CH626089A5 - - Google Patents

Download PDF

Info

Publication number
CH626089A5
CH626089A5 CH1502277A CH1502277A CH626089A5 CH 626089 A5 CH626089 A5 CH 626089A5 CH 1502277 A CH1502277 A CH 1502277A CH 1502277 A CH1502277 A CH 1502277A CH 626089 A5 CH626089 A5 CH 626089A5
Authority
CH
Switzerland
Prior art keywords
group
methyl
hydrogen atom
hetero
methoxy
Prior art date
Application number
CH1502277A
Other languages
English (en)
French (fr)
Inventor
William Allen Slusarchyk
Eric Michael Gordon
William Henry Koster
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of CH626089A5 publication Critical patent/CH626089A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1502277A 1976-12-08 1977-12-07 CH626089A5 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/748,426 US4129731A (en) 1976-12-08 1976-12-08 Process for converting 3-methylene cephalosporins to 3-heterothiomethyl cephalosporins

Publications (1)

Publication Number Publication Date
CH626089A5 true CH626089A5 (hu) 1981-10-30

Family

ID=25009398

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1502277A CH626089A5 (hu) 1976-12-08 1977-12-07

Country Status (11)

Country Link
US (1) US4129731A (hu)
JP (1) JPS5373597A (hu)
AU (1) AU511186B2 (hu)
BE (1) BE861639A (hu)
CA (1) CA1087169A (hu)
CH (1) CH626089A5 (hu)
DE (1) DE2754742C2 (hu)
FR (1) FR2373549A1 (hu)
GB (1) GB1591460A (hu)
IE (1) IE46175B1 (hu)
NL (1) NL7712900A (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311837A (en) * 1979-05-01 1982-01-19 Eli Lilly And Company Certain heterocyclic thiomethyl derivatives of 7-(dihalogenated phenylthioacetamido)cephalosporanic acids useful in the treatment of infections caused by _Streptococcus faecalis
NL8005041A (nl) * 1980-09-05 1982-04-01 Gist Brocades Nv Werkwijze voor de bereiding van thioethers, alsmede gesilyleerde thiolen voor toepassing bij deze werkwijze.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275626A (en) * 1962-07-31 1966-09-27 Lilly Co Eli Penicillin conversion via sulfoxide
US3929775A (en) * 1970-12-08 1975-12-30 Takeda Chemical Industries Ltd Process for producing cephalosporin derivatives
CS183696B2 (en) * 1971-02-25 1978-07-31 Robert R Chauvette Method for producing derivatives of 3-methyl-delta up3-cephem-4-carboxylic acid
JPS515396B1 (hu) * 1971-04-05 1976-02-19
US3883518A (en) * 1972-05-15 1975-05-13 Merck & Co Inc 3-Methylene cephalosporins
US3962227A (en) * 1973-02-23 1976-06-08 Eli Lilly And Company 3-halo cephalosporins
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
US3941779A (en) * 1973-11-12 1976-03-02 E. R. Squibb & Sons, Inc. Method for producing 2-(substituted thio)-3-cephem derivatives
US3968109A (en) * 1973-11-23 1976-07-06 E. R. Squibb & Sons, Inc. Production of 2-(thio substituted)cephalosporin sulfoxides and 2-(thio substituted)cephalosporins
US4049806A (en) * 1975-08-15 1977-09-20 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4039534A (en) * 1975-11-17 1977-08-02 E. R. Squibb & Sons, Inc. 4-Thio substituted-Δ2 -cephalosporin intermediates

Also Published As

Publication number Publication date
IE46175L (en) 1978-06-08
US4129731A (en) 1978-12-12
FR2373549B1 (hu) 1980-12-05
JPS5373597A (en) 1978-06-30
AU511186B2 (en) 1980-07-31
GB1591460A (en) 1981-06-24
JPS6118554B2 (hu) 1986-05-13
DE2754742C2 (de) 1986-04-30
DE2754742A1 (de) 1978-06-15
FR2373549A1 (fr) 1978-07-07
IE46175B1 (en) 1983-03-23
AU3038677A (en) 1979-05-17
BE861639A (fr) 1978-06-08
CA1087169A (en) 1980-10-07
NL7712900A (nl) 1978-06-12

Similar Documents

Publication Publication Date Title
CA2146250C (fr) Procede de preparation de derives du taxane
KR20040018538A (ko) Ｕｋ-2ａ의 엑소사이클릭 에스테르 또는 이의 유도체의환원성 분해 및 이로부터 형성된 생성물
CH622264A5 (en) Process for the preparation of new oximes, syn isomers, derived from 7-(aminothiazolylacetamido)cephalosporanic acid
LU86461A1 (fr) Procede de deprotection des esters et ethers allyliques
CH619463A5 (hu)
FR2719046A1 (fr) Procédé de préparation du ginkgolide B à partir du ginkgolide C.
EP0334695A1 (fr) Procédé de préparation de dérivés d'isoquinoléine
CH688319A5 (fr) Procédé pour la préparation du céfixime trihydraté.
CH626089A5 (hu)
CH628900A5 (fr) Procede de preparation de thio-oximes derivees de cephalosporines et de penicillines.
FR2610628A2 (fr) Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
BE1007544A3 (fr) Derives de thioalkylthiocarbacephalosporines.
JP2991348B2 (ja) ７−（ジフェニルメチル）オキシ−９ａ−メトキシマイトサン並びにその製造及び使用
FR2516924A1 (fr) Acides phosphinylalcanoyl- amines a action therapeutique
CH667872A5 (fr) Procede de preparation de 4,4-dialkyl-2-azetidinones.
FR2571056A1 (fr) Derives de cephalosporine et leur procede de preparation
EP0876374B1 (fr) Procede de preparation de la 4'-demethylepipodophyllotoxine a partir de la podophyllotoxine
EP0298177A1 (fr) Nouveau procédé de préparation de dérivés de la pristinamycine IIB
CA1084907A (fr) Derives de la cephalosporine, leur preparation et les compositions qui les contiennent
BE863998A (fr) 1-oxadethiacephames
EP0599732B1 (fr) Dérivés de 1-phénylbicyclo[2.2.2]octane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP0538101A1 (fr) Procédé de préparation de benzo b naphtyridines
EP0853612B1 (fr) Derives d'alfa-hydrazinoacides et procede pour les fabriquer
FR2510999A1 (fr) Nouveaux derives tetrazoliques
EP0161235A2 (fr) Nouveaux dérivés de thiénopyridinone, leur procédé de préparation et compositions pharmaceutiques les contenant

Legal Events

Date Code Title Description
PL Patent ceased