farmaceutica y uso en el tratamiento del cancer. | |
CL2016003423A1 (es) | Inhibidores de demetilasa-1 específico de lisina | |
CL2016001973A1 (es) | Derivados de nucleosido sustituidos con 4' -difluorometilo como inhibidores de la replicación de arn de la influenza. | |
CL2015002897A1 (es) | Inhibidores de bace1 | |
CL2016003074A1 (es) | Compuestos derivados de 2-oxi-2-fenil-n-5-pirrolidin-3-ilamino-1,3,4-tiadiazol-2-ilacetamida, inhibidores gls1 composición farmacéutica y su uso para tratar el cáncer. | |
EA201692358A1 (ru) | Производные изоиндолина для применения в лечении вирусной инфекции | |
CL2016002482A1 (es) | Compuestos de azol sustituidos con amida como inhibidores de tnks1 y/o tnks2. |