CH700067B8 - Tertiary alkyl esters of (E, Z) -11- (3-dimethylaminopropylidene) -6,11-dihydrodibenzo [b, e] oxepin-2-acetic acid and process for their preparation. - Google Patents
Tertiary alkyl esters of (E, Z) -11- (3-dimethylaminopropylidene) -6,11-dihydrodibenzo [b, e] oxepin-2-acetic acid and process for their preparation. Download PDFInfo
- Publication number
- CH700067B8 CH700067B8 CH00490/10A CH4902010A CH700067B8 CH 700067 B8 CH700067 B8 CH 700067B8 CH 00490/10 A CH00490/10 A CH 00490/10A CH 4902010 A CH4902010 A CH 4902010A CH 700067 B8 CH700067 B8 CH 700067B8
- Authority
- CH
- Switzerland
- Prior art keywords
- dimethylaminopropylidene
- dihydrodibenzo
- oxepin
- preparation
- acetic acid
- Prior art date
Links
- 125000005907 alkyl ester group Chemical group 0.000 title 1
- ZGNHLWKYNFSKCD-UHFFFAOYSA-N Dibenzoxepine Chemical class O1C=CC2=CC=CC=C2C2=CC=CC=C12 ZGNHLWKYNFSKCD-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000012024 dehydrating agents Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Dibenzoxepinderivat, dargestellt durch die Formel [I]: worin R 1 , R 2 und R 3 je unabhängig voneinander eine Alkylgruppe mit 1 bis 2 Kohlenstoffatomen bedeuten, wird mit einem dehydratisierenden Agens umgesetzt.Dibenzoxepine derivative represented by the formula [I]: wherein R 1, R 2 and R 3 each independently represents an alkyl group having 1 to 2 carbon atoms is reacted with a dehydrating agent.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007262591A JP5248078B2 (en) | 2007-10-05 | 2007-10-05 | Method for producing dibenzooxepin compound |
PCT/JP2008/067982 WO2009044838A1 (en) | 2007-10-05 | 2008-09-26 | Method for producing dibenzoxepin compound |
Publications (2)
Publication Number | Publication Date |
---|---|
CH700067B1 CH700067B1 (en) | 2012-03-15 |
CH700067B8 true CH700067B8 (en) | 2012-04-30 |
Family
ID=40526261
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH00490/10A CH700067B8 (en) | 2007-10-05 | 2008-09-26 | Tertiary alkyl esters of (E, Z) -11- (3-dimethylaminopropylidene) -6,11-dihydrodibenzo [b, e] oxepin-2-acetic acid and process for their preparation. |
CH01764/11A CH703810B8 (en) | 2007-10-05 | 2008-09-26 | Process for the preparation of a dibenzoxepin compound. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH01764/11A CH703810B8 (en) | 2007-10-05 | 2008-09-26 | Process for the preparation of a dibenzoxepin compound. |
Country Status (5)
Country | Link |
---|---|
JP (1) | JP5248078B2 (en) |
CN (1) | CN101815709B (en) |
CH (2) | CH700067B8 (en) |
ES (1) | ES2344291B1 (en) |
WO (1) | WO2009044838A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011033532A1 (en) | 2009-09-17 | 2011-03-24 | Indoco Remedies Limited | Process for preparation of olopatadine hydrochloride |
CN107488161A (en) * | 2016-06-13 | 2017-12-19 | 江苏吉贝尔药业股份有限公司 | A kind of light method for transformation of olopatadine N-butyl isomers |
CN112142710B (en) * | 2019-06-26 | 2024-07-12 | 住友化学株式会社 | Method for producing ester compound |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6310784A (en) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | Dibenz(b,e)oxepin derivative, antiallergic agent and anti-inflammatory agent |
JPH11279158A (en) * | 1998-02-09 | 1999-10-12 | Pfizer Prod Inc | Production of quinazoline-4-one derivative |
ES2253996B1 (en) * | 2004-07-28 | 2007-08-16 | Urquima, S.A. | PROCEDURE FOR THE PREPARATION OF ACID 11 - ((Z) -3- (DIMETHYLAMINE) PROPILIDEN) -6,11-DIHYDRODIBENZ (B, E) OXEPINACETIC. |
WO2007105234A2 (en) * | 2006-03-14 | 2007-09-20 | Usv Limited | A PROCESS FOR THE PREPARATION OF ISOMERS OF 11-[3-(DIMETHYLAMINO)PROPYLIDENE]-6, 11-DIHYDRODIBENZ [b, e] OXEPIN-2-ACETIC ACID HYDROCHLORIDE AND POLYMORPHS THEREOF |
-
2007
- 2007-10-05 JP JP2007262591A patent/JP5248078B2/en active Active
-
2008
- 2008-09-26 WO PCT/JP2008/067982 patent/WO2009044838A1/en active Application Filing
- 2008-09-26 CH CH00490/10A patent/CH700067B8/en not_active IP Right Cessation
- 2008-09-26 CH CH01764/11A patent/CH703810B8/en not_active IP Right Cessation
- 2008-09-26 CN CN200880109972.7A patent/CN101815709B/en active Active
- 2008-09-26 ES ES201090015A patent/ES2344291B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN101815709A (en) | 2010-08-25 |
JP5248078B2 (en) | 2013-07-31 |
ES2344291A1 (en) | 2010-08-23 |
CH700067B1 (en) | 2012-03-15 |
CH703810B1 (en) | 2012-03-30 |
JP2009091290A (en) | 2009-04-30 |
WO2009044838A1 (en) | 2009-04-09 |
CH703810B8 (en) | 2012-06-15 |
CN101815709B (en) | 2015-09-02 |
ES2344291B1 (en) | 2011-05-13 |
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