CH614939A5 - Process for the preparation of substituted heterocyclic N-alkanolamines - Google Patents
Process for the preparation of substituted heterocyclic N-alkanolaminesInfo
- Publication number
- CH614939A5 CH614939A5 CH730176A CH730176A CH614939A5 CH 614939 A5 CH614939 A5 CH 614939A5 CH 730176 A CH730176 A CH 730176A CH 730176 A CH730176 A CH 730176A CH 614939 A5 CH614939 A5 CH 614939A5
- Authority
- CH
- Switzerland
- Prior art keywords
- compounds
- formula
- alkanolamines
- preparation
- substituted heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Compounds of formula IV which have good pharmacological properties are prepared by reaction of a lower alkyl sulphate, an alkali metal alkoxide and a lower nitroalkane with a compound of formula I <IMAGE> and subsequent reduction of the intermediate compound. By an oxidation of the compounds of formula IV, N-oxide compounds are obtained. The compounds obtained are intermediates in the synthesis of heterocyclic benzamides, such as those which are described in Swiss Patent No. 596,175, used as antiemetic agents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7518175A FR2314177A1 (en) | 1975-06-09 | 1975-06-09 | NEW N-ALKANOL SUBSTITUTED HETEROCYCLIC AMINES, THEIR DERIVATIVES, THEIR METHODS OF PREPARATION |
Publications (1)
Publication Number | Publication Date |
---|---|
CH614939A5 true CH614939A5 (en) | 1979-12-28 |
Family
ID=9156325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH730176A CH614939A5 (en) | 1975-06-09 | 1976-06-09 | Process for the preparation of substituted heterocyclic N-alkanolamines |
Country Status (35)
Country | Link |
---|---|
JP (2) | JPS51149268A (en) |
AR (1) | AR211927A1 (en) |
AT (1) | AT349456B (en) |
AU (1) | AU504920B2 (en) |
BE (1) | BE842058A (en) |
BG (1) | BG24800A3 (en) |
CA (1) | CA1077949A (en) |
CH (1) | CH614939A5 (en) |
CS (1) | CS188284B2 (en) |
DD (1) | DD125072A5 (en) |
DE (1) | DE2623000A1 (en) |
DK (1) | DK251876A (en) |
EG (1) | EG13867A (en) |
ES (1) | ES448642A1 (en) |
FI (1) | FI761641A (en) |
FR (1) | FR2314177A1 (en) |
GB (2) | GB1499708A (en) |
HK (1) | HK63679A (en) |
HU (1) | HU171835B (en) |
IE (1) | IE43228B1 (en) |
IL (1) | IL49595A (en) |
IN (1) | IN141747B (en) |
LU (1) | LU75097A1 (en) |
MC (1) | MC1104A1 (en) |
MW (1) | MW1576A1 (en) |
NL (1) | NL188526C (en) |
NO (1) | NO761886L (en) |
OA (1) | OA05344A (en) |
PH (1) | PH15172A (en) |
PT (1) | PT65163B (en) |
RO (1) | RO69253A (en) |
SE (1) | SE410852B (en) |
YU (1) | YU39966B (en) |
ZA (1) | ZA763041B (en) |
ZM (1) | ZM6476A1 (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2684965A (en) * | 1950-08-10 | 1954-07-27 | Abbott Lab | Aminoalkylpiperidines |
-
1975
- 1975-06-09 FR FR7518175A patent/FR2314177A1/en active Granted
-
1976
- 1976-05-17 IL IL49595A patent/IL49595A/en unknown
- 1976-05-20 MC MC761197A patent/MC1104A1/en unknown
- 1976-05-21 BE BE1007403A patent/BE842058A/en not_active IP Right Cessation
- 1976-05-21 ZA ZA763041A patent/ZA763041B/en unknown
- 1976-05-22 DE DE19762623000 patent/DE2623000A1/en not_active Withdrawn
- 1976-05-24 AR AR263373A patent/AR211927A1/en active
- 1976-05-25 AU AU14259/76A patent/AU504920B2/en not_active Expired
- 1976-05-27 IN IN925/CAL/76A patent/IN141747B/en unknown
- 1976-05-28 YU YU1310/76A patent/YU39966B/en unknown
- 1976-06-01 AT AT399876A patent/AT349456B/en not_active IP Right Cessation
- 1976-06-01 IE IE1165/76A patent/IE43228B1/en unknown
- 1976-06-01 PT PT65163A patent/PT65163B/en unknown
- 1976-06-02 RO RO7686326A patent/RO69253A/en unknown
- 1976-06-03 ZM ZM64/76A patent/ZM6476A1/en unknown
- 1976-06-03 NO NO761886A patent/NO761886L/no unknown
- 1976-06-04 BG BG7600033361A patent/BG24800A3/en unknown
- 1976-06-04 CS CS763723A patent/CS188284B2/en unknown
- 1976-06-04 LU LU75097A patent/LU75097A1/xx unknown
- 1976-06-05 OA OA55841A patent/OA05344A/en unknown
- 1976-06-07 ES ES448642A patent/ES448642A1/en not_active Expired
- 1976-06-08 GB GB18917/77A patent/GB1499708A/en not_active Expired
- 1976-06-08 SE SE7606425A patent/SE410852B/en not_active IP Right Cessation
- 1976-06-08 GB GB23694/76A patent/GB1499707A/en not_active Expired
- 1976-06-08 DK DK251876A patent/DK251876A/en unknown
- 1976-06-09 HU HU76SO00001170A patent/HU171835B/en unknown
- 1976-06-09 NL NLAANVRAGE7606241,A patent/NL188526C/en not_active IP Right Cessation
- 1976-06-09 FI FI761641A patent/FI761641A/fi not_active Application Discontinuation
- 1976-06-09 CA CA254,481A patent/CA1077949A/en not_active Expired
- 1976-06-09 JP JP51068166A patent/JPS51149268A/en active Granted
- 1976-06-09 JP JP51068167A patent/JPS6059227B2/en not_active Expired
- 1976-06-09 CH CH730176A patent/CH614939A5/en not_active IP Right Cessation
- 1976-06-09 MW MW15/76A patent/MW1576A1/en unknown
- 1976-06-09 DD DD193271A patent/DD125072A5/xx not_active IP Right Cessation
- 1976-06-20 EG EG325/76A patent/EG13867A/en active
-
1979
- 1979-09-06 HK HK636/79A patent/HK63679A/en unknown
-
1980
- 1980-04-25 PH PH23958A patent/PH15172A/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |