CH527224A - Verfahren zur Herstellung eines diastereomeren Salzes einer Antipode der (cis-1,2-Epoxypropyl)-phosphonsäure - Google Patents

Verfahren zur Herstellung eines diastereomeren Salzes einer Antipode der (cis-1,2-Epoxypropyl)-phosphonsäure

Info

Publication number
CH527224A
CH527224A CH1578668A CH1578668A CH527224A CH 527224 A CH527224 A CH 527224A CH 1578668 A CH1578668 A CH 1578668A CH 1578668 A CH1578668 A CH 1578668A CH 527224 A CH527224 A CH 527224A
Authority
CH
Switzerland
Prior art keywords
antipode
epoxypropyl
cis
preparation
phosphonic acid
Prior art date
Application number
CH1578668A
Other languages
German (de)
English (en)
Inventor
Grant Christensen Burton
Joseph Leanza William
Robert Beattie Thomas
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH527224A publication Critical patent/CH527224A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505Phosphonic acids containing oxirane groups; esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/14Esters of phosphoric acids containing P(=O)-halide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/14Esters of phosphoric acids containing P(=O)-halide groups
    • C07F9/1403Esters of phosphoric acids containing P(=O)-halide groups containing the structure Hal-P(=O)-O-unsaturated acyclic group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1578668A 1967-10-30 1968-10-22 Verfahren zur Herstellung eines diastereomeren Salzes einer Antipode der (cis-1,2-Epoxypropyl)-phosphonsäure CH527224A (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67920367A 1967-10-30 1967-10-30
US72944568A 1968-05-15 1968-05-15
US75385868A 1968-08-20 1968-08-20

Publications (1)

Publication Number Publication Date
CH527224A true CH527224A (de) 1972-08-31

Family

ID=27418346

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1578668A CH527224A (de) 1967-10-30 1968-10-22 Verfahren zur Herstellung eines diastereomeren Salzes einer Antipode der (cis-1,2-Epoxypropyl)-phosphonsäure

Country Status (17)

Country Link
BE (1) BE723073A (nl)
CH (1) CH527224A (nl)
DE (1) DE1805681C3 (nl)
DK (1) DK139141B (nl)
ES (1) ES359542A1 (nl)
FI (1) FI51703C (nl)
FR (1) FR1592150A (nl)
GB (1) GB1239989A (nl)
IE (1) IE32997B1 (nl)
IL (1) IL30920A (nl)
IT (1) IT986758B (nl)
LU (1) LU57184A1 (nl)
NL (1) NL6814979A (nl)
NO (1) NO132992C (nl)
OA (1) OA03882A (nl)
RO (1) RO54819A (nl)
SE (1) SE377941B (nl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1161974B (it) * 1978-02-02 1987-03-18 Italchemi Spa Derivti dell acido cis.i 2 epossipropilfosfonico loro procedimento di preparazione e composizioni farmaceutiche che li contengono
DE3906953A1 (de) * 1989-03-04 1990-09-20 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung optisch reiner oxirancarbonsaeuren
CN109369718A (zh) * 2018-12-07 2019-02-22 武汉工程大学 一种左磷右铵盐的制备方法及磷霉素

Also Published As

Publication number Publication date
DE1805681B2 (de) 1974-02-14
RO54819A (nl) 1973-02-17
GB1239989A (en) 1971-07-21
FI51703B (nl) 1976-11-30
FR1592150A (nl) 1970-05-11
IE32997B1 (en) 1974-02-20
NL6814979A (nl) 1969-05-02
NO132992B (nl) 1975-11-10
DE1805681A1 (de) 1969-12-11
BE723073A (nl) 1969-04-29
SE377941B (nl) 1975-08-04
IE32997L (en) 1969-04-30
FI51703C (fi) 1977-03-10
IL30920A (en) 1973-03-30
DK139141C (nl) 1979-05-28
LU57184A1 (nl) 1969-05-16
NO132992C (nl) 1976-02-18
OA03882A (fr) 1975-08-14
IL30920A0 (en) 1968-12-26
IT986758B (it) 1975-01-30
DK139141B (da) 1978-12-27
ES359542A1 (es) 1970-10-16
DE1805681C3 (de) 1974-09-19

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Legal Events

Date Code Title Description
PUE Assignment

Owner name: COMPANIA ESPANOLA DE LA PENICILINA Y ANTIBIOTICOS,

PL Patent ceased