CH553787A - Verfahren zur herstellung von imidazolderivaten. - Google Patents
Verfahren zur herstellung von imidazolderivaten.Info
- Publication number
- CH553787A CH553787A CH522767A CH522767A CH553787A CH 553787 A CH553787 A CH 553787A CH 522767 A CH522767 A CH 522767A CH 522767 A CH522767 A CH 522767A CH 553787 A CH553787 A CH 553787A
- Authority
- CH
- Switzerland
- Prior art keywords
- production
- imidazole derivatives
- imidazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54306666A | 1966-04-18 | 1966-04-18 | |
| US85755669A | 1969-09-12 | 1969-09-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH553787A true CH553787A (de) | 1974-09-13 |
Family
ID=27067226
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH522767A CH553787A (de) | 1966-04-18 | 1967-04-12 | Verfahren zur herstellung von imidazolderivaten. |
| CH1905969A CH561698A5 (fi) | 1966-04-18 | 1967-04-12 | |
| CH1905869A CH565771A5 (fi) | 1966-04-18 | 1967-04-12 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1905969A CH561698A5 (fi) | 1966-04-18 | 1967-04-12 | |
| CH1905869A CH565771A5 (fi) | 1966-04-18 | 1967-04-12 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US3505349A (fi) |
| BE (1) | BE696952A (fi) |
| CH (3) | CH553787A (fi) |
| DE (1) | DE1695186B2 (fi) |
| DK (1) | DK137854B (fi) |
| ES (1) | ES339419A1 (fi) |
| FI (1) | FI49037C (fi) |
| FR (1) | FR6767M (fi) |
| GB (1) | GB1138529A (fi) |
| IL (1) | IL27805A (fi) |
| NL (1) | NL150787B (fi) |
| NO (1) | NO124072B (fi) |
| PH (1) | PH9423A (fi) |
| SE (1) | SE346001B (fi) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1079275B (de) * | 1958-09-05 | 1960-04-07 | Praemeta Praez Smetall Und Kun | Schnepper, insbesondere zur Blutentnahme |
| FR2054504B1 (fi) * | 1969-07-18 | 1973-06-08 | Rhone Poulenc Sa | |
| DE2022206C3 (de) * | 1970-05-06 | 1979-01-25 | Bayer Ag, 5090 Leverkusen | Basisch substituierte Diphenylazolyl-essigsäureester, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
| US3940484A (en) * | 1971-12-07 | 1976-02-24 | The Boots Company Limited | Insecticidal compositions and methods of combatting insects using substituted imidazoles |
| DE2306495A1 (de) * | 1973-02-09 | 1974-08-15 | Bayer Ag | Fungizide mittel |
| DE2553021A1 (de) * | 1974-12-06 | 1976-06-10 | Sandoz Ag | Organische verbindungen, ihre verwendung und herstellung |
| IE47132B1 (en) * | 1977-08-19 | 1983-12-28 | Roche Products Ltd | Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture |
| DE3070778D1 (en) * | 1979-08-11 | 1985-07-25 | Bayer Ag | Antimycotic agents with enhanced release of the active ingredients |
| US4371540A (en) * | 1979-09-14 | 1983-02-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells |
| ZW8781A1 (en) * | 1980-05-23 | 1981-12-16 | Hoffmann La Roche | 2-nitroimidazoles and preparation thereof |
| US5192784A (en) * | 1991-06-03 | 1993-03-09 | Du Pont Merck Pharmaceutical Company | Etanidazole injectable solution |
| US5366987A (en) * | 1991-08-22 | 1994-11-22 | Warner-Lambert Company | Isoxazolyl-substituted alkyl amide ACAT inhibitors |
| US6252087B1 (en) * | 1992-11-19 | 2001-06-26 | The Trustees Of The University Of Pennsylvania | Nitroaromatic compounds for the detection of hypoxia |
| EP0669913B1 (en) * | 1992-11-19 | 2003-03-05 | The Trustees Of The University Of Pennsylvania | Detection of hypoxia |
| US6855828B1 (en) | 1992-11-19 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Detection of hypoxia |
| US5721265A (en) * | 1994-08-05 | 1998-02-24 | Sri International | Fluorinated 2-nitroimidazole analogs for detecting hypoxic tumor cells |
| US20050026974A1 (en) * | 1996-02-08 | 2005-02-03 | Trustees Of The University Of Pennsylvania | Detection of hypoxia |
| CA2379974C (en) * | 1999-07-21 | 2011-10-25 | The Trustees Of The University Of Pennsylvania | Preparation of compounds useful for the detection of hypoxia |
| US7230115B1 (en) | 1999-07-21 | 2007-06-12 | The Trustees Of The University Of Pennsylvania | Preparation of compounds useful for the detection of hypoxia |
| EP2010493B1 (en) * | 2006-04-12 | 2016-01-27 | Merck Sharp & Dohme Corp. | Pyridyl amide t-type calcium channel antagonists |
| WO2009054983A1 (en) * | 2007-10-24 | 2009-04-30 | Merck & Co., Inc. | Heterocycle amide t-type calcium channel antagonists |
| EP2212291B1 (en) * | 2007-10-24 | 2014-06-04 | Merck Sharp & Dohme Corp. | Heterocycle phenyl amide t-type calcium channel antagonists |
| US9655975B2 (en) | 2012-02-13 | 2017-05-23 | University Of Tsukuba | Prodrug using nitroimidazole |
| SV2013004584A (es) * | 2013-11-19 | 2015-09-07 | Mini De Educacion | Procedimiento de manufactura para obtención de de n-bencil-2-(2-nitro-1h-imidazol-1-il)acetamida |
| WO2017205622A1 (en) * | 2016-05-25 | 2017-11-30 | Savant Neglected Diseases, Llc | Method of making benznidazole |
| WO2019240671A1 (es) * | 2018-06-11 | 2019-12-19 | Ministerio De Educación, Ciencia Y Tecnología | Método de manufactura para la producción de benznidazol y su escalado industrial |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3065133A (en) * | 1956-09-28 | 1962-11-20 | Rhone Poulenc Sa | Imidazoles for the control of histomoniasis |
| US3037909A (en) * | 1960-06-29 | 1962-06-05 | Merck & Co Inc | 1-methyl-5-nitroimidazole for enterohepatitis |
| NL299109A (fi) * | 1962-11-05 |
-
1966
- 1966-04-18 US US543066A patent/US3505349A/en not_active Expired - Lifetime
-
1967
- 1967-04-12 PH PH8144*UA patent/PH9423A/en unknown
- 1967-04-12 CH CH522767A patent/CH553787A/xx not_active IP Right Cessation
- 1967-04-12 CH CH1905969A patent/CH561698A5/xx not_active IP Right Cessation
- 1967-04-12 CH CH1905869A patent/CH565771A5/xx not_active IP Right Cessation
- 1967-04-13 BE BE696952D patent/BE696952A/xx not_active IP Right Cessation
- 1967-04-14 DE DE1967H0062438 patent/DE1695186B2/de active Granted
- 1967-04-17 IL IL27805A patent/IL27805A/en unknown
- 1967-04-17 FR FR102906A patent/FR6767M/fr not_active Expired
- 1967-04-17 NO NO167757A patent/NO124072B/no unknown
- 1967-04-17 ES ES339419A patent/ES339419A1/es not_active Expired
- 1967-04-17 GB GB17439/67A patent/GB1138529A/en not_active Expired
- 1967-04-18 FI FI671146A patent/FI49037C/fi active
- 1967-04-18 NL NL676705439A patent/NL150787B/xx not_active IP Right Cessation
- 1967-04-18 SE SE5386/67A patent/SE346001B/xx unknown
- 1967-04-18 DK DK208567AA patent/DK137854B/da unknown
-
1969
- 1969-09-12 US US857556A patent/US3679698A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE1695186B2 (de) | 1976-12-02 |
| GB1138529A (en) | 1969-01-01 |
| DK137854B (da) | 1978-05-22 |
| PH9423A (en) | 1975-11-14 |
| NO124072B (fi) | 1972-02-28 |
| FI49037C (fi) | 1975-03-10 |
| IL27805A (en) | 1972-04-27 |
| DE1695186A1 (de) | 1971-04-08 |
| CH565771A5 (fi) | 1975-08-29 |
| CH561698A5 (fi) | 1975-05-15 |
| FI49037B (fi) | 1974-12-02 |
| ES339419A1 (es) | 1968-05-16 |
| SE346001B (fi) | 1972-06-19 |
| US3679698A (en) | 1972-07-25 |
| US3505349A (en) | 1970-04-07 |
| BE696952A (fi) | 1967-10-13 |
| DK137854C (fi) | 1978-10-23 |
| NL6705439A (fi) | 1967-10-19 |
| FR6767M (fi) | 1969-03-10 |
| NL150787B (nl) | 1976-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |