CH612424A5 - - Google Patents
Info
- Publication number
- CH612424A5 CH612424A5 CH216478A CH216478A CH612424A5 CH 612424 A5 CH612424 A5 CH 612424A5 CH 216478 A CH216478 A CH 216478A CH 216478 A CH216478 A CH 216478A CH 612424 A5 CH612424 A5 CH 612424A5
- Authority
- CH
- Switzerland
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1683674A GB1477664A (en) | 1974-04-17 | 1974-04-17 | Pyridine derivatives |
| YU1507/81A YU42409B (en) | 1974-04-17 | 1981-06-15 | Process for obtaining new pyridine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH612424A5 true CH612424A5 (es) | 1979-07-31 |
Family
ID=26252269
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH216478A CH612424A5 (es) | 1974-04-17 | 1975-04-16 | |
| CH485775A CH609045A5 (es) | 1974-04-17 | 1975-04-16 | |
| CH216378A CH610890A5 (es) | 1974-04-17 | 1975-04-16 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH485775A CH609045A5 (es) | 1974-04-17 | 1975-04-16 | |
| CH216378A CH610890A5 (es) | 1974-04-17 | 1975-04-16 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4018929A (es) |
| JP (1) | JPS5951536B2 (es) |
| AR (4) | AR211097A1 (es) |
| AT (1) | AT344170B (es) |
| BE (1) | BE827844A (es) |
| CA (1) | CA1070313A (es) |
| CH (3) | CH612424A5 (es) |
| DD (2) | DD126887A5 (es) |
| DE (1) | DE2516025A1 (es) |
| ES (4) | ES436581A1 (es) |
| FR (1) | FR2267775B1 (es) |
| GB (1) | GB1477664A (es) |
| HU (1) | HU171420B (es) |
| IL (1) | IL47084A (es) |
| LU (2) | LU72284A1 (es) |
| NL (2) | NL183580C (es) |
| SE (2) | SE424320B (es) |
| YU (1) | YU42409B (es) |
| ZA (1) | ZA752243B (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1593609A (en) * | 1978-01-31 | 1981-07-22 | Christiaens Sa A | Pyridine sulfonamides |
| US4776878A (en) * | 1978-12-04 | 1988-10-11 | E. I. Du Pont De Nemours And Company | Agricultural pyridinesulfonamides |
| LU85193A1 (fr) * | 1984-01-31 | 1985-09-12 | Christiaens Sa A | Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation |
| DE3529529A1 (de) * | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | Verfahren zur herstellung einer stabilen modifikation von torasemid |
| US4853389A (en) * | 1987-07-24 | 1989-08-01 | American Home Products Corporation | Diuretic and antihypertensive substituted-5-pyrimidinesulfonylureas |
| US4914203A (en) * | 1987-07-24 | 1990-04-03 | American Home Products Corporation | 5 step process for preparing certain 2,4-diamino-5-pyrimidine-sulfonyl ureas |
| US5166162A (en) * | 1990-03-02 | 1992-11-24 | Adir Et Compagnie | Pyridylsulfonylurea and pyridylsulfonylthiourea compounds |
| FR2659080B1 (fr) * | 1990-03-02 | 1994-07-08 | Adir | Nouveaux derives de la pyridylsulfonyluree et de la pyridylsulfonylthiouree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| US5486530A (en) * | 1991-04-27 | 1996-01-23 | Boehringer Mannheim Gmbh | Use of torasemide for the treatment of brain oedemas |
| IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
| HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
| US6166045A (en) * | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
| US8008283B2 (en) * | 1998-12-23 | 2011-08-30 | Neurotherapeutics Pharma, Inc. | Methods and compositions for the treatment of neuropsychiatric disorders |
| US7214711B2 (en) * | 1998-12-23 | 2007-05-08 | Neurotherapeutics Pharma Llc | Method of treating migraine headache without aura |
| US8722668B2 (en) * | 1998-12-23 | 2014-05-13 | Daryl W. Hochman | Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders |
| MXPA02001369A (es) | 1999-08-11 | 2005-08-26 | Teva Pharma | Torasemidas polimorfas. |
| IL157539A0 (en) * | 2000-02-17 | 2004-03-28 | Teva Pharma | A stable pharmaceutical formulation comprising torsemide modification ii |
| EP1741429A3 (en) * | 2000-03-20 | 2007-01-17 | Teva Pharmaceutical Industries Ltd. | Processes for preparing torsemide |
| SK14802002A3 (sk) | 2000-03-20 | 2003-05-02 | Teva Pharmaceutical Industries Ltd. | Nový spôsob prípravy medziproduktu torsemidu |
| HRP20000162B1 (en) | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
| HRP20000328A2 (en) | 2000-05-19 | 2002-02-28 | Pliva Farmaceutska Ind Dionik | Novel polymorph v of torasemide |
| US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
| IN192178B (es) | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
| IL149771A0 (en) * | 2002-05-21 | 2002-11-10 | Fintech Lab Ltd | Process for preparation of torsemide |
| HRP20020603B1 (en) * | 2002-07-19 | 2008-11-30 | Pliva D.D. | New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide |
| ES2362998T3 (es) | 2002-08-19 | 2011-07-18 | Pfizer Inc. | Terapia de combinación para enfermedades hiperproliferativas. |
| CA2401546C (en) * | 2002-09-06 | 2006-09-19 | Brantford Chemicals Inc. | Preparation of derivatives of 3-sulfonamido-4-phenylaminopyridine |
| ITMI20022749A1 (it) * | 2002-12-23 | 2004-06-24 | Cosma S P A | Nuovo procedimento per la sintesi della tosemide, in particolare della forma ii pura e stabile. |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| US20050215600A1 (en) * | 2003-10-27 | 2005-09-29 | Arie Gutman | Polymorphs of torsemide hydrochloride and process for production thereof |
| US7378527B2 (en) * | 2004-03-16 | 2008-05-27 | Daqing Che | Process for the preparation of torsemide and related intermediates |
| US20070149526A1 (en) * | 2005-10-17 | 2007-06-28 | Neurotherapeutics Pharma, L.L.C. | Diuretic and diuretic-like compound analogs |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US7625896B2 (en) * | 2005-11-25 | 2009-12-01 | Hoffman-La Roche Inc. | Pyridylsulfonamide derivatives |
| US7939532B2 (en) * | 2006-10-26 | 2011-05-10 | Hoffmann-La Roche Inc. | Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents |
| US8404896B2 (en) | 2006-12-01 | 2013-03-26 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
| US7879884B2 (en) * | 2007-05-16 | 2011-02-01 | Hoffmann-La Roche Inc. | Aryl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents |
| NL2006622C2 (en) | 2011-04-18 | 2012-10-22 | Eurovet Animal Health B V | Use of a composition comprising torasemide. |
| EP2887806B1 (en) | 2012-07-20 | 2019-11-13 | University Of Rochester | Method of treating and preventing brain impairment using na+-k+ -2ci- cotransporter isoform 1 inhibitors |
| AU2014255381A1 (en) | 2013-04-17 | 2015-10-08 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| EP3888749A1 (en) * | 2015-02-16 | 2021-10-06 | The University of Queensland | Sulfonylureas and related compounds and use of same |
| PL3661925T3 (pl) | 2017-07-07 | 2022-02-28 | Inflazome Limited | Nowe związki sulfonamidowo karboksyamidowe |
| MX2021008533A (es) | 2019-01-18 | 2021-08-19 | Astrazeneca Ab | Inhibidores de la pcsk9 y metodos de uso de los mismos. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3674794A (en) * | 1970-03-18 | 1972-07-04 | Ciba Geigy Corp | Certain-3-pyridine-sulfonamide derivatives |
| GB1368948A (en) * | 1970-11-11 | 1974-10-02 | Manuf Prod Pharma | Pyridine derivatives |
| US3904636A (en) * | 1971-11-09 | 1975-09-09 | Christiaens Sa A | 3-sulfonamido-4-phenyl aminopyridines and derivatives |
| GB1414793A (en) * | 1972-07-28 | 1975-11-19 | Manuf Prod Pharma | Derivatives of phenylaminopyridine |
-
1974
- 1974-04-17 GB GB1683674A patent/GB1477664A/en not_active Expired
-
1975
- 1975-04-08 ZA ZA00752243A patent/ZA752243B/xx unknown
- 1975-04-11 BE BE155330A patent/BE827844A/xx not_active IP Right Cessation
- 1975-04-12 DE DE19752516025 patent/DE2516025A1/de active Granted
- 1975-04-14 HU HU75CI00001569A patent/HU171420B/hu unknown
- 1975-04-14 ES ES436581A patent/ES436581A1/es not_active Expired
- 1975-04-14 IL IL47084A patent/IL47084A/xx unknown
- 1975-04-15 LU LU72284A patent/LU72284A1/xx unknown
- 1975-04-16 CH CH216478A patent/CH612424A5/xx not_active IP Right Cessation
- 1975-04-16 NL NLAANVRAGE7504521,A patent/NL183580C/xx active Protection Beyond IP Right Term
- 1975-04-16 SE SE7504409A patent/SE424320B/xx unknown
- 1975-04-16 CH CH485775A patent/CH609045A5/xx active Protection Beyond IP Right Term
- 1975-04-16 CA CA224,805A patent/CA1070313A/en not_active Expired
- 1975-04-16 CH CH216378A patent/CH610890A5/xx active Protection Beyond IP Right Term
- 1975-04-16 AT AT288275A patent/AT344170B/de not_active IP Right Cessation
- 1975-04-16 FR FR7511791A patent/FR2267775B1/fr not_active Expired
- 1975-04-16 US US05/568,759 patent/US4018929A/en not_active Expired - Lifetime
- 1975-04-17 JP JP50047371A patent/JPS5951536B2/ja not_active Expired
- 1975-04-17 DD DD194800A patent/DD126887A5/xx unknown
- 1975-04-17 AR AR258409A patent/AR211097A1/es active
- 1975-04-17 DD DD185508A patent/DD121936A5/xx unknown
-
1976
- 1976-03-19 AR AR262626A patent/AR208769A1/es active
- 1976-03-19 AR AR262625A patent/AR208768A1/es active
- 1976-03-19 AR AR262627A patent/AR208770A1/es active
- 1976-11-15 ES ES453327A patent/ES453327A1/es not_active Expired
- 1976-11-15 ES ES453328A patent/ES453328A1/es not_active Expired
- 1976-11-15 ES ES453329A patent/ES453329A1/es not_active Expired
-
1979
- 1979-09-13 SE SE7907618A patent/SE7907618L/sv not_active Application Discontinuation
-
1980
- 1980-02-07 US US06/119,601 patent/USRE30633E/en not_active Expired - Lifetime
-
1981
- 1981-06-15 YU YU1507/81A patent/YU42409B/xx unknown
-
1993
- 1993-06-30 LU LU88346C patent/LU88346I2/fr unknown
-
1994
- 1994-07-27 NL NL940014C patent/NL940014I2/nl unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |