CH648414A5 - Antienzym-homogen-kompetitivbindungs-test. - Google Patents

Antienzym-homogen-kompetitivbindungs-test. Download PDF

Info

Publication number
CH648414A5
CH648414A5 CH7673/78A CH767378A CH648414A5 CH 648414 A5 CH648414 A5 CH 648414A5 CH 7673/78 A CH7673/78 A CH 7673/78A CH 767378 A CH767378 A CH 767378A CH 648414 A5 CH648414 A5 CH 648414A5
Authority
CH
Switzerland
Prior art keywords
enzyme
ligand
inhibitor
bound
receptor
Prior art date
Application number
CH7673/78A
Other languages
German (de)
English (en)
Inventor
Robert A Yoshida
Edward T Maggio
Robert F Zuk
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/815,487 external-priority patent/US4233401A/en
Priority claimed from US05/815,632 external-priority patent/US4208479A/en
Application filed by Syva Co filed Critical Syva Co
Publication of CH648414A5 publication Critical patent/CH648414A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016Oximes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CH7673/78A 1977-07-14 1978-07-14 Antienzym-homogen-kompetitivbindungs-test. CH648414A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/815,487 US4233401A (en) 1977-07-14 1977-07-14 Antienzyme homogeneous competitive binding assay
US05/815,632 US4208479A (en) 1977-07-14 1977-07-14 Label modified immunoassays

Publications (1)

Publication Number Publication Date
CH648414A5 true CH648414A5 (de) 1985-03-15

Family

ID=27123960

Family Applications (1)

Application Number Title Priority Date Filing Date
CH7673/78A CH648414A5 (de) 1977-07-14 1978-07-14 Antienzym-homogen-kompetitivbindungs-test.

Country Status (7)

Country Link
JP (1) JPS5420134A (enrdf_load_stackoverflow)
AU (1) AU518002B2 (enrdf_load_stackoverflow)
CH (1) CH648414A5 (enrdf_load_stackoverflow)
DE (1) DE2830862A1 (enrdf_load_stackoverflow)
GB (1) GB2001172B (enrdf_load_stackoverflow)
IT (1) IT1105734B (enrdf_load_stackoverflow)
NL (1) NL7807607A (enrdf_load_stackoverflow)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
US4287300A (en) * 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
DE3006709A1 (de) * 1980-02-22 1981-08-27 Hans A. Dipl.-Chem. Dr. 8000 München Thoma Homogenes verfahren zur kompetitiven bestimmung von liganden
NZ199286A (en) * 1980-12-22 1986-05-09 Commw Serum Lab Commission A method of detecting antibodies or an antigenic or haptenic substance in a sample
DE3100062A1 (de) * 1981-01-02 1982-08-05 Hans A. Dipl.-Chem. Dr. 8000 München Thoma Homogenes verfahren zur bestimmung von liganden
DE3100061A1 (de) * 1981-01-02 1982-08-05 Hans A. Dipl.-Chem. Dr. 8000 München Thoma Verfahren zur bestimmung von liganden mittels kompetitionsreaktion
GB2102946B (en) * 1981-06-30 1984-11-28 Wellcome Found Enzyme immunoassay
JPS5888238U (ja) * 1981-11-30 1983-06-15 大日本スクリ−ン製造株式会社 現像機の感材送り込み装置
JPS58122459A (ja) * 1982-01-14 1983-07-21 Yatoron:Kk 酵素の会合を利用した測定方法
IL67289A (en) * 1982-03-18 1985-12-31 Miles Lab Homogeneous immunoassay with labeled monoclonal anti-analyte
AU574646B2 (en) * 1982-07-19 1988-07-14 Cooperbiomedical Inc. Enzyme assay method
FR2542871B1 (fr) * 1983-03-15 1986-05-16 Pasteur Institut Procede de dosage en phase heterogene de substances biologiques antigeniques, mettant en oeuvre des conjugues hybrides d'anticorps et reactifs pour sa mise en oeuvre
US4828981A (en) * 1983-08-24 1989-05-09 Synbiotics Corporation Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents
IT1199088B (it) * 1984-03-09 1988-12-30 Miles Italiana Saggio di legame specifico mediante impiego di anti-g6pdh come marcante
US4837395A (en) * 1985-05-10 1989-06-06 Syntex (U.S.A.) Inc. Single step heterogeneous assay
JPS62249063A (ja) * 1986-04-22 1987-10-30 Konika Corp 分析素子
US4835099A (en) * 1986-11-20 1989-05-30 Becton, Dickinson And Company Signal enhancement in immunoassay by modulation of enzymatic catalysis
US5137804A (en) * 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
AU2016261939A1 (en) * 2015-05-12 2018-01-04 The General Hospital Corporation D/B/A Massachusetts General Hospital Autoantigens for diagnosis of rheumatoid arthritis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay

Also Published As

Publication number Publication date
AU3800278A (en) 1980-01-17
NL7807607A (nl) 1979-01-16
DE2830862C2 (enrdf_load_stackoverflow) 1988-06-01
GB2001172B (en) 1982-01-27
DE2830862A1 (de) 1979-02-01
JPS631544B2 (enrdf_load_stackoverflow) 1988-01-13
AU518002B2 (en) 1981-09-10
IT1105734B (it) 1985-11-04
GB2001172A (en) 1979-01-24
IT7850259A0 (it) 1978-07-12
JPS5420134A (en) 1979-02-15

Similar Documents

Publication Publication Date Title
CH648414A5 (de) Antienzym-homogen-kompetitivbindungs-test.
US4220722A (en) Method for conjugating to polyamino compounds employing haloacyl groups and compositions prepared thereby
US4174384A (en) Fluorescence quenching with immunological pairs in immunoassays
US4272506A (en) Purification of reagents by disulfide immobilization
US4261968A (en) Fluorescence quenching with immunological pairs in immunoassays
US4199559A (en) Fluorescence quenching with immunological pairs in immunoassays
US4287300A (en) Charge effects in enzyme immunoassays
US4233401A (en) Antienzyme homogeneous competitive binding assay
US3996345A (en) Fluorescence quenching with immunological pairs in immunoassays
US4208479A (en) Label modified immunoassays
US4281061A (en) Double antibody for enhanced sensitivity in immunoassay
US4351760A (en) Novel alkyl substituted fluorescent compounds and polyamino acid conjugates
US4160645A (en) Catalyst mediated competitive protein binding assay
CA1111763A (en) Lipophilic particles non-covalently bonded to label and ligand for binding assay
US5545834A (en) Chemiluminescent compounds and methods of use
DE69316757T2 (de) Photoaktivierbare chemiluminizierende matrices
US4481136A (en) Alkyl substituted fluorescent compounds and conjugates
US4043872A (en) Polyiodothyronine immunoassay
JPS6145778B2 (enrdf_load_stackoverflow)
JPS6337347B2 (enrdf_load_stackoverflow)
US4341758A (en) Immunochemical assay reagent for the determination of haptens, and assay method therewith
US4043989A (en) Oxazepam derivatives for immunoassay reagents
DE69132238T2 (de) Verfahren zur Stabilisierung von Enzym-Konjugaten
CH641570A5 (en) Process for the determination of an immunologically active material and reagent for carrying out this process
US4328311A (en) Enzyme-aminoglycoside conjugates

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased