CL2013000483A1 - Agente de formación de imagen que comprende un péptido cíclico de enlace c-met radioetiquetado por 18f; composicion de agente de formación de imagen; precursor util en la formación del péptido cíclico; método para la preparacion del peptido cíclico. - Google Patents

Agente de formación de imagen que comprende un péptido cíclico de enlace c-met radioetiquetado por 18f; composicion de agente de formación de imagen; precursor util en la formación del péptido cíclico; método para la preparacion del peptido cíclico.

Info

Publication number
CL2013000483A1
CL2013000483A1 CL2013000483A CL2013000483A CL2013000483A1 CL 2013000483 A1 CL2013000483 A1 CL 2013000483A1 CL 2013000483 A CL2013000483 A CL 2013000483A CL 2013000483 A CL2013000483 A CL 2013000483A CL 2013000483 A1 CL2013000483 A1 CL 2013000483A1
Authority
CL
Chile
Prior art keywords
cyclic peptide
radiolabelled
met
preparation
image forming
Prior art date
Application number
CL2013000483A
Other languages
English (en)
Spanish (es)
Inventor
Peter Brian Iveson
Rajiv Bhalla
Bard Indrevoll
Gareth Getvoldsen
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of CL2013000483A1 publication Critical patent/CL2013000483A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1833Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nuclear Medicine (AREA)
CL2013000483A 2010-08-18 2013-02-18 Agente de formación de imagen que comprende un péptido cíclico de enlace c-met radioetiquetado por 18f; composicion de agente de formación de imagen; precursor util en la formación del péptido cíclico; método para la preparacion del peptido cíclico. CL2013000483A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1013808.9A GB201013808D0 (en) 2010-08-18 2010-08-18 Peptide radiotracer compositions

Publications (1)

Publication Number Publication Date
CL2013000483A1 true CL2013000483A1 (es) 2014-03-07

Family

ID=42938098

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013000483A CL2013000483A1 (es) 2010-08-18 2013-02-18 Agente de formación de imagen que comprende un péptido cíclico de enlace c-met radioetiquetado por 18f; composicion de agente de formación de imagen; precursor util en la formación del péptido cíclico; método para la preparacion del peptido cíclico.

Country Status (19)

Country Link
US (1) US9533059B2 (enExample)
EP (1) EP2605802B1 (enExample)
JP (1) JP6014592B2 (enExample)
KR (1) KR101853993B1 (enExample)
CN (1) CN103153350B (enExample)
AU (1) AU2011290856B2 (enExample)
BR (1) BR112013003469A2 (enExample)
CA (1) CA2807491C (enExample)
CL (1) CL2013000483A1 (enExample)
ES (1) ES2626410T3 (enExample)
GB (1) GB201013808D0 (enExample)
IL (1) IL224463A (enExample)
MX (1) MX348733B (enExample)
MY (1) MY163136A (enExample)
NZ (1) NZ606466A (enExample)
PH (1) PH12013500270A1 (enExample)
RU (1) RU2594167C2 (enExample)
SG (1) SG187878A1 (enExample)
WO (1) WO2012022676A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201103696D0 (en) 2011-03-04 2011-04-20 Ge Healthcare Ltd Technetium labelled peptides
GB201121914D0 (en) 2011-12-20 2012-02-01 Ge Healthcare Ltd Method for patient selection
GB201209082D0 (en) * 2012-05-24 2012-07-04 Ge Healthcare Ltd Purification method
GB201221266D0 (en) * 2012-11-27 2013-01-09 Ge Healthcare Ltd Aldehyde compositions
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322456D0 (en) * 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
GB201322451D0 (en) * 2013-12-18 2014-02-05 Ge Healthcare Ltd Purification method and compositions
WO2018022603A1 (en) * 2016-07-25 2018-02-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of making 18f-labeled precursors and peptides, labeled c-met binding peptides, and methods of use thereof
GB201804835D0 (en) * 2018-03-26 2018-05-09 Ge Healthcare As Formulation and method of preparation
AU2020291197A1 (en) 2019-06-14 2022-01-27 Edinburgh Molecular Imaging Limited Compounds and methods of use
GB201915206D0 (en) * 2019-10-21 2019-12-04 Ge Healthcare Ltd Use of cyclodextrins as a radiostabilizer
SE2050387A1 (en) * 2020-04-06 2021-10-07 Pvac Medical Tech Ltd Labelled substance and methods of detection of inflammation and infection using said substance
TW202305012A (zh) * 2021-03-22 2023-02-01 日商肽夢想股份有限公司 c-Met 蛋白質結合肽複合物
GB202105950D0 (en) * 2021-04-26 2021-06-09 Ge Healthcare Ltd Analytical HPLC

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
AU2002357388A1 (en) 2001-12-27 2003-07-24 The United States Of America, As Represented By The Department Of Veterans Affairs Monoclonal antibody imaging and therapy of tumors that express met and bind hepatocyte growth factor
US20050214859A1 (en) * 2003-03-03 2005-09-29 Dyax Corp. Peptides that specifically bind HGF receptor (cMet) and uses thereof
GB0305704D0 (en) 2003-03-13 2003-04-16 Amersham Plc Radiofluorination methods
GB0420344D0 (en) * 2004-09-14 2004-10-13 Amersham Plc Diagnostic compounds
CA2656487A1 (en) 2006-07-07 2008-01-17 The Board Of Trustees Of The Leland Stanford Junior University Selective caspase inhibitors
GB0615211D0 (en) 2006-07-31 2006-09-06 Ge Healthcare Uk Ltd Asymmetric flouro-substituted polymethine dyes
MX2009002492A (es) 2006-09-08 2009-08-28 Bayer Schering Pharma Ag Agentes que comprenden compuestos marcados con 18f y metodos relacionados.
US8247534B2 (en) 2006-12-13 2012-08-21 Ge Healthcare As Synthesis of radiofluorinated peptide using microwave activation technology
EP2114464A2 (en) * 2006-12-28 2009-11-11 GE Healthcare AS Radiofluorination methods
BRPI0721424A2 (pt) 2007-03-01 2014-03-25 Bayer Schering Pharma Ag Métodos de radiofluoração
RU2475266C2 (ru) 2007-05-16 2013-02-20 ДжиИ Хелткер АС Оптические агенты визуализации
GB0718957D0 (en) 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
GB0718967D0 (en) 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
GB0716897D0 (en) 2007-08-30 2007-10-10 Univ Muenchen Tech Cancer imaging and treatment
GB0803477D0 (en) * 2008-02-26 2008-04-02 Ge Healthcare As Therapy selection method

Also Published As

Publication number Publication date
MX2013001939A (es) 2013-03-18
AU2011290856A1 (en) 2013-03-14
KR20130135242A (ko) 2013-12-10
RU2594167C2 (ru) 2016-08-10
BR112013003469A2 (pt) 2016-06-21
MX348733B (es) 2017-06-27
JP2013540702A (ja) 2013-11-07
CA2807491C (en) 2019-06-04
AU2011290856B2 (en) 2014-12-04
NZ606466A (en) 2014-11-28
GB201013808D0 (en) 2010-09-29
CN103153350A (zh) 2013-06-12
KR101853993B1 (ko) 2018-05-02
WO2012022676A1 (en) 2012-02-23
US9533059B2 (en) 2017-01-03
SG187878A1 (en) 2013-03-28
EP2605802B1 (en) 2017-04-26
EP2605802A1 (en) 2013-06-26
US20130149241A1 (en) 2013-06-13
JP6014592B2 (ja) 2016-10-25
CN103153350B (zh) 2016-06-29
RU2013105491A (ru) 2014-09-27
ES2626410T3 (es) 2017-07-25
CA2807491A1 (en) 2012-02-23
IL224463A (en) 2016-05-31
PH12013500270A1 (en) 2013-04-01
MY163136A (en) 2017-08-15

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