CH610877A5 - Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acid - Google Patents

Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acid

Info

Publication number
CH610877A5
CH610877A5 CH379076A CH379076A CH610877A5 CH 610877 A5 CH610877 A5 CH 610877A5 CH 379076 A CH379076 A CH 379076A CH 379076 A CH379076 A CH 379076A CH 610877 A5 CH610877 A5 CH 610877A5
Authority
CH
Switzerland
Prior art keywords
acid
dichloroanilino
compound
preparation
addition salts
Prior art date
Application number
CH379076A
Inventor
Fujio Nohara
Original Assignee
Ikeda Mohando Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ikeda Mohando Co filed Critical Ikeda Mohando Co
Publication of CH610877A5 publication Critical patent/CH610877A5/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/12Formation of amino and carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Substituted phenyl N-(2,6-dichlorophenyl)benzymidate, obtained by condensation of a salt of 2,6-dichlorophenol with the imidoyl chloride, is converted by the Chapman rearrangement to the compound of formula <IMAGE> in which Q is a radical chosen from the cyano and alkoxycarbonyl groups and Z is a substituted or unsubstituted phenyl group. By hydrolysis of the compound (III), o-(2,6-dichloroanilino)phenylacetic acid is obtained. This compound is useful as an analgesic and non-steroidal anti-inflammatory agent.
CH379076A 1975-03-31 1976-03-26 Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acid CH610877A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50038682A JPS51113842A (en) 1975-03-31 1975-03-31 Process for preparing o-(2,6-dichloroanilino)phenyl acetic acid

Publications (1)

Publication Number Publication Date
CH610877A5 true CH610877A5 (en) 1979-05-15

Family

ID=12532044

Family Applications (1)

Application Number Title Priority Date Filing Date
CH379076A CH610877A5 (en) 1975-03-31 1976-03-26 Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acid

Country Status (13)

Country Link
JP (1) JPS51113842A (en)
AU (1) AU504223B2 (en)
CA (1) CA1050565A (en)
CH (1) CH610877A5 (en)
DE (1) DE2613838A1 (en)
DK (1) DK157576A (en)
FI (1) FI760842A (en)
FR (1) FR2306196A1 (en)
GB (1) GB1532087A (en)
GR (1) GR59322B (en)
NL (1) NL7603348A (en)
NO (1) NO144667C (en)
SE (1) SE413314B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5815940A (en) 1981-07-23 1983-01-29 Eisai Co Ltd Polyprenyl compound, its preparation and drug containing the same
ES2065928T3 (en) * 1989-01-27 1995-03-01 Heumann Pharma Gmbh & Co PROCEDURE FOR THE MANUFACTURE OF 2,6-DICHLORODIFENYLAMINACETIC ACID DERIVATIVES.
CN108947861A (en) * 2018-08-17 2018-12-07 复旦大学 The synthetic method of C14H10Cl2NNaO2

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053269A (en) * 1964-11-27

Also Published As

Publication number Publication date
JPS51113842A (en) 1976-10-07
FR2306196B1 (en) 1979-06-29
NL7603348A (en) 1976-10-04
SE413314B (en) 1980-05-19
SE7603779L (en) 1976-10-01
NO761097L (en) 1976-10-01
FI760842A (en) 1976-10-01
JPS565218B2 (en) 1981-02-04
AU1237076A (en) 1977-09-29
GR59322B (en) 1977-12-13
GB1532087A (en) 1978-11-15
DK157576A (en) 1976-10-01
NO144667C (en) 1981-10-14
AU504223B2 (en) 1979-10-04
NO144667B (en) 1981-07-06
CA1050565A (en) 1979-03-13
DE2613838A1 (en) 1976-10-07
FR2306196A1 (en) 1976-10-29

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Legal Events

Date Code Title Description
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