CH533598A - Procédé de purification du méthylester de l'a-L-aspartyl-L-phénylalanine - Google Patents
Procédé de purification du méthylester de l'a-L-aspartyl-L-phénylalanineInfo
- Publication number
- CH533598A CH533598A CH1549971A CH1549971A CH533598A CH 533598 A CH533598 A CH 533598A CH 1549971 A CH1549971 A CH 1549971A CH 1549971 A CH1549971 A CH 1549971A CH 533598 A CH533598 A CH 533598A
- Authority
- CH
- Switzerland
- Prior art keywords
- aspartyl
- methyl ester
- purification process
- phenylalanine methyl
- ester purification
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/801—Peptide sweetners
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP45094076A JPS4941425B1 (fr) | 1970-10-26 | 1970-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH533598A true CH533598A (fr) | 1973-02-15 |
Family
ID=14100388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1549971A CH533598A (fr) | 1970-10-26 | 1971-10-25 | Procédé de purification du méthylester de l'a-L-aspartyl-L-phénylalanine |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3798207A (fr) |
| JP (1) | JPS4941425B1 (fr) |
| CA (1) | CA974230A (fr) |
| CH (1) | CH533598A (fr) |
| DE (1) | DE2152111C3 (fr) |
| FR (1) | FR2113279A5 (fr) |
| GB (1) | GB1326473A (fr) |
| NL (1) | NL175911C (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5235660B2 (fr) * | 1972-05-25 | 1977-09-10 | ||
| US4173562A (en) * | 1976-12-27 | 1979-11-06 | Monsanto Company | Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester |
| JPS6049199B2 (ja) * | 1979-04-10 | 1985-10-31 | 東ソー株式会社 | α−Ｌ−アスパルチル−Ｌ−フエニルアラニン低級アルキルエステルの精製法 |
| US4238392A (en) * | 1979-10-29 | 1980-12-09 | Pfizer Inc. | Purification of L-aspartyl-L-phenylalanine alkyl esters |
| JPS58177952A (ja) * | 1982-04-12 | 1983-10-18 | Ajinomoto Co Inc | Ｌ−α−アスパルチル−Ｌ−フエニルアラニンメチルエステルの晶析法 |
| JPS58185545A (ja) * | 1982-04-22 | 1983-10-29 | Ajinomoto Co Inc | α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法 |
| JPS59219258A (ja) * | 1983-05-28 | 1984-12-10 | Ajinomoto Co Inc | α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法 |
| US4618695A (en) * | 1983-06-02 | 1986-10-21 | Ajinomoto Co., Inc. | Method of preparing methyl ester and its hydrochloride |
| US5225587A (en) * | 1985-07-12 | 1993-07-06 | Ajinomoto Co., Inc. | Method of producing α-L-aspartyl-L-phenylalanine methyl ester hydrochloride |
| US4677220A (en) * | 1985-10-31 | 1987-06-30 | Monsanto Company | Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester |
| JPH0657719B2 (ja) * | 1986-06-03 | 1994-08-03 | 味の素株式会社 | α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの回収方法 |
| US5283357A (en) * | 1988-03-14 | 1994-02-01 | Mitsui Toatsu Chemicals, Incorporated | Separation method of α-l-aspartyl-l-phenylalanine methyl ester |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3492131A (en) * | 1966-04-18 | 1970-01-27 | Searle & Co | Peptide sweetening agents |
| CA909254A (en) * | 1969-12-30 | 1972-09-05 | Ariyoshi Yasuo | METHOD OF PURIFYING LOWER ALKYL OF .alpha.-L-ASPARTYL-L-PHENYLALANINE |
| FR2077486A1 (fr) * | 1970-01-22 | 1971-10-29 | Rhone Poulenc Sa | |
| JPS5140069B1 (fr) * | 1971-07-09 | 1976-11-01 | ||
| GB1309605A (en) * | 1970-01-31 | 1973-03-14 | Ajinomoto Kk | Process for producing alpha-dipeptide esters of l-aspartic acid |
-
1970
- 1970-10-26 JP JP45094076A patent/JPS4941425B1/ja active Pending
-
1971
- 1971-10-19 DE DE2152111A patent/DE2152111C3/de not_active Expired
- 1971-10-21 NL NLAANVRAGE7114488,A patent/NL175911C/xx not_active IP Right Cessation
- 1971-10-21 CA CA125,808A patent/CA974230A/en not_active Expired
- 1971-10-22 GB GB4929971A patent/GB1326473A/en not_active Expired
- 1971-10-25 CH CH1549971A patent/CH533598A/fr not_active IP Right Cessation
- 1971-10-26 US US00192671A patent/US3798207A/en not_active Expired - Lifetime
- 1971-10-26 FR FR7138486A patent/FR2113279A5/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2152111A1 (de) | 1972-04-27 |
| DE2152111B2 (de) | 1979-12-20 |
| FR2113279A5 (fr) | 1972-06-23 |
| NL175911B (nl) | 1984-08-16 |
| JPS4941425B1 (fr) | 1974-11-08 |
| US3798207A (en) | 1974-03-19 |
| NL7114488A (fr) | 1972-04-28 |
| DE2152111C3 (de) | 1980-08-28 |
| NL175911C (nl) | 1985-01-16 |
| GB1326473A (en) | 1973-08-15 |
| CA974230A (en) | 1975-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |