CL2014001137A1 - Compuestos derivados de [biciclo[2.2.1]heptano-2,1’-coclobutano]amina, moduladores no competitivos de los receptores nicotinicos; composicion farmaceutica; y metodo para tratar o prevenir una enfermedad o condicion tal como ibs-d, oab, adiccion a la nicotina, dejar de fumar, depresion, trastorno depresivo mayor o hipertension. - Google Patents

Compuestos derivados de [biciclo[2.2.1]heptano-2,1’-coclobutano]amina, moduladores no competitivos de los receptores nicotinicos; composicion farmaceutica; y metodo para tratar o prevenir una enfermedad o condicion tal como ibs-d, oab, adiccion a la nicotina, dejar de fumar, depresion, trastorno depresivo mayor o hipertension.

Info

Publication number
CL2014001137A1
CL2014001137A1 CL2014001137A CL2014001137A CL2014001137A1 CL 2014001137 A1 CL2014001137 A1 CL 2014001137A1 CL 2014001137 A CL2014001137 A CL 2014001137A CL 2014001137 A CL2014001137 A CL 2014001137A CL 2014001137 A1 CL2014001137 A1 CL 2014001137A1
Authority
CL
Chile
Prior art keywords
coclobutane
oab
ibs
bicyclo
hypertension
Prior art date
Application number
CL2014001137A
Other languages
English (en)
Inventor
Srinivasa Rao Akireddy
Yunde Xiao
Daniel Yohannes
Jason Speake
John Genus
Bahwinder Singh Bhatti
Original Assignee
Targacept Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targacept Inc filed Critical Targacept Inc
Publication of CL2014001137A1 publication Critical patent/CL2014001137A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/38Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/44Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CL2014001137A 2011-11-03 2014-04-30 Compuestos derivados de [biciclo[2.2.1]heptano-2,1’-coclobutano]amina, moduladores no competitivos de los receptores nicotinicos; composicion farmaceutica; y metodo para tratar o prevenir una enfermedad o condicion tal como ibs-d, oab, adiccion a la nicotina, dejar de fumar, depresion, trastorno depresivo mayor o hipertension. CL2014001137A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161554998P 2011-11-03 2011-11-03

Publications (1)

Publication Number Publication Date
CL2014001137A1 true CL2014001137A1 (es) 2014-08-18

Family

ID=48193026

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014001137A CL2014001137A1 (es) 2011-11-03 2014-04-30 Compuestos derivados de [biciclo[2.2.1]heptano-2,1’-coclobutano]amina, moduladores no competitivos de los receptores nicotinicos; composicion farmaceutica; y metodo para tratar o prevenir una enfermedad o condicion tal como ibs-d, oab, adiccion a la nicotina, dejar de fumar, depresion, trastorno depresivo mayor o hipertension.

Country Status (14)

Country Link
US (1) US20140288185A1 (es)
EP (1) EP2773609A4 (es)
JP (1) JP2014532708A (es)
KR (1) KR20140098115A (es)
AU (1) AU2012332545A1 (es)
BR (1) BR112014010719A2 (es)
CA (1) CA2853282A1 (es)
CL (1) CL2014001137A1 (es)
IL (1) IL232240A0 (es)
MX (1) MX2014005216A (es)
RU (1) RU2014122338A (es)
SG (1) SG11201401984VA (es)
WO (1) WO2013067105A2 (es)
ZA (1) ZA201403502B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3290215A (en) * 1963-10-29 1966-12-06 Du Pont Use of methanoindanamines as antiviral agents
US3317387A (en) * 1964-05-25 1967-05-02 Du Pont Method of reducing the severity of influenza virus infections
TW200306189A (en) * 2002-03-21 2003-11-16 Merz Pharma Gmbh & Co Kgaa Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists
US8809397B2 (en) * 2010-05-27 2014-08-19 Targacept, Inc. Nicotinic receptor non-competitive antagonists

Also Published As

Publication number Publication date
WO2013067105A2 (en) 2013-05-10
WO2013067105A3 (en) 2013-07-11
EP2773609A2 (en) 2014-09-10
IL232240A0 (en) 2014-06-30
MX2014005216A (es) 2014-08-22
KR20140098115A (ko) 2014-08-07
JP2014532708A (ja) 2014-12-08
ZA201403502B (en) 2015-12-23
AU2012332545A1 (en) 2014-05-29
RU2014122338A (ru) 2015-12-10
SG11201401984VA (en) 2014-05-29
CA2853282A1 (en) 2013-05-10
US20140288185A1 (en) 2014-09-25
BR112014010719A2 (pt) 2017-05-02
EP2773609A4 (en) 2015-06-24

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