CH608022A5 - Process for the preparation of halogenated aminoglycoside antibiotics and the use thereof - Google Patents

Process for the preparation of halogenated aminoglycoside antibiotics and the use thereof

Info

Publication number
CH608022A5
CH608022A5 CH1823673A CH1823673A CH608022A5 CH 608022 A5 CH608022 A5 CH 608022A5 CH 1823673 A CH1823673 A CH 1823673A CH 1823673 A CH1823673 A CH 1823673A CH 608022 A5 CH608022 A5 CH 608022A5
Authority
CH
Switzerland
Prior art keywords
halogenated
preparation
aminoglycoside antibiotics
antibiotics
deoxyaminoglycoside
Prior art date
Application number
CH1823673A
Other languages
English (en)
Inventor
Kentaro Hiraga
Tetsuya Okutani
Kouichi Yoshioka
Tsunehiko Asako
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP216673A external-priority patent/JPS5652917B2/ja
Priority claimed from JP732167A external-priority patent/JPS5238557B2/ja
Priority claimed from JP5828373A external-priority patent/JPS505304A/ja
Priority claimed from JP5828273A external-priority patent/JPS505303A/ja
Priority claimed from JP48077261A external-priority patent/JPS5025548A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CH608022A5 publication Critical patent/CH608022A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
CH1823673A 1972-12-29 1973-12-28 Process for the preparation of halogenated aminoglycoside antibiotics and the use thereof CH608022A5 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP216673A JPS5652917B2 (xx) 1972-12-29 1972-12-29
JP732167A JPS5238557B2 (xx) 1972-12-29 1972-12-29
JP5828373A JPS505304A (xx) 1973-05-24 1973-05-24
JP5828273A JPS505303A (xx) 1973-05-24 1973-05-24
JP48077261A JPS5025548A (xx) 1973-07-09 1973-07-09

Publications (1)

Publication Number Publication Date
CH608022A5 true CH608022A5 (en) 1978-12-15

Family

ID=27518209

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1823673A CH608022A5 (en) 1972-12-29 1973-12-28 Process for the preparation of halogenated aminoglycoside antibiotics and the use thereof

Country Status (11)

Country Link
US (1) US4029883A (xx)
AT (1) AT332544B (xx)
CA (1) CA1021327A (xx)
CH (1) CH608022A5 (xx)
DE (1) DE2364999A1 (xx)
FR (1) FR2223357B1 (xx)
GB (1) GB1460039A (xx)
NL (1) NL7317827A (xx)
NO (1) NO139522C (xx)
SE (1) SE402777C (xx)
SU (1) SU873888A3 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH630644A5 (de) * 1974-04-10 1982-06-30 Takeda Chemical Industries Ltd Verfahren zur herstellung von desoxyaminoglykosid-antibiotika.
US3960833A (en) * 1974-11-29 1976-06-01 Bristol-Myers Company Butirosin A 3",5"-O-isopropylidene derivatives
PT66654B (en) * 1976-06-10 1978-11-10 Canas Rodriguez Antonio Process for the preparation of synthetic aminoglicosides
US4347354A (en) * 1977-04-28 1982-08-31 Bristol-Myers Company Preparation of 1-N-[ω-amino-α-hydroxyalkanoyl]aminoglycoside polysilylated antibiotics and products obtained therefrom
US4424343A (en) 1977-04-28 1984-01-03 Bristol Myers Company Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products
US4284764A (en) * 1978-04-04 1981-08-18 Schering Corporation Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy derivatives produced thereby
DE2840907A1 (de) * 1978-09-20 1980-04-03 Bayer Ag Selektiv geschuetzte 4,6-di-o-(aminoglykosyl)-1,3-diaminocyclitole
ZA803031B (en) * 1979-06-07 1981-05-27 Erba Farmitalia Paromomycin derivatives
JPS5643297A (en) * 1979-09-19 1981-04-21 Microbial Chem Res Found 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation
US4645760A (en) * 1982-07-30 1987-02-24 Health Research Inc. Activated aminoglycosides and aminoglycoside-aminocyclitols pharmaceutical compositions and method of use
US4661474A (en) * 1984-12-15 1987-04-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 2',3'-dideoxy-2'-fluorokanamycin A and 1-N-(α-hydroxy-ω-aminoalkanoyl) derivatives thereof
US5900406A (en) * 1991-07-09 1999-05-04 Nzym, Inc. Use of antibiotics of the type 2-deoxystreptamine substituted with aminosugars to inhibit growth of microorganisms containing group I introns

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3721664A (en) * 1970-01-27 1973-03-20 Hoffmann La Roche Preparation of 5-cytosine nucleosides
JPS507595B1 (xx) * 1970-07-29 1975-03-27

Also Published As

Publication number Publication date
US4029883A (en) 1977-06-14
NL7317827A (xx) 1974-07-02
FR2223357A1 (xx) 1974-10-25
ATA1072973A (de) 1976-01-15
CA1021327A (en) 1977-11-22
GB1460039A (en) 1976-12-31
SE402777C (sv) 1979-01-25
SU873888A3 (ru) 1981-10-15
NO139522C (no) 1979-03-28
DE2364999A1 (de) 1974-07-11
SE402777B (sv) 1978-07-17
AU6403773A (en) 1975-07-03
FR2223357B1 (xx) 1976-04-30
AT332544B (de) 1976-10-11
NO139522B (no) 1978-12-18

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Legal Events

Date Code Title Description
PL Patent ceased