CA974230A - METHOD OF PURIFYING .alpha.-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER - Google Patents

METHOD OF PURIFYING .alpha.-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER

Info

Publication number
CA974230A
CA974230A CA125,808A CA125808A CA974230A CA 974230 A CA974230 A CA 974230A CA 125808 A CA125808 A CA 125808A CA 974230 A CA974230 A CA 974230A
Authority
CA
Canada
Prior art keywords
aspartyl
purifying
alpha
methyl ester
phenylalanine methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA125,808A
Other languages
English (en)
Other versions
CA125808S (en
Inventor
Naotake Sato
Yohko Koguchi
Yasuo Ariyoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of CA974230A publication Critical patent/CA974230A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
CA125,808A 1970-10-26 1971-10-21 METHOD OF PURIFYING .alpha.-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER Expired CA974230A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP45094076A JPS4941425B1 (fr) 1970-10-26 1970-10-26

Publications (1)

Publication Number Publication Date
CA974230A true CA974230A (en) 1975-09-09

Family

ID=14100388

Family Applications (1)

Application Number Title Priority Date Filing Date
CA125,808A Expired CA974230A (en) 1970-10-26 1971-10-21 METHOD OF PURIFYING .alpha.-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER

Country Status (8)

Country Link
US (1) US3798207A (fr)
JP (1) JPS4941425B1 (fr)
CA (1) CA974230A (fr)
CH (1) CH533598A (fr)
DE (1) DE2152111C3 (fr)
FR (1) FR2113279A5 (fr)
GB (1) GB1326473A (fr)
NL (1) NL175911C (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5235660B2 (fr) * 1972-05-25 1977-09-10
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
JPS6049199B2 (ja) * 1979-04-10 1985-10-31 東ソー株式会社 α−Ｌ−アスパルチル−Ｌ−フエニルアラニン低級アルキルエステルの精製法
US4238392A (en) * 1979-10-29 1980-12-09 Pfizer Inc. Purification of L-aspartyl-L-phenylalanine alkyl esters
JPS58177952A (ja) * 1982-04-12 1983-10-18 Ajinomoto Co Inc Ｌ−α−アスパルチル−Ｌ−フエニルアラニンメチルエステルの晶析法
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
US4618695A (en) * 1983-06-02 1986-10-21 Ajinomoto Co., Inc. Method of preparing methyl ester and its hydrochloride
US5225587A (en) * 1985-07-12 1993-07-06 Ajinomoto Co., Inc. Method of producing α-L-aspartyl-L-phenylalanine methyl ester hydrochloride
US4677220A (en) * 1985-10-31 1987-06-30 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
JPH0657719B2 (ja) * 1986-06-03 1994-08-03 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの回収方法
US5283357A (en) * 1988-03-14 1994-02-01 Mitsui Toatsu Chemicals, Incorporated Separation method of α-l-aspartyl-l-phenylalanine methyl ester

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
CA909254A (en) * 1969-12-30 1972-09-05 Ariyoshi Yasuo METHOD OF PURIFYING LOWER ALKYL OF .alpha.-L-ASPARTYL-L-PHENYLALANINE
FR2077486A1 (fr) * 1970-01-22 1971-10-29 Rhone Poulenc Sa
GB1309605A (en) * 1970-01-31 1973-03-14 Ajinomoto Kk Process for producing alpha-dipeptide esters of l-aspartic acid
JPS5140069B1 (fr) * 1971-07-09 1976-11-01

Also Published As

Publication number Publication date
CH533598A (fr) 1973-02-15
FR2113279A5 (fr) 1972-06-23
NL175911C (nl) 1985-01-16
NL175911B (nl) 1984-08-16
DE2152111C3 (de) 1980-08-28
JPS4941425B1 (fr) 1974-11-08
DE2152111B2 (de) 1979-12-20
NL7114488A (fr) 1972-04-28
US3798207A (en) 1974-03-19
DE2152111A1 (de) 1972-04-27
GB1326473A (en) 1973-08-15

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