CH523265A - Verfahren zur Herstellung von 1-Phenyl-4-alkyl-3 H-1,4-benzodiazepin-2,5 (1H, 4H)-dionen - Google Patents

Verfahren zur Herstellung von 1-Phenyl-4-alkyl-3 H-1,4-benzodiazepin-2,5 (1H, 4H)-dionen

Info

Publication number
CH523265A
CH523265A CH1742668A CH1742668A CH523265A CH 523265 A CH523265 A CH 523265A CH 1742668 A CH1742668 A CH 1742668A CH 1742668 A CH1742668 A CH 1742668A CH 523265 A CH523265 A CH 523265A
Authority
CH
Switzerland
Prior art keywords
diones
benzodiazepine
phenyl
alkyl
preparation
Prior art date
Application number
CH1742668A
Other languages
German (de)
English (en)
Inventor
Karl-Heinz Dr Weber
Zeile Karl Dr Prof
Peter Dr Danneberg
Rolf Dr Giesemann
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to CH280071A priority Critical patent/CH510035A/de
Publication of CH523265A publication Critical patent/CH523265A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1742668A 1967-11-24 1968-11-22 Verfahren zur Herstellung von 1-Phenyl-4-alkyl-3 H-1,4-benzodiazepin-2,5 (1H, 4H)-dionen CH523265A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH280071A CH510035A (de) 1967-11-24 1968-11-22 Verfahren zur Herstellung von 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-(1H,4H)-dionen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (1)

Publication Number Publication Date
CH523265A true CH523265A (de) 1972-05-31

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1742668A CH523265A (de) 1967-11-24 1968-11-22 Verfahren zur Herstellung von 1-Phenyl-4-alkyl-3 H-1,4-benzodiazepin-2,5 (1H, 4H)-dionen

Country Status (13)

Country Link
AT (1) AT280290B (US06168776-20010102-C00028.png)
BE (1) BE724364A (US06168776-20010102-C00028.png)
BR (1) BR6804236D0 (US06168776-20010102-C00028.png)
CH (1) CH523265A (US06168776-20010102-C00028.png)
DE (1) DE1810423B2 (US06168776-20010102-C00028.png)
DK (1) DK124950B (US06168776-20010102-C00028.png)
ES (2) ES360410A1 (US06168776-20010102-C00028.png)
FR (2) FR1593335A (US06168776-20010102-C00028.png)
GB (1) GB1173540A (US06168776-20010102-C00028.png)
IE (1) IE32504B1 (US06168776-20010102-C00028.png)
IL (1) IL31146A (US06168776-20010102-C00028.png)
NL (1) NL6815755A (US06168776-20010102-C00028.png)
SE (1) SE356979B (US06168776-20010102-C00028.png)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
ATE258439T1 (de) 1999-04-30 2004-02-15 Univ Michigan Verwendung von benzodiazepinen zur behandlung von apoptose-induzierten autoimmunerkrankungen
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7572788B2 (en) 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
JP2008528448A (ja) 2005-01-03 2008-07-31 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 新規化合物に関連する組成物および方法、ならびにその標的
EP1893218A4 (en) 2005-06-01 2011-01-12 Univ Michigan NON-SOLVATED BENZODIAZEPINE PREPARATIONS AND METHODS
CA2628193C (en) 2005-11-01 2012-08-14 The Regents Of The University Of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
WO2007146167A1 (en) 2006-06-09 2007-12-21 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7851465B2 (en) 2007-03-09 2010-12-14 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
MX2009011923A (es) * 2007-05-10 2009-11-18 Amr Technology Inc Tetrahidrobenzo-1,4-diazepinas aril- y heteroaril-sustituidas y uso de las mismas para bloquear reabsorcion de norepinefrina, dopamina y serotonina.
CN101855203B (zh) 2007-09-14 2014-03-19 密执安州立大学董事会 F1f0-atp合成酶抑制剂以及相关的方法
CN101918375A (zh) 2007-11-06 2010-12-15 密歇根大学董事会 在皮肤病症的治疗中有用的苯并二氮杂*酮化合物
AU2009291632B2 (en) 2008-09-11 2013-04-04 The Regents Of The University Of Michigan Aryl guanidine F1F0-ATPase inhibitors and related methods
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
US8673897B2 (en) 2009-09-18 2014-03-18 The Regents Of The University Of Michigan Benzodiazepinone compounds and methods of treatment using same
US9126978B2 (en) 2009-11-17 2015-09-08 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
ES2703752T3 (es) 2009-11-17 2019-03-12 Univ Michigan Regents 1,4-Benzodiazepina-2,5-dionas y compuestos relacionados que presentan propiedades terapéuticas
JP6863742B2 (ja) * 2013-09-11 2021-04-21 ジ・アドミニストレーターズ・オブ・ザ・チューレーン・エデュケーショナル・ファンド 新規アントラニルアミドとその使用

Also Published As

Publication number Publication date
DE1810423B2 (de) 1973-03-22
ES378977A1 (es) 1973-01-16
FR8310M (US06168776-20010102-C00028.png) 1970-11-23
DE1810423C3 (US06168776-20010102-C00028.png) 1973-10-11
IL31146A0 (en) 1969-01-29
IL31146A (en) 1972-04-27
IE32504B1 (en) 1973-08-22
BR6804236D0 (pt) 1973-02-08
GB1173540A (en) 1969-12-10
NL6815755A (US06168776-20010102-C00028.png) 1969-05-28
FR1593335A (US06168776-20010102-C00028.png) 1970-05-25
DK124950B (da) 1972-12-11
IE32504L (en) 1969-05-24
DE1810423A1 (de) 1969-10-09
AT280290B (de) 1970-04-10
BE724364A (US06168776-20010102-C00028.png) 1969-05-22
ES360410A1 (es) 1970-11-01
SE356979B (US06168776-20010102-C00028.png) 1973-06-12

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