CH85679A - Process for the preparation of a therapeutically valuable derivative of p-aminophenol. - Google Patents

Process for the preparation of a therapeutically valuable derivative of p-aminophenol.

Info

Publication number
CH85679A
CH85679A CH85679DA CH85679A CH 85679 A CH85679 A CH 85679A CH 85679D A CH85679D A CH 85679DA CH 85679 A CH85679 A CH 85679A
Authority
CH
Switzerland
Prior art keywords
aminophenol
preparation
therapeutically valuable
derivative
valuable derivative
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH85679A publication Critical patent/CH85679A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Description

  

  Verfahren zur     Darstellung    eine'     therapeutisch    wertvollen Derivates des     p-Amino-          phenols.       erstarrt kristallinisch und     wird    aus     Wasser          uinkristallisiei-t.    Er besitzt die in der Haupt:       auineldung    beschriebenen Eigenschaften.  



  Statt     Allylbromid    können andere     Allylie-          rungsmittel,    zum Beispiel andere     Allylhalo-          genide,    verwendet werden.    Es wurde gefunden, dass man zu dem in  der Patentschrift     1\'r.    78044     beschriebenen          p-Lactylaminopheiiolally        läthei,    auch gelangen  kann, wenn man     Lactyl-p-aminophenol    mit       allylierenden    Mitteln behandelt.  



       Beispiel     179 Teile     Lactyl-p-aminophenol    werden  in 300 Teilen Alkohol gelöst und mit 121  Teilen     Allylbromid    versetzt. Man fügt hierauf  eine     Lösung    von 56 Teilen     Ätzkali    in 200  Teilen Alkohol hinzu und kocht während  48 Stunden am     Rückflusskühler.    Man filtriert  hierauf vom ausgeschiedenen Bromkali ab,  destilliert den grössten Teil des Alkohols ab  und versetzt den Rückstand mit Wasser. Der  entstandene     Lactyl-p-aminopheriolallyläther  



  Process for the preparation of a 'therapeutically valuable derivative of p-aminophenol. solidifies in a crystalline manner and becomes uncrystallized from water. It has the properties described in the main message.



  Instead of allyl bromide, other allylating agents, for example other allyl halides, can be used. It has been found that to the one described in patent specification 1 \ 'r. 78044 described p-Lactylaminopheiiolally läthei, can also get if you treat lactyl-p-aminophenol with allylating agents.



       Example 179 parts of lactyl-p-aminophenol are dissolved in 300 parts of alcohol, and 121 parts of allyl bromide are added. A solution of 56 parts of caustic potash in 200 parts of alcohol is then added and the mixture is refluxed for 48 hours. The precipitated potassium bromide is then filtered off, most of the alcohol is distilled off and water is added to the residue. The resulting lactyl-p-aminopheriol allyl ether

Claims (1)

PATENTANSPILUCII Verfahren zur Darstellung eines therapeu tisch wertvollen Derivates des p-Aminophenols, dadurch gekennzeichnet, dar man Lactyl- p-amiriophenol mit allylierenden Mitteln be handelt. PATENTANSPILUCII Process for the preparation of a therapeutically valuable derivative of p-aminophenol, characterized in that lactyl-p-amiriophenol is treated with allylating agents.
CH85679D 1917-11-17 1917-11-17 Process for the preparation of a therapeutically valuable derivative of p-aminophenol. CH85679A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH85679T 1917-11-17
CH76619T 1917-11-17

Publications (1)

Publication Number Publication Date
CH85679A true CH85679A (en) 1920-07-01

Family

ID=25701876

Family Applications (1)

Application Number Title Priority Date Filing Date
CH85679D CH85679A (en) 1917-11-17 1917-11-17 Process for the preparation of a therapeutically valuable derivative of p-aminophenol.

Country Status (1)

Country Link
CH (1) CH85679A (en)

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