CH624939A5 - - Google Patents

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Publication number
CH624939A5
CH624939A5 CH1161877A CH1161877A CH624939A5 CH 624939 A5 CH624939 A5 CH 624939A5 CH 1161877 A CH1161877 A CH 1161877A CH 1161877 A CH1161877 A CH 1161877A CH 624939 A5 CH624939 A5 CH 624939A5
Authority
CH
Switzerland
Prior art keywords
lower alkyl
methoxy
trimethyl
group
octahydro
Prior art date
Application number
CH1161877A
Other languages
English (en)
French (fr)
Inventor
Thomas Richard Lewis
William Francis Michne
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Priority claimed from DE19782811849 external-priority patent/DE2811849A1/de
Publication of CH624939A5 publication Critical patent/CH624939A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH1161877A 1976-09-22 1977-09-22 CH624939A5 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72537176A 1976-09-22 1976-09-22
US78574677A 1977-04-08 1977-04-08
US05/818,713 US4119628A (en) 1976-09-22 1977-07-25 Process for preparing hexahydro-11 (eq)-CH2 CH2 COR5 -2,6-methano-3-benzazocines
DE19782811849 DE2811849A1 (de) 1976-09-22 1978-03-17 2,6-methano-3-benzazocine, verfahren zu deren herstellung und arzneimittel

Publications (1)

Publication Number Publication Date
CH624939A5 true CH624939A5 (de) 1981-08-31

Family

ID=27432292

Family Applications (2)

Application Number Title Priority Date Filing Date
CH81881A CH626882A5 (de) 1976-09-22 1977-09-22
CH1161877A CH624939A5 (de) 1976-09-22 1977-09-22

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH81881A CH626882A5 (de) 1976-09-22 1977-09-22

Country Status (10)

Country Link
US (2) US4119628A (de)
JP (1) JPS5340777A (de)
BE (1) BE858866A (de)
CA (1) CA1095905A (de)
CH (2) CH626882A5 (de)
DE (1) DE2742715A1 (de)
FR (2) FR2375216A1 (de)
GB (1) GB1551562A (de)
LU (1) LU78162A1 (de)
NL (1) NL187630C (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255579A (en) * 1974-05-20 1981-03-10 Sterling Drug Inc. 11-Substituted hexahydro-2,6-methano-3-benzazocines
BE864950A (fr) * 1976-09-22 1978-09-18 Sterling Drug Inc 2,6-methano-3-benzazocines
EP0019056A1 (de) * 1979-03-26 1980-11-26 Sterling Drug Inc. Verfahren zur Herstellung von 11-niedrig-Alkoxy- und niedrig-Alkylthio-3-oxo-niedrig-alkyl-hexahydro-2,6-methano-3-benzazocinen
US4912114A (en) * 1988-03-18 1990-03-27 Sandoz Ltd. Morphinan derivatives
WO2014072809A2 (en) * 2012-11-09 2014-05-15 Purdue Pharma L.P. Benzomorphan analogs and the use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones

Also Published As

Publication number Publication date
NL187630B (nl) 1991-07-01
US4148794A (en) 1979-04-10
FR2378768B1 (de) 1981-05-29
BE858866A (fr) 1978-03-20
AU2903077A (en) 1979-03-29
NL187630C (nl) 1991-12-02
DE2742715A1 (de) 1978-03-23
CH626882A5 (de) 1981-12-15
LU78162A1 (de) 1978-06-01
FR2375216A1 (fr) 1978-07-21
US4119628A (en) 1978-10-10
CA1095905A (en) 1981-02-17
NL7710325A (nl) 1978-03-28
GB1551562A (en) 1979-08-30
JPS5340777A (en) 1978-04-13
FR2378768A1 (fr) 1978-08-25
FR2375216B1 (de) 1980-09-19
JPS6224424B2 (de) 1987-05-28

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Legal Events

Date Code Title Description
PL Patent ceased