CL2016001327A1 - Terapia de combinación de anticuerpos anti-mif y quimioterapeuticos (divisional de solicitud 2788-14) - Google Patents

Terapia de combinación de anticuerpos anti-mif y quimioterapeuticos (divisional de solicitud 2788-14)

Info

Publication number
CL2016001327A1
CL2016001327A1 CL2016001327A CL2016001327A CL2016001327A1 CL 2016001327 A1 CL2016001327 A1 CL 2016001327A1 CL 2016001327 A CL2016001327 A CL 2016001327A CL 2016001327 A CL2016001327 A CL 2016001327A CL 2016001327 A1 CL2016001327 A1 CL 2016001327A1
Authority
CL
Chile
Prior art keywords
mif
combination therapy
divisional application
chemotherapeutic antibodies
chemotherapeutic
Prior art date
Application number
CL2016001327A
Other languages
English (en)
Inventor
Randolf Kerschbaumer
Hartmut Ehrlich
Friedrich Scheiflinger
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48625989&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2016001327(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Publication of CL2016001327A1 publication Critical patent/CL2016001327A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
CL2016001327A 2012-04-16 2016-05-31 Terapia de combinación de anticuerpos anti-mif y quimioterapeuticos (divisional de solicitud 2788-14) CL2016001327A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261624964P 2012-04-16 2012-04-16
US201261668932P 2012-07-06 2012-07-06
US201361778094P 2013-03-12 2013-03-12

Publications (1)

Publication Number Publication Date
CL2016001327A1 true CL2016001327A1 (es) 2017-01-06

Family

ID=48625989

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2014002788A CL2014002788A1 (es) 2012-04-16 2014-10-16 Combinación de anticuerpos anti-mif y los quimioterapeuticos gemcitabina, cisplatina y/o doxorubicina; y su uso contra el cancer.
CL2016001327A CL2016001327A1 (es) 2012-04-16 2016-05-31 Terapia de combinación de anticuerpos anti-mif y quimioterapeuticos (divisional de solicitud 2788-14)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2014002788A CL2014002788A1 (es) 2012-04-16 2014-10-16 Combinación de anticuerpos anti-mif y los quimioterapeuticos gemcitabina, cisplatina y/o doxorubicina; y su uso contra el cancer.

Country Status (16)

Country Link
US (1) US20150071942A1 (es)
EP (2) EP2838561A1 (es)
JP (2) JP2015514735A (es)
KR (2) KR20160049047A (es)
CN (2) CN106139143A (es)
AU (1) AU2013202693B2 (es)
BR (1) BR112014025855A8 (es)
CA (1) CA2869990A1 (es)
CL (2) CL2014002788A1 (es)
CO (1) CO7131377A2 (es)
HK (1) HK1206985A1 (es)
IL (2) IL235038A0 (es)
MX (1) MX2014012535A (es)
NZ (1) NZ628363A (es)
RU (2) RU2016117260A (es)
WO (1) WO2013156473A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105452867A (zh) 2012-07-10 2016-03-30 巴克斯特保健股份有限公司 抗-mif的免疫组织化学
AU2015206178A1 (en) * 2014-01-03 2016-07-07 Baxalta GmbH Anti-MIF immunohistochemistry
EP3277718B1 (en) 2015-03-31 2021-03-24 Baxalta GmbH Dosage regimen for anti-mif antibodies
WO2016184886A1 (en) 2015-05-18 2016-11-24 Baxalta GmbH Anti-mif antibodies in the treatment of cancers containing mutant tp53 and/or mutant ras

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1741779A3 (en) * 1993-05-17 2010-03-24 The Picower Institute For Medical Research Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine mediated toxicity
US6080407A (en) * 1993-05-17 2000-06-27 The Picower Institute For Medical Research Diagnostic assays for MIF
US6774227B1 (en) * 1993-05-17 2004-08-10 Cytokine Pharmasciences, Inc. Therapeutic uses of factors which inhibit or neutralize MIF activity
AU2001238677A1 (en) * 2000-02-28 2001-09-12 Idec Pharmaceuticals Corporation Method for preparing anti-mif antibodies
MXPA05007382A (es) * 2003-01-10 2005-11-23 Threshold Pharmaceuticals Inc Tratamiento de cancer con 2-desoxiglucosa.
US8883160B2 (en) * 2004-02-13 2014-11-11 Ibc Pharmaceuticals, Inc. Dock-and-lock (DNL) complexes for therapeutic and diagnostic use
CN101010100A (zh) * 2004-07-02 2007-08-01 纽泰克医药有限公司 癌症的治疗方法
SG153825A1 (en) * 2005-12-16 2009-07-29 Ibc Pharmaceuticals Inc Multivalent immunoglobulin-based bioactive assemblies
CN100457895C (zh) * 2006-05-24 2009-02-04 中国科学院生物物理研究所 鼠抗人巨噬细胞迁移抑制因子单克隆抗体及其应用
US20090220521A1 (en) * 2008-01-04 2009-09-03 Randolf Kerschbaumer Anti MIF Antibodies
CA2787074A1 (en) * 2010-01-19 2011-07-28 Immunomedics, Inc. Novel antibodies that target the insulin-like growth factor type i receptor (igf-1r)
US9465037B2 (en) * 2011-10-07 2016-10-11 Baxalta Incorporated Characterization of CHO-MIF gene and protein, and use thereof
JP2014530360A (ja) * 2011-10-07 2014-11-17 バクスター・ヘルスケヤー・ソシエテ・アノニムＢａｘｔｅｒ Ｈｅａｌｔｈｃａｒｅ ＳＡ 診断マーカーとしてのｏｘＭＩＦ

Also Published As

Publication number Publication date
AU2013202693B2 (en) 2015-01-22
AU2013202693A1 (en) 2013-10-31
RU2014145887A (ru) 2016-06-10
RU2016117260A (ru) 2018-10-23
KR20160049047A (ko) 2016-05-04
US20150071942A1 (en) 2015-03-12
HK1206985A1 (en) 2016-01-22
KR20150027048A (ko) 2015-03-11
JP2016175918A (ja) 2016-10-06
MX2014012535A (es) 2015-04-10
NZ628363A (en) 2017-02-24
EP2838561A1 (en) 2015-02-25
CN104812411A (zh) 2015-07-29
IL245604A0 (en) 2016-06-30
CL2014002788A1 (es) 2015-02-06
IL235038A0 (en) 2014-12-31
BR112014025855A2 (es) 2017-06-20
BR112014025855A8 (pt) 2017-07-25
WO2013156473A1 (en) 2013-10-24
CO7131377A2 (es) 2014-12-01
JP2015514735A (ja) 2015-05-21
RU2016117260A3 (es) 2018-10-23
EP3064221A1 (en) 2016-09-07
CN106139143A (zh) 2016-11-23
CA2869990A1 (en) 2013-10-24

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