CH547785A - Verfahren zur herstellung von 2',3'(alpha)-tetrahydrofuran-2'spiro-17(6,7(alpha)-dihalogenmethylen-1,2(alpha)-methylen-4-androsten-3-on)-derivaten. - Google Patents

Verfahren zur herstellung von 2',3'(alpha)-tetrahydrofuran-2'spiro-17(6,7(alpha)-dihalogenmethylen-1,2(alpha)-methylen-4-androsten-3-on)-derivaten.

Info

Publication number
CH547785A
CH547785A CH327973A CH327973A CH547785A CH 547785 A CH547785 A CH 547785A CH 327973 A CH327973 A CH 327973A CH 327973 A CH327973 A CH 327973A CH 547785 A CH547785 A CH 547785A
Authority
CH
Switzerland
Prior art keywords
alpha
dihalogenmethylene
androstene
spiro
tetrahydrofuran
Prior art date
Application number
CH327973A
Other languages
German (de)
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH547785A publication Critical patent/CH547785A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH327973A 1969-05-14 1970-05-06 Verfahren zur herstellung von 2',3'(alpha)-tetrahydrofuran-2'spiro-17(6,7(alpha)-dihalogenmethylen-1,2(alpha)-methylen-4-androsten-3-on)-derivaten. CH547785A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82467269A 1969-05-14 1969-05-14
US2118370A 1970-03-19 1970-03-19

Publications (1)

Publication Number Publication Date
CH547785A true CH547785A (de) 1974-04-11

Family

ID=26694377

Family Applications (2)

Application Number Title Priority Date Filing Date
CH327973A CH547785A (de) 1969-05-14 1970-05-06 Verfahren zur herstellung von 2',3'(alpha)-tetrahydrofuran-2'spiro-17(6,7(alpha)-dihalogenmethylen-1,2(alpha)-methylen-4-androsten-3-on)-derivaten.
CH683870A CH547792A (de) 1969-05-14 1970-05-06 Verfahren zur herstellung von spiro-steroiden.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH683870A CH547792A (de) 1969-05-14 1970-05-06 Verfahren zur herstellung von spiro-steroiden.

Country Status (17)

Country Link
JP (1) JPS532865B1 (enrdf_load_stackoverflow)
AR (1) AR192305A1 (enrdf_load_stackoverflow)
BE (1) BE750330A (enrdf_load_stackoverflow)
CA (1) CA926385A (enrdf_load_stackoverflow)
CH (2) CH547785A (enrdf_load_stackoverflow)
CS (2) CS151552B2 (enrdf_load_stackoverflow)
DE (1) DE2023450C3 (enrdf_load_stackoverflow)
DK (3) DK126992B (enrdf_load_stackoverflow)
FI (2) FI47355C (enrdf_load_stackoverflow)
FR (1) FR2051526B1 (enrdf_load_stackoverflow)
GB (1) GB1265444A (enrdf_load_stackoverflow)
IE (1) IE34194B1 (enrdf_load_stackoverflow)
IL (1) IL34431A (enrdf_load_stackoverflow)
NL (1) NL168844C (enrdf_load_stackoverflow)
NO (1) NO131131C (enrdf_load_stackoverflow)
SE (2) SE366305B (enrdf_load_stackoverflow)
YU (1) YU34052B (enrdf_load_stackoverflow)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes

Also Published As

Publication number Publication date
DK127880C (da) 1974-06-10
CH547792A (de) 1974-04-11
YU117670A (en) 1978-05-15
GB1265444A (enrdf_load_stackoverflow) 1972-03-01
FI47355C (fi) 1973-11-12
DK127880B (enrdf_load_stackoverflow) 1974-01-28
FR2051526B1 (enrdf_load_stackoverflow) 1974-04-12
CS151551B2 (enrdf_load_stackoverflow) 1973-10-19
CA926385A (en) 1973-05-15
NL168844C (nl) 1982-05-17
FR2051526A1 (enrdf_load_stackoverflow) 1971-04-09
IE34194L (en) 1970-11-14
AR192305A1 (es) 1973-02-14
NO131131C (enrdf_load_stackoverflow) 1975-04-09
NL7006474A (enrdf_load_stackoverflow) 1970-11-17
DK127505B (da) 1973-11-19
SE386904B (sv) 1976-08-23
IE34194B1 (en) 1975-03-05
FI47885C (fi) 1974-04-10
CS151552B2 (enrdf_load_stackoverflow) 1973-10-19
DE2023450B2 (de) 1978-10-05
SE366305B (enrdf_load_stackoverflow) 1974-04-22
DE2023450C3 (de) 1979-05-31
IL34431A (en) 1974-03-14
DK126992B (da) 1973-09-10
NL168844B (nl) 1981-12-16
DE2023450A1 (de) 1971-01-14
JPS532865B1 (enrdf_load_stackoverflow) 1978-02-01
IL34431A0 (en) 1970-07-19
FI47355B (enrdf_load_stackoverflow) 1973-07-31
YU34052B (en) 1978-10-31
BE750330A (fr) 1970-11-13
NO131131B (enrdf_load_stackoverflow) 1974-12-30
FI47885B (enrdf_load_stackoverflow) 1974-01-02

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Legal Events

Date Code Title Description
PL Patent ceased