CH606023A5 - - Google Patents
Info
- Publication number
- CH606023A5 CH606023A5 CH1680175A CH1680175A CH606023A5 CH 606023 A5 CH606023 A5 CH 606023A5 CH 1680175 A CH1680175 A CH 1680175A CH 1680175 A CH1680175 A CH 1680175A CH 606023 A5 CH606023 A5 CH 606023A5
- Authority
- CH
- Switzerland
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7443221A FR2296418B1 (US07935154-20110503-C00018.png) | 1974-12-30 | 1974-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH606023A5 true CH606023A5 (US07935154-20110503-C00018.png) | 1978-10-13 |
Family
ID=9146736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1680175A CH606023A5 (US07935154-20110503-C00018.png) | 1974-12-30 | 1975-12-24 |
Country Status (10)
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2296418B1 (US07935154-20110503-C00018.png) * | 1974-12-30 | 1978-07-21 | Anvar | |
| GR68940B (US07935154-20110503-C00018.png) * | 1977-01-19 | 1982-03-29 | Lilly Co Eli | |
| US4115388A (en) * | 1977-03-30 | 1978-09-19 | Eli Lilly And Company | 3'-Oxygenated derivatives of 4'-deoxy VLB "A" and "B" and related 1-formyl compounds |
| HU180924B (en) | 1977-05-20 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing leurosine-type alkaloides |
| HU181874B (en) * | 1977-08-08 | 1983-11-28 | Lilly Co Eli | Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine |
| US4191688A (en) | 1977-08-08 | 1980-03-04 | Eli Lilly And Company | Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine |
| US4195022A (en) | 1978-03-27 | 1980-03-25 | Eli Lilly And Company | 4-Desacetoxy-4α-hydroxyvinblastine and related compounds |
| FR2443470A1 (fr) * | 1978-12-08 | 1980-07-04 | Anvar | Nouveau procede de synthese de la vinblastine et de la leurosidine |
| US4841045A (en) * | 1985-03-12 | 1989-06-20 | University Of Vermont & State Agricultural College | Synthesis of vinblastine and vincristine type compounds |
| US4897477A (en) * | 1985-03-12 | 1990-01-30 | University Of Vermont & State Agricultural College | Synthesis of vinblastine and vincristine type compounds |
| WO1986005491A1 (en) * | 1985-03-12 | 1986-09-25 | The University Of Vermont And State Agricultural C | Synthesis of vinblastine and vincristine type compounds |
| US4778885A (en) * | 1986-09-18 | 1988-10-18 | Allelix Inc. | Production of alkaloid dimers using ferric ion |
| CA1341261C (en) * | 1987-01-22 | 2001-06-26 | James P. Kutney | Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine |
| AU1066888A (en) * | 1987-01-22 | 1988-08-04 | University Of British Columbia, The | Process for the synthesis of vinblastine and vincristine |
| US5047528A (en) * | 1987-01-22 | 1991-09-10 | University Of Bristish Columbia | Process of synthesis of vinblastine and vincristine |
| USRE37449E1 (en) | 1987-02-06 | 2001-11-13 | University Of British Columbia | Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine |
| US5037977A (en) * | 1988-08-11 | 1991-08-06 | Mitsui Petrochemical Industries Ltd. | Method for production of dimeric alkaloids |
| FR2707988B1 (fr) * | 1993-07-21 | 1995-10-13 | Pf Medicament | Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant. |
| IL123220A0 (en) | 1995-08-08 | 1998-09-24 | Albany Medical College | Ibogamine congeners |
| FR2779146B1 (fr) | 1998-06-02 | 2002-01-18 | Roowin | Nouveaux derives de vinca-alcaloides et procedes de preparation |
| AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| US7235564B2 (en) * | 2003-12-04 | 2007-06-26 | Amr Technology, Inc. | Vinorelbine derivatives |
| NZ547370A (en) * | 2003-12-04 | 2010-09-30 | Amr Technology Inc | Vinca derivatives |
| WO2008033930A2 (en) * | 2006-09-12 | 2008-03-20 | Amr Technology, Inc. | Vinca derivatives |
| US20080125451A1 (en) * | 2006-09-12 | 2008-05-29 | Amr Technology, Inc. | Vinorelbine derivatives |
| US9394294B2 (en) | 2010-05-11 | 2016-07-19 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
| US8765737B1 (en) | 2010-05-11 | 2014-07-01 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
| US8802832B2 (en) | 2010-06-22 | 2014-08-12 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
| US8637648B1 (en) | 2010-06-22 | 2014-01-28 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
| RU2586296C2 (ru) | 2010-07-23 | 2016-06-10 | Демеркс, Инк. | Композиции норибогаина |
| EP2481740B1 (en) | 2011-01-26 | 2015-11-04 | DemeRx, Inc. | Methods and compositions for preparing noribogaine from voacangine |
| US8742096B2 (en) | 2011-03-28 | 2014-06-03 | Demerx, Inc. | Methods and compositions for preparing noribogaine from voacangine |
| US9617274B1 (en) | 2011-08-26 | 2017-04-11 | Demerx, Inc. | Synthetic noribogaine |
| JP2015500833A (ja) | 2011-12-09 | 2015-01-08 | デメレックス， インコーポレイテッド | ノルイボガインのリン酸エステル |
| US20130178618A1 (en) | 2012-01-10 | 2013-07-11 | William Allen Boulanger | Novel pharmaceutical intermediates and methods for preparing the same |
| CA2858820C (en) | 2012-01-25 | 2021-08-17 | Demerx, Inc. | Synthetic voacangine |
| US8940728B2 (en) | 2012-12-20 | 2015-01-27 | Demerx, Inc. | Substituted noribogaine |
| WO2014098877A1 (en) | 2012-12-20 | 2014-06-26 | Demerx, Inc. | Substituted noribogaine |
| US9045481B2 (en) | 2012-12-20 | 2015-06-02 | Demerx, Inc. | Substituted noribogaine |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH77A (de) * | 1889-01-09 | Christian Herren | Wurzelschneidmaschine | |
| FR2210393B1 (US07935154-20110503-C00018.png) * | 1972-12-19 | 1976-07-02 | Richter Gedeon Vegyeszet | |
| HU165986B (US07935154-20110503-C00018.png) * | 1973-02-16 | 1974-12-28 | ||
| FR2296418B1 (US07935154-20110503-C00018.png) * | 1974-12-30 | 1978-07-21 | Anvar | |
| US4279817A (en) * | 1975-05-30 | 1981-07-21 | The United States Of America As Represented By The Department Of Health & Human Services | Method for producing dimer alkaloids |
| US4029663A (en) * | 1975-07-10 | 1977-06-14 | Eli Lilly And Company | Dimeric anhydro-vinca derivatives |
| US4143041A (en) * | 1977-01-19 | 1979-03-06 | Eli Lilly And Company | 4'-Deoxyvincristine and related compounds |
| HU180924B (en) * | 1977-05-20 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing leurosine-type alkaloides |
| HU178084B (en) * | 1977-05-31 | 1982-03-28 | Richter Gedeon Vegyeszet | New process for the extraction of native vindoline,catharantine,3',4'-anhydrovinblastine,leurosine and,if desired,of other diinodle alkaloids from vinca rosea l.drogue |
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1974
- 1974-12-30 FR FR7443221A patent/FR2296418B1/fr not_active Expired
-
1975
- 1975-12-23 DE DE19752558124 patent/DE2558124A1/de active Granted
- 1975-12-23 GB GB52570/75A patent/GB1536407A/en not_active Expired
- 1975-12-24 BE BE163109A patent/BE837073A/xx not_active IP Right Cessation
- 1975-12-24 CH CH1680175A patent/CH606023A5/xx not_active IP Right Cessation
- 1975-12-30 JP JP50159649A patent/JPS6056719B2/ja not_active Expired
- 1975-12-30 HU HU75AA840A patent/HU177154B/hu unknown
- 1975-12-30 NL NLAANVRAGE7515193,A patent/NL184418C/xx not_active IP Right Cessation
- 1975-12-31 CA CA243,046A patent/CA1132544A/en not_active Expired
-
1981
- 1981-06-18 US US06/275,050 patent/US4769453A/en not_active Expired - Lifetime
-
1986
- 1986-04-29 US US06/857,075 patent/US4737586A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL184418C (nl) | 1989-07-17 |
| FR2296418A1 (US07935154-20110503-C00018.png) | 1976-07-30 |
| JPS5188999A (en) | 1976-08-04 |
| NL7515193A (nl) | 1976-07-02 |
| DE2558124A1 (de) | 1976-07-01 |
| BE837073A (fr) | 1976-06-24 |
| DE2558124C2 (US07935154-20110503-C00018.png) | 1991-04-18 |
| HU177154B (en) | 1981-08-28 |
| JPS6056719B2 (ja) | 1985-12-11 |
| US4769453A (en) | 1988-09-06 |
| NL184418B (nl) | 1989-02-16 |
| FR2296418B1 (US07935154-20110503-C00018.png) | 1978-07-21 |
| US4737586A (en) | 1988-04-12 |
| GB1536407A (en) | 1978-12-20 |
| CA1132544A (en) | 1982-09-28 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUE | Assignment |
Owner name: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS |
|
| PL | Patent ceased |