CH107202A - Process for the preparation of a unilaterally acylated derivative of ethylene diamine. - Google Patents

Process for the preparation of a unilaterally acylated derivative of ethylene diamine.

Info

Publication number
CH107202A
CH107202A CH107202DA CH107202A CH 107202 A CH107202 A CH 107202A CH 107202D A CH107202D A CH 107202DA CH 107202 A CH107202 A CH 107202A
Authority
CH
Switzerland
Prior art keywords
preparation
unilaterally
acylated derivative
ethylene diamine
thick
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH107202A publication Critical patent/CH107202A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

  Verfahren zur Darstellung eines einseitig     acylierten    Derivates des     Äthylendiamins.       Es wurde gefunden, dass man zu einem  einseitig     acylierten    Derivat des     Äthylendi-          amins    gelangen kann, indem man     as.        Diäthyl-          äthylendiamin    mit     -einer    das Radikal der  Ölsäure enthaltenden     Verbindung,    wie z. B.

    Ölsäure, -     Ölsäurehalogeniden        bezw.        -estern     oder     Ölsäureanhydrid    in üblicher Weise be  handelt.  



  Das     Oleyldiäthyläthylendiamid    stellt ein  dickes, nicht destillierbares 01 dar, das in  Wasser unlöslich, in organischen Lösungs  mitteln löslich ist. Es bildet mit     Säuren     wasserlösliche Salze, von denen zum Beispiel  das Chlorhydrat,     Silicofluorid,        Citrat,        Lactat.          Benzoat,        p-Chlorbenzoat,        Salicylat    dicke 01e  darstellen. Die neue Verbindung soll ent  weder als solche oder in Form ihrer Salze  zu technischen und therapeutischen Zwecken  Verwendung finden.

      <I>Beispiel:</I>    282 Teile Ölsäure und 116 Teile     as.        Di-          äthyläthylendiamin    werden zusammen zehn  Stunden entweder offen oder im     -eschlosse-          nen    Gefäss auf 200 bis 220   erhitzt. Das Re  aktionsprodukt wird im Vakuum auf 100    erhitzt, wobei das gebildete Wasser     abdestil-          liert.    Das zurückbleibende     Oleyldiäthyl-          äthylendiamid    kann ohne weitere     Reinigung     verwendet werden.



  Process for the preparation of a unilaterally acylated derivative of ethylene diamine. It has been found that a unilaterally acylated derivative of ethylenediamine can be obtained by using as. Diethyl ethylenediamine with a compound containing the radical of oleic acid, such as. B.

    Oleic acid, oleic acid halides respectively. esters or oleic anhydride in the usual way.



  The oleyl diethyl ethylenediamide is a thick, non-distillable oil that is insoluble in water and soluble in organic solvents. It forms water-soluble salts with acids, of which, for example, the chlorohydrate, silicofluoride, citrate, lactate. Benzoate, p-chlorobenzoate, salicylate represent thick 01e. The new compound is intended to be used either as such or in the form of its salts for technical and therapeutic purposes.

      <I> Example: </I> 282 parts of oleic acid and 116 parts of as. Diethylethylenediamine are heated to 200 to 220 together for ten hours either open or in the closed vessel. The reaction product is heated to 100 in vacuo, the water formed being distilled off. The remaining oleyl diethyl ethylenediamide can be used without further purification.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung eines einseitig acylierten Derivates des Äthylendiamins, da durch gekennzeichnet, dass man as. Diäthyl- äthylendiamin mit einer das Radikal der Öl säure enthaltenden Verbindung behandelt. Das Oleyldiäthyläthylendiamid stellt ein dickes, nicht destillierbares Öl dar, das in Wasser unlöslich, in organischen Lösungs mitteln löslich ist. Claim: Process for the preparation of a one-sided acylated derivative of ethylenediamine, characterized in that as. Diethyl ethylenediamine is treated with a compound containing the radical of oleic acid. The oleyl diethyl ethylenediamide is a thick, non-distillable oil that is insoluble in water and soluble in organic solvents. Es bildet mit Säuren wasserlösliche Salze, von denen zum Beispiel das Chlorhydrat, Silicofluorid, Citrat, Lactat, Benzoat, p-Chlorbenzoat, Salicylat dicke 01e darstellen. Die neue Verbindung soll ent weder als solche oder in Form ihrer Salze zu technischen und therapeutischen Zwecken Verwendung finden. It forms water-soluble salts with acids, of which, for example, the chlorohydrate, silicofluoride, citrate, lactate, benzoate, p-chlorobenzoate, salicylate are thick 01e. The new compound is intended to be used either as such or in the form of its salts for technical and therapeutic purposes.
CH107202D 1923-07-17 1923-07-17 Process for the preparation of a unilaterally acylated derivative of ethylene diamine. CH107202A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH107202T 1923-07-17

Publications (1)

Publication Number Publication Date
CH107202A true CH107202A (en) 1924-10-01

Family

ID=4366109

Family Applications (1)

Application Number Title Priority Date Filing Date
CH107202D CH107202A (en) 1923-07-17 1923-07-17 Process for the preparation of a unilaterally acylated derivative of ethylene diamine.

Country Status (1)

Country Link
CH (1) CH107202A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1098001B (en) * 1957-09-12 1961-01-26 Knoll Ag Process for the preparation of N- (Diaethylaminoalkyl) -salicylamiden

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1098001B (en) * 1957-09-12 1961-01-26 Knoll Ag Process for the preparation of N- (Diaethylaminoalkyl) -salicylamiden

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