CH646964A5 - 2-guanidinothiazol-derivate. - Google Patents

2-guanidinothiazol-derivate. Download PDF

Info

Publication number
CH646964A5
CH646964A5 CH279381A CH279381A CH646964A5 CH 646964 A5 CH646964 A5 CH 646964A5 CH 279381 A CH279381 A CH 279381A CH 279381 A CH279381 A CH 279381A CH 646964 A5 CH646964 A5 CH 646964A5
Authority
CH
Switzerland
Prior art keywords
guanidino
optionally substituted
phenyl
acid
thiazole
Prior art date
Application number
CH279381A
Other languages
German (de)
English (en)
Inventor
Kentaro Hirai
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of CH646964A5 publication Critical patent/CH646964A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH279381A 1980-04-29 1981-04-29 2-guanidinothiazol-derivate. CH646964A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14494680A 1980-04-29 1980-04-29

Publications (1)

Publication Number Publication Date
CH646964A5 true CH646964A5 (de) 1984-12-28

Family

ID=22510873

Family Applications (1)

Application Number Title Priority Date Filing Date
CH279381A CH646964A5 (de) 1980-04-29 1981-04-29 2-guanidinothiazol-derivate.

Country Status (16)

Country Link
JP (1) JPS574977A (US06815460-20041109-C00097.png)
AR (1) AR231538A1 (US06815460-20041109-C00097.png)
AU (1) AU540239B2 (US06815460-20041109-C00097.png)
BE (1) BE888602A (US06815460-20041109-C00097.png)
CH (1) CH646964A5 (US06815460-20041109-C00097.png)
DE (1) DE3116890A1 (US06815460-20041109-C00097.png)
DK (1) DK188881A (US06815460-20041109-C00097.png)
ES (1) ES8206501A1 (US06815460-20041109-C00097.png)
FR (1) FR2481280A1 (US06815460-20041109-C00097.png)
GB (1) GB2076397B (US06815460-20041109-C00097.png)
IE (1) IE51151B1 (US06815460-20041109-C00097.png)
IL (1) IL62747A (US06815460-20041109-C00097.png)
IT (1) IT1146750B (US06815460-20041109-C00097.png)
NL (1) NL8102099A (US06815460-20041109-C00097.png)
NZ (1) NZ196923A (US06815460-20041109-C00097.png)
SE (1) SE452462B (US06815460-20041109-C00097.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531705B1 (fr) * 1982-08-13 1986-12-05 Sanofi Sa Amidobenzamides, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant
US4501747A (en) * 1982-05-10 1985-02-26 Sanofi Certain amide derivatives of 2-guanidino-thiazoles and compositions containing same
JPS59104370A (ja) * 1982-12-03 1984-06-16 Kotobuki Seiyaku Kk チアゾ−ル誘導体及びその製造方法
AU563072B2 (en) * 1983-04-26 1987-06-25 Shionogi & Co., Ltd. 2-guanidino-4-hydroxymethylthiazole and derivitives thereof
US4680300A (en) * 1985-01-10 1987-07-14 Syntex (U.S.A.) Inc. Anti-inflammatory guanidines
US4837316A (en) * 1985-08-29 1989-06-06 Fujirebio Kabushiki Kaisha Alkylamide derivatives with H2 -receptor antagonistic and cytoprotective action
EP0385525B1 (en) * 1989-03-03 1994-04-13 Akzo Nv Aminoethylthiazole and aminoethyloxazole derivatives.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186965A (en) * 1977-04-20 1980-02-21 Ici Ltd Guanidino derivatives and pharmaceutical compositions
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
JPS54132566A (en) * 1978-01-18 1979-10-15 Ici Ltd Guanidine derivative*its manufacture and secretion controlling pharmaceutical composition containing it
US4309435A (en) * 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
EP0010893B1 (en) * 1978-10-16 1984-02-08 Imperial Chemical Industries Plc Antisecretory branched-chain heterocyclic guanidine derivatives, processes for their manufacture, intermediates, and pharmaceutical compositions containing said derivatives
DE3069889D1 (en) * 1979-01-18 1985-02-14 Ici Plc Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
PH16099A (en) * 1979-03-06 1983-06-24 Yamanouchi Pharma Co Ltd Guanidinothiazole compounds,process for preparing them and medical composition containing them
GR71929B (US06815460-20041109-C00097.png) * 1979-11-13 1983-08-19 Ici Ltd
JPS5754177A (ja) * 1980-09-19 1982-03-31 Teikoku Hormone Mfg Co Ltd Chikanchiazoorujudotai
JPS57102852A (en) * 1980-12-19 1982-06-26 Shionogi & Co Ltd Dicarboxylic acid diamide

Also Published As

Publication number Publication date
IE810956L (en) 1981-10-29
FR2481280B1 (US06815460-20041109-C00097.png) 1983-10-28
IT8167585A0 (it) 1981-04-29
AR231538A1 (es) 1984-12-28
AU540239B2 (en) 1984-11-08
IL62747A (en) 1984-10-31
DK188881A (da) 1981-10-30
ES501736A0 (es) 1982-08-16
IL62747A0 (en) 1981-06-29
DE3116890A1 (de) 1982-03-04
SE8102683L (sv) 1981-10-30
NZ196923A (en) 1983-12-16
ES8206501A1 (es) 1982-08-16
FR2481280A1 (fr) 1981-10-30
SE452462B (sv) 1987-11-30
JPS574977A (en) 1982-01-11
JPH027952B2 (US06815460-20041109-C00097.png) 1990-02-21
BE888602A (fr) 1981-10-28
AU6996681A (en) 1981-11-05
IE51151B1 (en) 1986-10-15
NL8102099A (nl) 1981-11-16
GB2076397B (en) 1984-02-08
GB2076397A (en) 1981-12-02
IT1146750B (it) 1986-11-19

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PL Patent ceased