IE45686L - 7-acylamino - 3 - (sulfomethylheterocyclic - thiomethyl)- 3¹- cephem -4- carboxylic acids. - Google Patents
7-acylamino - 3 - (sulfomethylheterocyclic - thiomethyl)- 3¹- cephem -4- carboxylic acids.Info
- Publication number
- IE45686L IE45686L IE771912A IE191277A IE45686L IE 45686 L IE45686 L IE 45686L IE 771912 A IE771912 A IE 771912A IE 191277 A IE191277 A IE 191277A IE 45686 L IE45686 L IE 45686L
- Authority
- IE
- Ireland
- Prior art keywords
- acylamino
- cephem
- carboxylic acids
- sulfomethylheterocyclic
- thiomethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Novel 7-acylamino-3-(sulphomethylthiadiazolylthiomethyl)- or -(sulphomethyltriazolylthiomethyl)-3-cephem-4-carboxylic acids exhibit antibacterial activity against gram-positive and gram-negative bacteria. They are prepared by reacting a corresponding 7-amino- or 7-acylamino-3-acetoxymethyl-cephalosporanic acid with a corresponding sulphomethylthiadiazole-thiol or sulphomethyltriazole-thiol. If a 7-amino-3-acetoxymethyl-cephalosporanic acid is employed, the product is subsequently N-acylated.
[GB1591990A]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/726,378 US4079134A (en) | 1976-09-24 | 1976-09-24 | 7-Acylamino-3-(5-sulfomethyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acids |
US05/726,377 US4083975A (en) | 1976-09-24 | 1976-09-24 | 7-Acylamino-3-(3-sulfomethyl-1,2,4-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
IE45686L true IE45686L (en) | 1978-03-24 |
IE45686B1 IE45686B1 (en) | 1982-10-20 |
Family
ID=27111308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1912/77A IE45686B1 (en) | 1976-09-24 | 1977-09-19 | 7-acylamino-3-(sulfomethylheterocyclicthiomethyl)-3-cephem-4-carboxylic acids |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS5340796A (en) |
CH (1) | CH633557A5 (en) |
DE (1) | DE2742726A1 (en) |
DK (1) | DK417777A (en) |
FR (2) | FR2365571A1 (en) |
GB (1) | GB1591990A (en) |
IE (1) | IE45686B1 (en) |
LU (1) | LU78164A1 (en) |
NL (1) | NL7710439A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6140291A (en) * | 1984-07-31 | 1986-02-26 | Shionogi & Co Ltd | Hydroxyalkylthiocephalosporin |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1201621A (en) * | 1967-05-18 | 1970-08-12 | Agfa Gevaert Nv | Process for stabilizing developed photographic images |
-
1977
- 1977-09-16 FR FR7727983A patent/FR2365571A1/en active Granted
- 1977-09-19 JP JP11391877A patent/JPS5340796A/en active Granted
- 1977-09-19 IE IE1912/77A patent/IE45686B1/en unknown
- 1977-09-20 GB GB39119/77A patent/GB1591990A/en not_active Expired
- 1977-09-21 DK DK417777A patent/DK417777A/en not_active Application Discontinuation
- 1977-09-22 DE DE19772742726 patent/DE2742726A1/en not_active Ceased
- 1977-09-22 LU LU78164A patent/LU78164A1/xx unknown
- 1977-09-23 CH CH1166877A patent/CH633557A5/en not_active IP Right Cessation
- 1977-09-23 NL NL7710439A patent/NL7710439A/en not_active Application Discontinuation
-
1978
- 1978-10-03 FR FR7828261A patent/FR2392014A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
DK417777A (en) | 1978-03-25 |
IE45686B1 (en) | 1982-10-20 |
FR2365571B1 (en) | 1983-02-25 |
NL7710439A (en) | 1978-03-29 |
GB1591990A (en) | 1981-07-01 |
FR2365571A1 (en) | 1978-04-21 |
DE2742726A1 (en) | 1978-03-30 |
JPS6156237B2 (en) | 1986-12-01 |
FR2392014A1 (en) | 1978-12-22 |
CH633557A5 (en) | 1982-12-15 |
LU78164A1 (en) | 1978-01-24 |
JPS5340796A (en) | 1978-04-13 |
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