CH594626A5 - - Google Patents

Info

Publication number
CH594626A5
CH594626A5 CH661874A CH661874A CH594626A5 CH 594626 A5 CH594626 A5 CH 594626A5 CH 661874 A CH661874 A CH 661874A CH 661874 A CH661874 A CH 661874A CH 594626 A5 CH594626 A5 CH 594626A5
Authority
CH
Switzerland
Application number
CH661874A
Inventor
Knut A Dr Jaeggi
Franz Dr Ostermayer
Herbert Dr Schroeter
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH661874A priority Critical patent/CH594626A5/xx
Priority to CH658274A priority patent/CH591448A5/xx
Priority to CH156177A priority patent/CH592625A5/xx
Priority to SE7504375A priority patent/SE7504375L/xx
Priority to NL7504864A priority patent/NL7504864A/xx
Priority to GB18491/75A priority patent/GB1493006A/en
Priority to US05/574,785 priority patent/US4027027A/en
Priority to DE19752520910 priority patent/DE2520910A1/de
Priority to CA226,694A priority patent/CA1067077A/en
Priority to AU81045/75A priority patent/AU8104575A/en
Priority to FR7514655A priority patent/FR2270863B1/fr
Priority to BE156276A priority patent/BE828989A/xx
Priority to AT364675A priority patent/AT345288B/de
Priority to HU75CI00001575A priority patent/HU172769B/hu
Priority to JP50056214A priority patent/JPS50154213A/ja
Priority to CH4537776A priority patent/CH590235A5/de
Priority to AT171377A priority patent/AT345292B/de
Priority to AT171077A priority patent/AT345291B/de
Priority to US05/777,222 priority patent/US4139623A/en
Publication of CH594626A5 publication Critical patent/CH594626A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH661874A 1974-05-14 1974-05-14 CH594626A5 (cs)

Priority Applications (19)

Application Number Priority Date Filing Date Title
CH661874A CH594626A5 (cs) 1974-05-14 1974-05-14
CH658274A CH591448A5 (cs) 1974-05-14 1974-05-14
CH156177A CH592625A5 (cs) 1974-05-14 1974-05-14
SE7504375A SE7504375L (sv) 1974-05-14 1975-04-16 Cykliskt substituerade derivat av 1-amino-2-propanol.
NL7504864A NL7504864A (nl) 1974-05-14 1975-04-24 Cyclisch gesubstitueerde derivaten van 1-amino- -2-propanol.
GB18491/75A GB1493006A (en) 1974-05-14 1975-05-02 Cyclic-substituted derivatives of 1-amino-2-propanol
US05/574,785 US4027027A (en) 1974-05-14 1975-05-05 Pyridyloxyalkyleneamino-phenoxy-propanol-2-compounds
DE19752520910 DE2520910A1 (de) 1974-05-14 1975-05-10 Cyclisch substituierte derivate des 1-amino-2-propanol
CA226,694A CA1067077A (en) 1974-05-14 1975-05-12 Process for the manufacture of cyclic-substituted derivatives of 1-amino-2-propanol
AU81045/75A AU8104575A (en) 1974-05-14 1975-05-12 Cyclic-substituted derivatives of 1-amino-2-propanol
FR7514655A FR2270863B1 (cs) 1974-05-14 1975-05-12
BE156276A BE828989A (fr) 1974-05-14 1975-05-13 Derives du 1-amino-2-propanol a substituants cycliques
AT364675A AT345288B (de) 1974-05-14 1975-05-13 Verfahren zur herstellung von neuen cyclisch substituierten derivaten des 1-amino-2-propanols und deren salzen
HU75CI00001575A HU172769B (hu) 1974-05-14 1975-05-13 Sposob poluchenija proizvodnykh 1-amino-2-propanola zamehhjonnogo ciklicheskimi gruppami
JP50056214A JPS50154213A (cs) 1974-05-14 1975-05-14
CH4537776A CH590235A5 (en) 1974-05-14 1977-01-14 Di-aryl substd.-1-amino-2-propanols - as beta receptor blocking agents esp. cardioselective blocking agents, also intermediates
AT171377A AT345292B (de) 1974-05-14 1977-03-14 Verfahren zur herstellung von neuen cyclisch substituierten derivaten des 1-amino-2-propanols und deren salzen
AT171077A AT345291B (de) 1974-05-14 1977-03-14 Verfahren zur herstellung von neuen cyclisch substituierten derivaten des 1-amino-2-propanols und deren salzen
US05/777,222 US4139623A (en) 1974-05-14 1977-03-14 Cyclic-substituted derivatives of 1-amino-2-propanol

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH658274A CH591448A5 (cs) 1974-05-14 1974-05-14
CH156177A CH592625A5 (cs) 1974-05-14 1974-05-14
CH661874A CH594626A5 (cs) 1974-05-14 1974-05-14

Publications (1)

Publication Number Publication Date
CH594626A5 true CH594626A5 (cs) 1978-01-13

Family

ID=27173079

Family Applications (3)

Application Number Title Priority Date Filing Date
CH661874A CH594626A5 (cs) 1974-05-14 1974-05-14
CH658274A CH591448A5 (cs) 1974-05-14 1974-05-14
CH156177A CH592625A5 (cs) 1974-05-14 1974-05-14

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH658274A CH591448A5 (cs) 1974-05-14 1974-05-14
CH156177A CH592625A5 (cs) 1974-05-14 1974-05-14

Country Status (12)

Country Link
US (1) US4027027A (cs)
JP (1) JPS50154213A (cs)
AT (1) AT345288B (cs)
AU (1) AU8104575A (cs)
BE (1) BE828989A (cs)
CA (1) CA1067077A (cs)
CH (3) CH594626A5 (cs)
DE (1) DE2520910A1 (cs)
FR (1) FR2270863B1 (cs)
GB (1) GB1493006A (cs)
NL (1) NL7504864A (cs)
SE (1) SE7504375L (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193995A (en) * 1972-05-05 1980-03-18 Merck Sharp & Dohme (I.A.) Corp. 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds and compositions
US4195090A (en) * 1973-02-20 1980-03-25 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith
US4853383A (en) * 1975-03-03 1989-08-01 Merck & Co., Inc. β-blocking substituted imidazoles
US4440774A (en) * 1975-03-03 1984-04-03 Merck & Co., Inc. 3-Amino-2-hydroxypropoxyaryl imidazole derivatives
US4263323A (en) * 1976-10-07 1981-04-21 Aktiebolaget Hassle β-Receptor blocking compounds and treatment of cardiovascular disorders therewith
DE2711655A1 (de) * 1977-03-17 1978-09-21 Basf Ag Pyridinyl-aminoalkylaether
FI782133A (fi) * 1977-07-08 1979-01-09 Ciba Geigy Ag Piperidino-propanoler och foerfarande foer deras framstaellning
US4235919A (en) 1977-07-21 1980-11-25 Sandoz Ltd. 1-(Indol-4-yloxy)-3-(2-substituted amino)-2-propanols and pharmaceutical use thereof
US4263325A (en) * 1977-10-05 1981-04-21 Aktiebolaget Hassle β-Receptor blocking compounds and treatment of cardiovascular disorders therewith
DK267779A (da) * 1978-06-27 1979-12-28 Merck & Co Inc Fr&mgangsmaade til fremstilling af n-aralkylamino-propoxycyanopyridiner
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
US4208416A (en) * 1978-06-27 1980-06-17 Merck & Co., Inc. N-Aralkyl containing cyanopyridines
JPS55124742A (en) 1979-03-20 1980-09-26 Kyowa Hakko Kogyo Co Ltd Novel aminoalcohol derivative
IT1165040B (it) * 1979-04-23 1987-04-22 Isf Spa Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione
DE3048487A1 (de) * 1980-12-22 1982-07-29 Cassella Ag, 6000 Frankfurt Basisch substituierte pyridazine, ihre herstellung und ihre verwendung
US4599333A (en) * 1982-06-14 1986-07-08 Teikoku Hormone Mfg. Co., Ltd. Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament
US4598149A (en) * 1984-03-02 1986-07-01 Merck & Co., Inc. 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents
US4920134A (en) * 1987-08-07 1990-04-24 Takeda Chemical Industries, Ltd. 2-O-pyrimidinyl glycerol derivatives
US5221674A (en) * 1989-06-19 1993-06-22 Teikoku Hormone Mfg. Co., Ltd. Pyridazinone derivatives
NZ234087A (en) * 1989-06-19 1991-08-27 Teikoku Hormone Mfg Co Ltd 2-(3-aryloxy(2-hydroxy-propylamino))-2-methylpropyl- aminophenyl pyridazine derivatives
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
CA2314458A1 (en) * 1999-08-02 2001-02-02 Kazumi Okuro Process for production of 3-(3-pyridyl)-1-propanol derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU65414A1 (cs) * 1972-05-24 1973-12-04

Also Published As

Publication number Publication date
NL7504864A (nl) 1975-11-18
ATA364675A (de) 1978-01-15
FR2270863B1 (cs) 1979-05-18
BE828989A (fr) 1975-11-13
US4027027A (en) 1977-05-31
FR2270863A1 (cs) 1975-12-12
AU8104575A (en) 1976-11-18
CA1067077A (en) 1979-11-27
CH591448A5 (cs) 1977-09-15
JPS50154213A (cs) 1975-12-12
AT345288B (de) 1978-09-11
DE2520910A1 (de) 1975-12-04
SE7504375L (sv) 1975-11-17
CH592625A5 (cs) 1977-10-31
GB1493006A (en) 1977-11-23

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Legal Events

Date Code Title Description
PL Patent ceased