CA2807491C - F18 c-met binding cyclic peptide radiotracers and compositions thereof - Google Patents
F18 c-met binding cyclic peptide radiotracers and compositions thereof Download PDFInfo
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- CA2807491C CA2807491C CA2807491A CA2807491A CA2807491C CA 2807491 C CA2807491 C CA 2807491C CA 2807491 A CA2807491 A CA 2807491A CA 2807491 A CA2807491 A CA 2807491A CA 2807491 C CA2807491 C CA 2807491C
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- gly
- peptide
- cys
- cyclic peptide
- met binding
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
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- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nuclear Medicine (AREA)
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| GB1013808.9 | 2010-08-18 | ||
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| PCT/EP2011/063890 WO2012022676A1 (en) | 2010-08-18 | 2011-08-11 | Peptide radiotracer compositions |
Publications (2)
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| CA2807491A1 CA2807491A1 (en) | 2012-02-23 |
| CA2807491C true CA2807491C (en) | 2019-06-04 |
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| CA2807491A Active CA2807491C (en) | 2010-08-18 | 2011-08-11 | F18 c-met binding cyclic peptide radiotracers and compositions thereof |
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| ES (1) | ES2626410T3 (enExample) |
| GB (1) | GB201013808D0 (enExample) |
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| PH (1) | PH12013500270A1 (enExample) |
| RU (1) | RU2594167C2 (enExample) |
| SG (1) | SG187878A1 (enExample) |
| WO (1) | WO2012022676A1 (enExample) |
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| GB201103696D0 (en) * | 2011-03-04 | 2011-04-20 | Ge Healthcare Ltd | Technetium labelled peptides |
| GB201121914D0 (en) | 2011-12-20 | 2012-02-01 | Ge Healthcare Ltd | Method for patient selection |
| GB201209082D0 (en) * | 2012-05-24 | 2012-07-04 | Ge Healthcare Ltd | Purification method |
| GB201221266D0 (en) * | 2012-11-27 | 2013-01-09 | Ge Healthcare Ltd | Aldehyde compositions |
| GB201314936D0 (en) | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| GB201322451D0 (en) * | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Purification method and compositions |
| GB201322456D0 (en) * | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| US20190151483A1 (en) * | 2016-07-25 | 2019-05-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv | Methods of making 18f-labeled precursors and peptides, labeled c-met binding peptides, and methods of use thereof |
| GB201804835D0 (en) * | 2018-03-26 | 2018-05-09 | Ge Healthcare As | Formulation and method of preparation |
| CN114222592A (zh) | 2019-06-14 | 2022-03-22 | 爱丁堡分子成像有限公司 | 化合物和使用方法 |
| GB201915206D0 (en) * | 2019-10-21 | 2019-12-04 | Ge Healthcare Ltd | Use of cyclodextrins as a radiostabilizer |
| SE2050387A1 (en) * | 2020-04-06 | 2021-10-07 | Pvac Medical Tech Ltd | Labelled substance and methods of detection of inflammation and infection using said substance |
| TW202509086A (zh) * | 2021-03-22 | 2025-03-01 | 日商肽夢想股份有限公司 | c－Met蛋白質結合肽複合物 |
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| US5961955A (en) * | 1997-06-03 | 1999-10-05 | Coulter Pharmaceutical, Inc. | Radioprotectant for peptides labeled with radioisotope |
| WO2003057155A2 (en) | 2001-12-27 | 2003-07-17 | Van Andel Research Institute | Monoclonal antibody imaging and therapy of tumors that express met and bind hepatocyte growth factor |
| ES2396368T3 (es) * | 2003-03-03 | 2013-02-21 | Dyax Corporation | Péptidos que se unen específicamente al receptor del HGF (CMET) y usos de los mismos |
| GB0305704D0 (en) * | 2003-03-13 | 2003-04-16 | Amersham Plc | Radiofluorination methods |
| GB0420344D0 (en) * | 2004-09-14 | 2004-10-13 | Amersham Plc | Diagnostic compounds |
| US20100068150A1 (en) | 2006-07-07 | 2010-03-18 | The Board Of Trustees Of The Leland Stanford Junior University | Selective Caspase Inhibitors |
| GB0615211D0 (en) | 2006-07-31 | 2006-09-06 | Ge Healthcare Uk Ltd | Asymmetric flouro-substituted polymethine dyes |
| US8557776B2 (en) | 2006-09-08 | 2013-10-15 | Bayer Pharma AG | Compounds and methods for 18F labeled agents |
| WO2008072976A2 (en) | 2006-12-13 | 2008-06-19 | Ge Healthcare As | Synthesis of a radiofluorinated peptide using microwave activation technology |
| US8216548B2 (en) * | 2006-12-28 | 2012-07-10 | Ge Healthcare As | Radiofluorination methods |
| EA200901142A1 (ru) * | 2007-03-01 | 2010-04-30 | Байер Шеринг Фарма Акциенгезельшафт | 18f фторбензоильные меченые биологически активные соединения в качестве диагностических визуализирующих средств, а также бензотриазол-1-илоксибензоильные, 2,5-(диоксопирролидин-1-илокси)бензоильные и триметиламмониобензоильные предшественники |
| CN101848734B (zh) | 2007-05-16 | 2013-08-28 | 通用电气医疗集团股份有限公司 | 用于成像的经标记的iigf结合肽 |
| GB0718967D0 (en) * | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Peptide imaging agents |
| GB0718957D0 (en) | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Optical imaging agents |
| GB0716897D0 (en) | 2007-08-30 | 2007-10-10 | Univ Muenchen Tech | Cancer imaging and treatment |
| GB0803477D0 (en) | 2008-02-26 | 2008-04-02 | Ge Healthcare As | Therapy selection method |
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- 2011-08-11 NZ NZ606466A patent/NZ606466A/en unknown
- 2011-08-11 ES ES11744007.3T patent/ES2626410T3/es active Active
- 2011-08-11 CA CA2807491A patent/CA2807491C/en active Active
- 2011-08-11 EP EP11744007.3A patent/EP2605802B1/en active Active
- 2011-08-11 RU RU2013105491/04A patent/RU2594167C2/ru active
- 2011-08-11 AU AU2011290856A patent/AU2011290856B2/en active Active
- 2011-08-11 PH PH1/2013/500270A patent/PH12013500270A1/en unknown
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- 2013-02-18 CL CL2013000483A patent/CL2013000483A1/es unknown
Also Published As
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|---|---|
| PH12013500270A1 (en) | 2013-04-01 |
| EP2605802B1 (en) | 2017-04-26 |
| US9533059B2 (en) | 2017-01-03 |
| EP2605802A1 (en) | 2013-06-26 |
| MX348733B (es) | 2017-06-27 |
| KR20130135242A (ko) | 2013-12-10 |
| JP2013540702A (ja) | 2013-11-07 |
| US20130149241A1 (en) | 2013-06-13 |
| MX2013001939A (es) | 2013-03-18 |
| CL2013000483A1 (es) | 2014-03-07 |
| WO2012022676A1 (en) | 2012-02-23 |
| AU2011290856B2 (en) | 2014-12-04 |
| CN103153350A (zh) | 2013-06-12 |
| IL224463A (en) | 2016-05-31 |
| GB201013808D0 (en) | 2010-09-29 |
| BR112013003469A2 (pt) | 2016-06-21 |
| JP6014592B2 (ja) | 2016-10-25 |
| RU2013105491A (ru) | 2014-09-27 |
| CA2807491A1 (en) | 2012-02-23 |
| NZ606466A (en) | 2014-11-28 |
| SG187878A1 (en) | 2013-03-28 |
| MY163136A (en) | 2017-08-15 |
| CN103153350B (zh) | 2016-06-29 |
| ES2626410T3 (es) | 2017-07-25 |
| AU2011290856A1 (en) | 2013-03-14 |
| RU2594167C2 (ru) | 2016-08-10 |
| KR101853993B1 (ko) | 2018-05-02 |
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