GB1523634A - Aminoglycoside antibiotics and a process for their production - Google Patents

Aminoglycoside antibiotics and a process for their production

Info

Publication number
GB1523634A
GB1523634A GB46249/75A GB4624975A GB1523634A GB 1523634 A GB1523634 A GB 1523634A GB 46249/75 A GB46249/75 A GB 46249/75A GB 4624975 A GB4624975 A GB 4624975A GB 1523634 A GB1523634 A GB 1523634A
Authority
GB
United Kingdom
Prior art keywords
production
aminoglycoside antibiotics
kanamycin
deoxytobramycin
deoxykanamycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB46249/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB1523634A publication Critical patent/GB1523634A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

6''-Deoxykanamycin B and 6''-deoxytobramycin are prepared in a 5-stage process from kanamycin B by dehydroxylation in position 6'' and 3', 6'' respectively. These semisynthetic derivatives of kanamycin B are valuable antibacterial agents.
GB46249/75A 1974-11-13 1975-11-07 Aminoglycoside antibiotics and a process for their production Expired GB1523634A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52329274A 1974-11-13 1974-11-13

Publications (1)

Publication Number Publication Date
GB1523634A true GB1523634A (en) 1978-09-06

Family

ID=24084408

Family Applications (1)

Application Number Title Priority Date Filing Date
GB46249/75A Expired GB1523634A (en) 1974-11-13 1975-11-07 Aminoglycoside antibiotics and a process for their production

Country Status (14)

Country Link
JP (1) JPS5170751A (en)
BE (1) BE835328A (en)
CA (1) CA1053666A (en)
CH (1) CH621797A5 (en)
DE (1) DE2550429A1 (en)
DK (1) DK508075A (en)
FR (1) FR2290910A1 (en)
GB (1) GB1523634A (en)
IE (1) IE42175B1 (en)
LU (1) LU73790A1 (en)
NL (1) NL165754C (en)
SE (1) SE7512598L (en)
YU (1) YU287675A (en)
ZA (1) ZA757044B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5643297A (en) * 1979-09-19 1981-04-21 Microbial Chem Res Found 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation

Also Published As

Publication number Publication date
NL7513133A (en) 1976-05-17
DK508075A (en) 1976-05-14
CH621797A5 (en) 1981-02-27
BE835328A (en) 1976-05-06
IE42175B1 (en) 1980-06-18
AU8620375A (en) 1977-05-05
NL165754C (en) 1981-05-15
NL165754B (en) 1980-12-15
DE2550429A1 (en) 1976-05-20
JPS5170751A (en) 1976-06-18
SE7512598L (en) 1976-05-14
IE42175L (en) 1976-05-13
YU287675A (en) 1982-05-31
LU73790A1 (en) 1976-09-06
FR2290910A1 (en) 1976-06-11
ZA757044B (en) 1977-01-26
CA1053666A (en) 1979-05-01
FR2290910B1 (en) 1978-07-28

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee