CA999000A - Process for new benzodiazepines and intermediates - Google Patents

Process for new benzodiazepines and intermediates

Info

Publication number
CA999000A
CA999000A CA190,079A CA190079A CA999000A CA 999000 A CA999000 A CA 999000A CA 190079 A CA190079 A CA 190079A CA 999000 A CA999000 A CA 999000A
Authority
CA
Canada
Prior art keywords
intermediates
benzodiazepines
new
new benzodiazepines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA190,079A
Other languages
English (en)
Other versions
CA190079S (en
Inventor
Jackson B. Hester (Jr.)
Martin Gall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to CA247,317A priority Critical patent/CA1001622A/en
Application granted granted Critical
Publication of CA999000A publication Critical patent/CA999000A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA190,079A 1973-02-14 1974-01-14 Process for new benzodiazepines and intermediates Expired CA999000A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA247,317A CA1001622A (en) 1973-02-14 1976-03-05 Process for new benzodiazepines and intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33237773A 1973-02-14 1973-02-14

Publications (1)

Publication Number Publication Date
CA999000A true CA999000A (en) 1976-10-26

Family

ID=23297958

Family Applications (1)

Application Number Title Priority Date Filing Date
CA190,079A Expired CA999000A (en) 1973-02-14 1974-01-14 Process for new benzodiazepines and intermediates

Country Status (16)

Country Link
JP (1) JPS49110699A (en:Method)
AU (1) AU471038B2 (en:Method)
BE (1) BE811025A (en:Method)
CA (1) CA999000A (en:Method)
CH (2) CH587263A5 (en:Method)
DE (1) DE2402363A1 (en:Method)
DK (1) DK140803B (en:Method)
ES (2) ES422941A1 (en:Method)
FR (1) FR2217335B1 (en:Method)
GB (3) GB1454683A (en:Method)
HU (1) HU168136B (en:Method)
IL (3) IL49503A (en:Method)
NL (1) NL7400958A (en:Method)
PH (2) PH10784A (en:Method)
SE (2) SE423546B (en:Method)
ZA (1) ZA74466B (en:Method)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709898A (en) * 1971-02-09 1973-01-09 Upjohn Co Process for the production of triazolobenzodiazepines and intermediates

Also Published As

Publication number Publication date
SE8107017L (sv) 1981-11-25
IL44068A (en) 1977-05-31
ZA74466B (en) 1974-12-24
AU471038B2 (en) 1976-04-08
SE435285B (sv) 1984-09-17
CH587263A5 (en:Method) 1977-04-29
DK140803C (en:Method) 1980-04-21
GB1454682A (en) 1976-11-03
DE2402363A1 (de) 1974-08-22
AU6478674A (en) 1975-07-24
PH10784A (en) 1977-09-06
IL44068A0 (en) 1974-05-16
CH586704A5 (en:Method) 1977-04-15
DK140803B (da) 1979-11-19
IL49503A (en) 1977-05-31
ES422941A1 (es) 1976-09-16
HU168136B (en:Method) 1976-02-28
GB1454683A (en) 1976-11-03
IL49503A0 (en) 1976-06-30
PH11789A (en) 1978-07-05
ES445860A1 (es) 1977-05-01
GB1454684A (en) 1976-11-03
BE811025A (fr) 1974-08-14
FR2217335B1 (en:Method) 1977-06-10
NL7400958A (en:Method) 1974-08-16
JPS49110699A (en:Method) 1974-10-22
SE423546B (sv) 1982-05-10
FR2217335A1 (en:Method) 1974-09-06

Similar Documents

Publication Publication Date Title
CA1018299A (en) Process for polymerizing -olefines
AU475436B2 (en) Catalyst and process for making same
CA1002303A (en) Method of making printing discs
CA990152A (en) Asbestos-cement product and process
CA1025455A (en) N-phenylpyrroies and process for their manufacture
CA1018328A (en) Gas-preparation process
AU474992B2 (en) Reduction process
CA1035774A (en) Formylation process
CA1001622A (en) Process for new benzodiazepines and intermediates
AU471038B2 (en) Process for benzodiazepines and intermediates
CA1022546A (en) P-glu-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2 p-glu-d-phe-trp-ser-tyr-d-leu-leu-arg-pro-gly-nh2 and intermediates
AU496440B2 (en) New oxoalkylpyridines and process for their manufacture
AU488611B2 (en) Continuous process
AU489554B2 (en) Ap-glycoproteins and process for isolating them
AU478312B2 (en) New triazolobenzodiazepines and process for their preparation
AU6572574A (en) New oxoalkylpyridines and process for their manufacture
CA1015354A (en) Disteroidyl-ethers and process
AU481190B2 (en) Disteroidyl-ethers and process
CA1002941A (en) Disteroidyl-ethers and process
AU478202B2 (en) Disteroidyl-ethers and process
AU480416B2 (en) Environmental chamber and process for use
AU479547B2 (en) New pyrazolodia zocine compounds and method for their production
AU7235574A (en) Continuous process
AU495232B2 (en) Biochemical process
AU488567B2 (en) Porous products and process therefor