SE386904B - Forfarande for framstellning av 3-oxigenerad 1,2alfa-metylen-6,7alfa-di-fluormetylen-20-spiroxa-4-en-21-on samt estrar derav - Google Patents

Forfarande for framstellning av 3-oxigenerad 1,2alfa-metylen-6,7alfa-di-fluormetylen-20-spiroxa-4-en-21-on samt estrar derav

Info

Publication number
SE386904B
SE386904B SE7303114A SE311473A SE386904B SE 386904 B SE386904 B SE 386904B SE 7303114 A SE7303114 A SE 7303114A SE 311473 A SE311473 A SE 311473A SE 386904 B SE386904 B SE 386904B
Authority
SE
Sweden
Prior art keywords
estrars
oxygened
2alfa
7alfa
spiroxa
Prior art date
Application number
SE7303114A
Other languages
English (en)
Swedish (sv)
Inventor
G E Arth
G H Rasmusson
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE386904B publication Critical patent/SE386904B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7303114A 1969-05-14 1970-05-13 Forfarande for framstellning av 3-oxigenerad 1,2alfa-metylen-6,7alfa-di-fluormetylen-20-spiroxa-4-en-21-on samt estrar derav SE386904B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82467269A 1969-05-14 1969-05-14
US2118370A 1970-03-19 1970-03-19

Publications (1)

Publication Number Publication Date
SE386904B true SE386904B (sv) 1976-08-23

Family

ID=26694377

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7303114A SE386904B (sv) 1969-05-14 1970-05-13 Forfarande for framstellning av 3-oxigenerad 1,2alfa-metylen-6,7alfa-di-fluormetylen-20-spiroxa-4-en-21-on samt estrar derav
SE06534/70A SE366305B (xx) 1969-05-14 1970-05-13

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE06534/70A SE366305B (xx) 1969-05-14 1970-05-13

Country Status (17)

Country Link
JP (1) JPS532865B1 (xx)
AR (1) AR192305A1 (xx)
BE (1) BE750330A (xx)
CA (1) CA926385A (xx)
CH (2) CH547792A (xx)
CS (2) CS151551B2 (xx)
DE (1) DE2023450C3 (xx)
DK (3) DK126992B (xx)
FI (2) FI47355C (xx)
FR (1) FR2051526B1 (xx)
GB (1) GB1265444A (xx)
IE (1) IE34194B1 (xx)
IL (1) IL34431A (xx)
NL (1) NL168844C (xx)
NO (1) NO131131C (xx)
SE (2) SE386904B (xx)
YU (1) YU34052B (xx)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes

Also Published As

Publication number Publication date
DE2023450B2 (de) 1978-10-05
IE34194L (en) 1970-11-14
JPS532865B1 (xx) 1978-02-01
CA926385A (en) 1973-05-15
FI47355B (xx) 1973-07-31
GB1265444A (xx) 1972-03-01
DE2023450A1 (de) 1971-01-14
DK127880B (xx) 1974-01-28
SE366305B (xx) 1974-04-22
NL168844B (nl) 1981-12-16
NL168844C (nl) 1982-05-17
BE750330A (fr) 1970-11-13
FI47885B (xx) 1974-01-02
IL34431A0 (en) 1970-07-19
DE2023450C3 (de) 1979-05-31
AR192305A1 (es) 1973-02-14
DK127880C (da) 1974-06-10
CS151551B2 (xx) 1973-10-19
CH547785A (de) 1974-04-11
DK126992B (da) 1973-09-10
YU117670A (en) 1978-05-15
FR2051526B1 (xx) 1974-04-12
YU34052B (en) 1978-10-31
NO131131B (xx) 1974-12-30
FI47355C (fi) 1973-11-12
NO131131C (xx) 1975-04-09
CS151552B2 (xx) 1973-10-19
NL7006474A (xx) 1970-11-17
DK127505B (da) 1973-11-19
FR2051526A1 (xx) 1971-04-09
FI47885C (fi) 1974-04-10
IL34431A (en) 1974-03-14
IE34194B1 (en) 1975-03-05
CH547792A (de) 1974-04-11

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