CL2013003651A1 - Uso de una composición que comprende un antagonista del receptor de quimiocina c-c tipo 5 (ccr5) para preparar un medicamento útil para tratar una infección por staphylococcus aureus, donde dicha infección por s. aureus es causada por una cepa de s. aureus que expresa luke/d. - Google Patents

Uso de una composición que comprende un antagonista del receptor de quimiocina c-c tipo 5 (ccr5) para preparar un medicamento útil para tratar una infección por staphylococcus aureus, donde dicha infección por s. aureus es causada por una cepa de s. aureus que expresa luke/d.

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Publication number
CL2013003651A1
CL2013003651A1 CL2013003651A CL2013003651A CL2013003651A1 CL 2013003651 A1 CL2013003651 A1 CL 2013003651A1 CL 2013003651 A CL2013003651 A CL 2013003651A CL 2013003651 A CL2013003651 A CL 2013003651A CL 2013003651 A1 CL2013003651 A1 CL 2013003651A1
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CL
Chile
Prior art keywords
aureus
infection
luke
ccr5
strain
Prior art date
Application number
CL2013003651A
Other languages
English (en)
Inventor
Victor J Torres
Francis Alonzo
Derya Unutmaz
Original Assignee
Univ New York
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Publication date
Application filed by Univ New York filed Critical Univ New York
Publication of CL2013003651A1 publication Critical patent/CL2013003651A1/es

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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CL2013003651A 2011-06-19 2013-12-19 Uso de una composición que comprende un antagonista del receptor de quimiocina c-c tipo 5 (ccr5) para preparar un medicamento útil para tratar una infección por staphylococcus aureus, donde dicha infección por s. aureus es causada por una cepa de s. aureus que expresa luke/d. CL2013003651A1 (es)

Applications Claiming Priority (1)

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US201161498606P 2011-06-19 2011-06-19

Publications (1)

Publication Number Publication Date
CL2013003651A1 true CL2013003651A1 (es) 2014-09-26

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CL2013003651A CL2013003651A1 (es) 2011-06-19 2013-12-19 Uso de una composición que comprende un antagonista del receptor de quimiocina c-c tipo 5 (ccr5) para preparar un medicamento útil para tratar una infección por staphylococcus aureus, donde dicha infección por s. aureus es causada por una cepa de s. aureus que expresa luke/d.

Country Status (14)

Country Link
US (3) US8846609B2 (es)
EP (2) EP3135339A1 (es)
JP (1) JP6093760B2 (es)
KR (1) KR20140071318A (es)
CN (1) CN103764228B (es)
AU (1) AU2012273125B2 (es)
BR (1) BR112013032911A2 (es)
CA (1) CA2839558A1 (es)
CL (1) CL2013003651A1 (es)
ES (1) ES2609817T3 (es)
MX (1) MX343589B (es)
MY (1) MY165115A (es)
RU (1) RU2609650C2 (es)
WO (1) WO2012177660A2 (es)

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US9657103B2 (en) 2012-05-02 2017-05-23 New York University Methods of treating and preventing Staphylococcus aureus infections and associated conditions
WO2014205127A2 (en) 2013-06-18 2014-12-24 New York University Cellular factors involved in the cytotoxicity of staphylococcus aureus leukocidins: novel therapeutic targets
CN104744451A (zh) * 2013-12-30 2015-07-01 中国科学院上海药物研究所 一种1-(3-氨基丙基)取代环状胺类化合物、其制备方法、药物组合物及用途
AU2016249837A1 (en) * 2015-04-17 2017-09-28 Arsanis Biosciences Gmbh Anti-staphylococcus aureus antibody combination preparation
CN113648410A (zh) * 2015-06-23 2021-11-16 西托戴恩股份有限公司 Ccr5受体竞争性抑制剂、其应用和治疗方法

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WO2001042208A1 (fr) 1999-12-08 2001-06-14 Teijin Limited Antagonistes du recepteur ccr5 de la cycloamine
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Publication number Publication date
ES2609817T3 (es) 2017-04-24
EP3135339A1 (en) 2017-03-01
US20150056163A1 (en) 2015-02-26
WO2012177660A2 (en) 2012-12-27
NZ619942A (en) 2016-02-26
MY165115A (en) 2018-02-28
CA2839558A1 (en) 2012-12-27
US9480726B2 (en) 2016-11-01
WO2012177660A3 (en) 2013-02-21
EP2720754A4 (en) 2015-04-29
CN103764228B (zh) 2017-09-08
KR20140071318A (ko) 2014-06-11
US20130039885A1 (en) 2013-02-14
MX2013014630A (es) 2014-05-14
EP2720754B1 (en) 2016-10-19
RU2014101489A (ru) 2015-07-27
EP2720754A2 (en) 2014-04-23
JP2014520150A (ja) 2014-08-21
AU2012273125A1 (en) 2014-01-16
AU2012273125B2 (en) 2017-05-25
JP6093760B2 (ja) 2017-03-08
US8846609B2 (en) 2014-09-30
RU2609650C2 (ru) 2017-02-02
BR112013032911A2 (pt) 2017-01-24
MX343589B (es) 2016-11-11
US20170224768A1 (en) 2017-08-10
CN103764228A (zh) 2014-04-30

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