CH485855A - Verfahren zur Herstellung eines reinen, hochviskosen Hyaluronsäurepräparates - Google Patents

Verfahren zur Herstellung eines reinen, hochviskosen Hyaluronsäurepräparates

Info

Publication number
CH485855A
CH485855A CH378866A CH378866A CH485855A CH 485855 A CH485855 A CH 485855A CH 378866 A CH378866 A CH 378866A CH 378866 A CH378866 A CH 378866A CH 485855 A CH485855 A CH 485855A
Authority
CH
Switzerland
Prior art keywords
pure
production
hyaluronic acid
highly viscous
acid preparation
Prior art date
Application number
CH378866A
Other languages
English (en)
Inventor
Gerhard Dr Billek
Original Assignee
Etapharm Chem Pharm Lab Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Etapharm Chem Pharm Lab Gmbh filed Critical Etapharm Chem Pharm Lab Gmbh
Publication of CH485855A publication Critical patent/CH485855A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/014—Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH378866A 1965-03-17 1966-03-16 Verfahren zur Herstellung eines reinen, hochviskosen Hyaluronsäurepräparates CH485855A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT240465A AT252264B (de) 1965-03-17 1965-03-17 Verfahren zur Herstellung eines reinen hochviskosen Hyaluronsäurepräparates

Publications (1)

Publication Number Publication Date
CH485855A true CH485855A (de) 1970-02-15

Family

ID=3533724

Family Applications (1)

Application Number Title Priority Date Filing Date
CH378866A CH485855A (de) 1965-03-17 1966-03-16 Verfahren zur Herstellung eines reinen, hochviskosen Hyaluronsäurepräparates

Country Status (6)

Country Link
US (1) US3396081A (de)
AT (1) AT252264B (de)
CH (1) CH485855A (de)
DE (1) DE1617447B1 (de)
GB (1) GB1088304A (de)
NL (1) NL6603433A (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000079A1 (en) * 1984-06-08 1986-01-03 Pharmacia Ab Gel of crosslinked hyaluronic acid for use as a vitreous humor substitute

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54132217A (en) * 1978-03-31 1979-10-15 Sunooden Kk Treating agent for autonomic disorder
US5166331A (en) * 1983-10-10 1992-11-24 Fidia, S.P.A. Hyaluronics acid fractions, methods for the preparation thereof, and pharmaceutical compositions containing same
IT1212892B (it) * 1983-10-11 1989-11-30 Della Valle Francesco Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica
EP0138572B1 (de) * 1983-10-11 1990-07-25 FIDIA S.p.A. Fraktionen von Hyaluronsäure mit pharmazeutischer Aktivität, Verfahren zu deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US5093487A (en) * 1986-01-06 1992-03-03 Mobay Corporation Low viscosity high molecular weight filter sterilizable hyaluronic acid
US5316926A (en) * 1983-11-25 1994-05-31 Miles Inc. Method for the microbiological production of non-antigenic hyaluronic acid
NO160722C (no) * 1983-11-25 1989-05-24 Miles Inc Fremgangsmaate for fremstilling av ultraren hyaluronsyre.
NO161573C (no) * 1983-11-25 1989-08-30 Miles Inc Fremgangsmaate til fremstilling av hyaluronsyre.
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US5099013A (en) * 1985-03-12 1992-03-24 Biomatrix, Inc, Hylan preparation and method of recovery thereof from animal tissues
US4713448A (en) * 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
SE8501723L (sv) * 1985-04-09 1986-10-10 Pharmacia Ab Preparation att anvendas vid behandling av ledinflammation
AU593556B2 (en) * 1985-05-09 1990-02-15 David Cullis-Hill High purity hyaluronic acid from synovial fluid
US5079236A (en) * 1987-05-27 1992-01-07 Hyal Pharmaceutical Corporation Pure, sterile, pyrogen-free hyaluronic acid formulations their methods of preparation and methods of use
GB2228736A (en) * 1989-02-10 1990-09-05 Sterivet Lab Ltd Cosmetic formulation
JPH02215707A (ja) * 1989-02-15 1990-08-28 Chisso Corp 皮膚化粧料
US5990096A (en) * 1990-09-18 1999-11-23 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5824658A (en) * 1990-09-18 1998-10-20 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
US5910489A (en) * 1990-09-18 1999-06-08 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
CA2061703C (en) * 1992-02-20 2002-07-02 Rudolf E. Falk Formulations containing hyaluronic acid
IT1247175B (it) * 1991-04-19 1994-12-12 Fidia Spa Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico.
US5234914A (en) * 1991-06-11 1993-08-10 Patent Biopharmaceutics, Inc. Methods of treating hemorrhoids and anorecial disease
US5792753A (en) * 1991-07-03 1998-08-11 Hyal Pharmaceutical Corporation Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs
US5977088A (en) * 1991-07-03 1999-11-02 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US6103704A (en) * 1991-07-03 2000-08-15 Hyal Pharmaceutical Corporation Therapeutic methods using hyaluronic acid
US6218373B1 (en) 1992-02-20 2001-04-17 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5767106A (en) * 1992-02-21 1998-06-16 Hyal Pharmaceutical Corporation Treatment of disease and conditions associated with macrophage infiltration
US5550112A (en) * 1992-12-30 1996-08-27 Patent Biopharmaceutics, Inc. Hyaluronic acid-urea pharmaceutical compositions and uses
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
EP1706095B1 (de) 2004-01-20 2008-12-24 Allergan, Inc. Zusammensetzungen für die lokalisierte therapie des auges, vorzugsweise enthaltend triamcinolon-acetonid und hyaluronsäure
US8119154B2 (en) 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US8673341B2 (en) 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US8147865B2 (en) * 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
WO2008094910A2 (en) 2007-01-30 2008-08-07 Cypress Pharmaceutical, Inc. Hyaluronate compositions
US9579341B2 (en) 2007-05-16 2017-02-28 Johnson & Johnson Consumer Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
US8609634B2 (en) 2007-05-16 2013-12-17 Mcneil-Ppc, Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
US8624077B2 (en) 2008-10-02 2014-01-07 L.R.R.&D. Ltd. Interface layer wound dressing
US20100247606A1 (en) * 2009-03-25 2010-09-30 Allergan, Inc. Intraocular sustained release drug delivery systems and methods for treating ocular conditions
IT201700008651A1 (it) 2017-01-26 2018-07-26 Beauty System Pharma Ltd Acido ialuronico reticolato con agenti reticolanti di tipo naturale o semisintetico
US11129862B2 (en) 2017-08-30 2021-09-28 Johnson & Johnson Consumer Inc. Ophthalmic compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662076A (en) * 1948-02-03 1953-12-08 Searle & Co Hyaluronidase inhibitors and the production thereof
US2599172A (en) * 1948-11-29 1952-06-03 Searle & Co Sulfuric acid esters of hyaluronic acid and processes for the production thereof
US3020204A (en) * 1960-05-11 1962-02-06 American Cyanamid Co Process for preparing augmentative intrinsic factor concentrate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000079A1 (en) * 1984-06-08 1986-01-03 Pharmacia Ab Gel of crosslinked hyaluronic acid for use as a vitreous humor substitute

Also Published As

Publication number Publication date
NL6603433A (de) 1966-09-19
DE1617447B1 (de) 1970-09-24
GB1088304A (en) 1967-10-25
US3396081A (en) 1968-08-06
AT252264B (de) 1967-02-10

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