CH567478A5 - 1-(2-(2-phenylpropionyl) tetrahydroisoquinolinyl-7-sulphonyl)-3- - cyclohexylamino-ureas prepn - useful as hypoglycaemics - Google Patents
1-(2-(2-phenylpropionyl) tetrahydroisoquinolinyl-7-sulphonyl)-3- - cyclohexylamino-ureas prepn - useful as hypoglycaemicsInfo
- Publication number
- CH567478A5 CH567478A5 CH1787771A CH1787771A CH567478A5 CH 567478 A5 CH567478 A5 CH 567478A5 CH 1787771 A CH1787771 A CH 1787771A CH 1787771 A CH1787771 A CH 1787771A CH 567478 A5 CH567478 A5 CH 567478A5
- Authority
- CH
- Switzerland
- Prior art keywords
- substd
- opt
- reacting
- cyclohexylamino
- aralkyl
- Prior art date
Links
- 230000002218 hypoglycaemic effect Effects 0.000 title 1
- PAFZNILMFXTMIY-UHFFFAOYSA-N cyclohexylamine Chemical compound NC1CCCCC1 PAFZNILMFXTMIY-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- -1 alkali metal salt Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- XEIONDMOAYQBOA-UHFFFAOYSA-N 1-cyclohexyl-3-(1,2,3,4-tetrahydroisoquinolin-7-ylsulfonyl)urea Chemical compound C1NCCC2=CC=C(C=C12)S(=O)(=O)NC(=O)NC1CCCCC1 XEIONDMOAYQBOA-UHFFFAOYSA-N 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702060720 DE2060720A1 (de) | 1969-07-01 | 1970-12-10 | Neue Verfahren zur Herstellung von Sulfonylharnstoffen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH567478A5 true CH567478A5 (en) | 1975-10-15 |
Family
ID=5790525
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1787771A CH567478A5 (en) | 1970-12-10 | 1971-12-08 | 1-(2-(2-phenylpropionyl) tetrahydroisoquinolinyl-7-sulphonyl)-3- - cyclohexylamino-ureas prepn - useful as hypoglycaemics |
| CH1459874A CH568292A5 (enrdf_load_stackoverflow) | 1970-12-10 | 1971-12-08 | |
| CH1460374A CH568293A5 (enrdf_load_stackoverflow) | 1970-12-10 | 1971-12-08 | |
| CH1460074A CH567479A5 (enrdf_load_stackoverflow) | 1970-12-10 | 1971-12-08 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1459874A CH568292A5 (enrdf_load_stackoverflow) | 1970-12-10 | 1971-12-08 | |
| CH1460374A CH568293A5 (enrdf_load_stackoverflow) | 1970-12-10 | 1971-12-08 | |
| CH1460074A CH567479A5 (enrdf_load_stackoverflow) | 1970-12-10 | 1971-12-08 |
Country Status (9)
| Country | Link |
|---|---|
| AT (7) | AT317913B (enrdf_load_stackoverflow) |
| BG (6) | BG20573A3 (enrdf_load_stackoverflow) |
| CA (1) | CA960675A (enrdf_load_stackoverflow) |
| CH (4) | CH567478A5 (enrdf_load_stackoverflow) |
| DD (1) | DD96068A5 (enrdf_load_stackoverflow) |
| ES (7) | ES397789A1 (enrdf_load_stackoverflow) |
| HU (1) | HU163804B (enrdf_load_stackoverflow) |
| RO (1) | RO61566A (enrdf_load_stackoverflow) |
| SE (1) | SE378244B (enrdf_load_stackoverflow) |
-
1970
- 1970-12-29 SE SE1767770A patent/SE378244B/xx unknown
-
1971
- 1971-12-08 HU HUTO000864 patent/HU163804B/hu unknown
- 1971-12-08 CH CH1787771A patent/CH567478A5/xx unknown
- 1971-12-08 RO RO6899471A patent/RO61566A/ro unknown
- 1971-12-08 CH CH1459874A patent/CH568292A5/xx not_active IP Right Cessation
- 1971-12-08 CH CH1460374A patent/CH568293A5/xx not_active IP Right Cessation
- 1971-12-08 CH CH1460074A patent/CH567479A5/xx not_active IP Right Cessation
- 1971-12-09 AT AT00264/73A patent/AT317913B/de not_active IP Right Cessation
- 1971-12-09 DD DD15946471A patent/DD96068A5/xx unknown
- 1971-12-09 BG BG022935A patent/BG20573A3/xx unknown
- 1971-12-09 BG BG022931A patent/BG20786A3/xx unknown
- 1971-12-09 BG BG022936A patent/BG19137A3/xx unknown
- 1971-12-09 BG BG2293371A patent/BG20572A3/xx unknown
- 1971-12-09 AT AT00267/73A patent/AT317916B/de not_active IP Right Cessation
- 1971-12-09 ES ES397789A patent/ES397789A1/es not_active Expired
- 1971-12-09 AT AT00263/73A patent/AT317912B/de not_active IP Right Cessation
- 1971-12-09 AT AT1060671A patent/AT313914B/de not_active IP Right Cessation
- 1971-12-09 AT AT00266/73A patent/AT317915B/de not_active IP Right Cessation
- 1971-12-09 BG BG022934A patent/BG20343A3/xx unknown
- 1971-12-09 CA CA129,728A patent/CA960675A/en not_active Expired
- 1971-12-09 BG BG022932A patent/BG20571A3/xx unknown
- 1971-12-09 AT AT00265/73A patent/AT317914B/de not_active IP Right Cessation
- 1971-12-09 AT AT00268/73A patent/AT317917B/de not_active IP Right Cessation
-
1972
- 1972-01-18 ES ES398955A patent/ES398955A1/es not_active Expired
- 1972-01-18 ES ES398954A patent/ES398954A1/es not_active Expired
- 1972-01-18 ES ES72398953A patent/ES398953A1/es not_active Expired
- 1972-01-18 ES ES398956A patent/ES398956A1/es not_active Expired
- 1972-01-18 ES ES398958A patent/ES398958A1/es not_active Expired
- 1972-01-18 ES ES398957A patent/ES398957A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BG19137A3 (bg) | 1975-04-30 |
| BG20572A3 (enrdf_load_stackoverflow) | 1975-12-05 |
| RO61566A (enrdf_load_stackoverflow) | 1977-01-15 |
| CH567479A5 (enrdf_load_stackoverflow) | 1975-10-15 |
| AT313914B (de) | 1974-03-11 |
| ES398958A1 (es) | 1974-10-16 |
| CA960675A (en) | 1975-01-07 |
| AT317915B (de) | 1974-09-25 |
| ES398955A1 (es) | 1974-10-16 |
| AT317914B (de) | 1974-09-25 |
| CH568293A5 (enrdf_load_stackoverflow) | 1975-10-31 |
| CH568292A5 (enrdf_load_stackoverflow) | 1975-10-31 |
| ES398954A1 (es) | 1974-10-01 |
| SE378244B (enrdf_load_stackoverflow) | 1975-08-25 |
| DD96068A5 (enrdf_load_stackoverflow) | 1973-03-05 |
| ES397789A1 (es) | 1974-06-01 |
| BG20571A3 (bg) | 1975-12-05 |
| BG20786A3 (bg) | 1975-12-20 |
| ES398957A1 (es) | 1974-10-16 |
| BG20573A3 (bg) | 1975-12-05 |
| AT317913B (de) | 1974-09-25 |
| HU163804B (enrdf_load_stackoverflow) | 1973-10-27 |
| BG20343A3 (bg) | 1975-11-05 |
| AT317912B (de) | 1974-09-25 |
| AT317917B (de) | 1974-09-25 |
| ES398956A1 (es) | 1974-10-16 |
| AT317916B (de) | 1974-09-25 |
| ES398953A1 (es) | 1974-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PLZ | Patent of addition ceased |