AT332544B - Verfahren zur dehydroxylierung von aminoglykosid-antibiotika - Google Patents

Verfahren zur dehydroxylierung von aminoglykosid-antibiotika

Info

Publication number
AT332544B
AT332544B AT1072973A AT1072973A AT332544B AT 332544 B AT332544 B AT 332544B AT 1072973 A AT1072973 A AT 1072973A AT 1072973 A AT1072973 A AT 1072973A AT 332544 B AT332544 B AT 332544B
Authority
AT
Austria
Prior art keywords
dehydroxylation
aminoglycoside antibiotics
aminoglycoside
antibiotics
Prior art date
Application number
AT1072973A
Other languages
English (en)
Other versions
ATA1072973A (de
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP216673A external-priority patent/JPS5652917B2/ja
Priority claimed from JP732167A external-priority patent/JPS5238557B2/ja
Priority claimed from JP5828373A external-priority patent/JPS505304A/ja
Priority claimed from JP5828273A external-priority patent/JPS505303A/ja
Priority claimed from JP48077261A external-priority patent/JPS5025548A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ATA1072973A publication Critical patent/ATA1072973A/de
Application granted granted Critical
Publication of AT332544B publication Critical patent/AT332544B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
AT1072973A 1972-12-29 1973-12-21 Verfahren zur dehydroxylierung von aminoglykosid-antibiotika AT332544B (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP216673A JPS5652917B2 (de) 1972-12-29 1972-12-29
JP732167A JPS5238557B2 (de) 1972-12-29 1972-12-29
JP5828373A JPS505304A (de) 1973-05-24 1973-05-24
JP5828273A JPS505303A (de) 1973-05-24 1973-05-24
JP48077261A JPS5025548A (de) 1973-07-09 1973-07-09

Publications (2)

Publication Number Publication Date
ATA1072973A ATA1072973A (de) 1976-01-15
AT332544B true AT332544B (de) 1976-10-11

Family

ID=27518209

Family Applications (1)

Application Number Title Priority Date Filing Date
AT1072973A AT332544B (de) 1972-12-29 1973-12-21 Verfahren zur dehydroxylierung von aminoglykosid-antibiotika

Country Status (11)

Country Link
US (1) US4029883A (de)
AT (1) AT332544B (de)
CA (1) CA1021327A (de)
CH (1) CH608022A5 (de)
DE (1) DE2364999A1 (de)
FR (1) FR2223357B1 (de)
GB (1) GB1460039A (de)
NL (1) NL7317827A (de)
NO (1) NO139522C (de)
SE (1) SE402777C (de)
SU (1) SU873888A3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH630644A5 (de) * 1974-04-10 1982-06-30 Takeda Chemical Industries Ltd Verfahren zur herstellung von desoxyaminoglykosid-antibiotika.
US3960833A (en) * 1974-11-29 1976-06-01 Bristol-Myers Company Butirosin A 3",5"-O-isopropylidene derivatives
PT66654B (en) * 1976-06-10 1978-11-10 Canas Rodriguez Antonio Process for the preparation of synthetic aminoglicosides
US4347354A (en) * 1977-04-28 1982-08-31 Bristol-Myers Company Preparation of 1-N-[ω-amino-α-hydroxyalkanoyl]aminoglycoside polysilylated antibiotics and products obtained therefrom
US4424343A (en) 1977-04-28 1984-01-03 Bristol Myers Company Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products
US4284764A (en) * 1978-04-04 1981-08-18 Schering Corporation Process for the preparation of 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and novel 5-fluoro-5-deoxy and 5-epi-fluoro-5-deoxy derivatives produced thereby
DE2840907A1 (de) * 1978-09-20 1980-04-03 Bayer Ag Selektiv geschuetzte 4,6-di-o-(aminoglykosyl)-1,3-diaminocyclitole
ZA803031B (en) * 1979-06-07 1981-05-27 Erba Farmitalia Paromomycin derivatives
JPS5643297A (en) * 1979-09-19 1981-04-21 Microbial Chem Res Found 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation
US4645760A (en) * 1982-07-30 1987-02-24 Health Research Inc. Activated aminoglycosides and aminoglycoside-aminocyclitols pharmaceutical compositions and method of use
US4661474A (en) * 1984-12-15 1987-04-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 2',3'-dideoxy-2'-fluorokanamycin A and 1-N-(α-hydroxy-ω-aminoalkanoyl) derivatives thereof
US5900406A (en) * 1991-07-09 1999-05-04 Nzym, Inc. Use of antibiotics of the type 2-deoxystreptamine substituted with aminosugars to inhibit growth of microorganisms containing group I introns

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3721664A (en) * 1970-01-27 1973-03-20 Hoffmann La Roche Preparation of 5-cytosine nucleosides
JPS507595B1 (de) * 1970-07-29 1975-03-27

Also Published As

Publication number Publication date
US4029883A (en) 1977-06-14
NL7317827A (de) 1974-07-02
FR2223357A1 (de) 1974-10-25
ATA1072973A (de) 1976-01-15
CA1021327A (en) 1977-11-22
GB1460039A (en) 1976-12-31
SE402777C (sv) 1979-01-25
SU873888A3 (ru) 1981-10-15
CH608022A5 (en) 1978-12-15
NO139522C (no) 1979-03-28
DE2364999A1 (de) 1974-07-11
SE402777B (sv) 1978-07-17
AU6403773A (en) 1975-07-03
FR2223357B1 (de) 1976-04-30
NO139522B (no) 1978-12-18

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee