FI47355C - Menetelmä 1,2alfa-metyleeni-6,7alfa-difluorimetyleeni-20-spiroks-4-een i-3-oni-johdannaisten valmistamiseksi. - Google Patents

Menetelmä 1,2alfa-metyleeni-6,7alfa-difluorimetyleeni-20-spiroks-4-een i-3-oni-johdannaisten valmistamiseksi.

Info

Publication number
FI47355C
FI47355C FI701339A FI133970A FI47355C FI 47355 C FI47355 C FI 47355C FI 701339 A FI701339 A FI 701339A FI 133970 A FI133970 A FI 133970A FI 47355 C FI47355 C FI 47355C
Authority
FI
Finland
Prior art keywords
spirox
7alpha
difluoromethylene
methylene
alpha
Prior art date
Application number
FI701339A
Other languages
English (en)
Swedish (sv)
Other versions
FI47355B (fi
Inventor
Arth
Rasmusson
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI47355B publication Critical patent/FI47355B/fi
Application granted granted Critical
Publication of FI47355C publication Critical patent/FI47355C/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI701339A 1969-05-14 1970-05-13 Menetelmä 1,2alfa-metyleeni-6,7alfa-difluorimetyleeni-20-spiroks-4-een i-3-oni-johdannaisten valmistamiseksi. FI47355C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82467269A 1969-05-14 1969-05-14
US2118370A 1970-03-19 1970-03-19

Publications (2)

Publication Number Publication Date
FI47355B FI47355B (fi) 1973-07-31
FI47355C true FI47355C (fi) 1973-11-12

Family

ID=26694377

Family Applications (2)

Application Number Title Priority Date Filing Date
FI701339A FI47355C (fi) 1969-05-14 1970-05-13 Menetelmä 1,2alfa-metyleeni-6,7alfa-difluorimetyleeni-20-spiroks-4-een i-3-oni-johdannaisten valmistamiseksi.
FI722993A FI47885C (fi) 1969-05-14 1972-10-27 Menetelmä 1,2 alfa-metyleeni-6,7 alfa-difluorimetyleeni-20-spiroks-4-e eni-3-onin valmistamiseksi

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI722993A FI47885C (fi) 1969-05-14 1972-10-27 Menetelmä 1,2 alfa-metyleeni-6,7 alfa-difluorimetyleeni-20-spiroks-4-e eni-3-onin valmistamiseksi

Country Status (17)

Country Link
JP (1) JPS532865B1 (fi)
AR (1) AR192305A1 (fi)
BE (1) BE750330A (fi)
CA (1) CA926385A (fi)
CH (2) CH547792A (fi)
CS (2) CS151551B2 (fi)
DE (1) DE2023450C3 (fi)
DK (3) DK126992B (fi)
FI (2) FI47355C (fi)
FR (1) FR2051526B1 (fi)
GB (1) GB1265444A (fi)
IE (1) IE34194B1 (fi)
IL (1) IL34431A (fi)
NL (1) NL168844C (fi)
NO (1) NO131131C (fi)
SE (2) SE386904B (fi)
YU (1) YU34052B (fi)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes

Also Published As

Publication number Publication date
FI47885C (fi) 1974-04-10
IL34431A0 (en) 1970-07-19
FI47885B (fi) 1974-01-02
IE34194L (en) 1970-11-14
DK126992B (da) 1973-09-10
DE2023450A1 (de) 1971-01-14
FI47355B (fi) 1973-07-31
NL168844C (nl) 1982-05-17
IE34194B1 (en) 1975-03-05
DK127505B (da) 1973-11-19
CH547785A (de) 1974-04-11
SE386904B (sv) 1976-08-23
DE2023450C3 (de) 1979-05-31
BE750330A (fr) 1970-11-13
CS151551B2 (fi) 1973-10-19
JPS532865B1 (fi) 1978-02-01
DK127880C (da) 1974-06-10
CH547792A (de) 1974-04-11
NL168844B (nl) 1981-12-16
FR2051526A1 (fi) 1971-04-09
DK127880B (fi) 1974-01-28
NL7006474A (fi) 1970-11-17
NO131131B (fi) 1974-12-30
YU117670A (en) 1978-05-15
GB1265444A (fi) 1972-03-01
SE366305B (fi) 1974-04-22
DE2023450B2 (de) 1978-10-05
NO131131C (fi) 1975-04-09
YU34052B (en) 1978-10-31
AR192305A1 (es) 1973-02-14
CA926385A (en) 1973-05-15
IL34431A (en) 1974-03-14
FR2051526B1 (fi) 1974-04-12
CS151552B2 (fi) 1973-10-19

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