CH633557A5 - Process for the preparation of 7-acylamino-3-(sulphomethylthiadiazolylthiomethyl)- or -(sulphomethyltriazolylthiomethyl)-3-cephem-4-carboxylic acids, and their use. - Google Patents

Process for the preparation of 7-acylamino-3-(sulphomethylthiadiazolylthiomethyl)- or -(sulphomethyltriazolylthiomethyl)-3-cephem-4-carboxylic acids, and their use. Download PDF

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Publication number
CH633557A5
CH633557A5 CH1166877A CH1166877A CH633557A5 CH 633557 A5 CH633557 A5 CH 633557A5 CH 1166877 A CH1166877 A CH 1166877A CH 1166877 A CH1166877 A CH 1166877A CH 633557 A5 CH633557 A5 CH 633557A5
Authority
CH
Switzerland
Prior art keywords
cephem
sulfomethyl
thiol
acylamino
preparation
Prior art date
Application number
CH1166877A
Other languages
German (de)
English (en)
Inventor
David Alan Berges
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/726,378 external-priority patent/US4079134A/en
Priority claimed from US05/726,377 external-priority patent/US4083975A/en
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of CH633557A5 publication Critical patent/CH633557A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH1166877A 1976-09-24 1977-09-23 Process for the preparation of 7-acylamino-3-(sulphomethylthiadiazolylthiomethyl)- or -(sulphomethyltriazolylthiomethyl)-3-cephem-4-carboxylic acids, and their use. CH633557A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/726,378 US4079134A (en) 1976-09-24 1976-09-24 7-Acylamino-3-(5-sulfomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acids
US05/726,377 US4083975A (en) 1976-09-24 1976-09-24 7-Acylamino-3-(3-sulfomethyl-1,2,4-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids

Publications (1)

Publication Number Publication Date
CH633557A5 true CH633557A5 (en) 1982-12-15

Family

ID=27111308

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1166877A CH633557A5 (en) 1976-09-24 1977-09-23 Process for the preparation of 7-acylamino-3-(sulphomethylthiadiazolylthiomethyl)- or -(sulphomethyltriazolylthiomethyl)-3-cephem-4-carboxylic acids, and their use.

Country Status (9)

Country Link
JP (1) JPS5340796A (xx)
CH (1) CH633557A5 (xx)
DE (1) DE2742726A1 (xx)
DK (1) DK417777A (xx)
FR (2) FR2365571A1 (xx)
GB (1) GB1591990A (xx)
IE (1) IE45686B1 (xx)
LU (1) LU78164A1 (xx)
NL (1) NL7710439A (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6140291A (ja) * 1984-07-31 1986-02-26 Shionogi & Co Ltd ヒドロキシアルキルチオセフアロスポリン

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1201621A (en) * 1967-05-18 1970-08-12 Agfa Gevaert Nv Process for stabilizing developed photographic images

Also Published As

Publication number Publication date
DK417777A (da) 1978-03-25
IE45686B1 (en) 1982-10-20
FR2365571B1 (xx) 1983-02-25
NL7710439A (nl) 1978-03-29
GB1591990A (en) 1981-07-01
FR2365571A1 (fr) 1978-04-21
DE2742726A1 (de) 1978-03-30
JPS6156237B2 (xx) 1986-12-01
FR2392014A1 (fr) 1978-12-22
IE45686L (en) 1978-03-24
LU78164A1 (xx) 1978-01-24
JPS5340796A (en) 1978-04-13

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PL Patent ceased