CA997760A - Method of synthesis of pteridines - Google Patents

Method of synthesis of pteridines

Info

Publication number
CA997760A
CA997760A CA119,142A CA119142A CA997760A CA 997760 A CA997760 A CA 997760A CA 119142 A CA119142 A CA 119142A CA 997760 A CA997760 A CA 997760A
Authority
CA
Canada
Prior art keywords
pteridines
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA119,142A
Other languages
English (en)
Other versions
CA119142S (en
Inventor
Saieba Al-Hassan
Adrian C.W. Curran
Hamish C.S. Wood
Alexander Stuart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to CA204,779A priority Critical patent/CA1008085A/en
Application granted granted Critical
Publication of CA997760A publication Critical patent/CA997760A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA119,142A 1970-07-27 1971-07-26 Method of synthesis of pteridines Expired CA997760A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA204,779A CA1008085A (en) 1970-07-27 1974-07-15 Method of synthesis of pteridines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3628970A GB1363064A (en) 1970-07-27 1970-07-27 Pyrimidine derivatives as intermediates in the synthesis of pteridines

Publications (1)

Publication Number Publication Date
CA997760A true CA997760A (en) 1976-09-28

Family

ID=10386747

Family Applications (1)

Application Number Title Priority Date Filing Date
CA119,142A Expired CA997760A (en) 1970-07-27 1971-07-26 Method of synthesis of pteridines

Country Status (21)

Country Link
US (1) US3810893A (de)
JP (1) JPS5439397B1 (de)
AT (1) AT311355B (de)
BE (1) BE770577A (de)
CA (1) CA997760A (de)
CH (1) CH569014A5 (de)
CS (1) CS179373B2 (de)
DD (1) DD95386A5 (de)
DE (1) DE2137339C2 (de)
DK (1) DK139388B (de)
ES (1) ES393486A1 (de)
FI (1) FI52090C (de)
FR (1) FR2100955B1 (de)
GB (1) GB1363064A (de)
HU (1) HU165163B (de)
IE (2) IE36470B1 (de)
IL (1) IL37252A (de)
NL (1) NL172240C (de)
PL (1) PL75064B1 (de)
SE (2) SE389116B (de)
ZA (1) ZA714379B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1454165A (en) * 1972-08-01 1976-10-27 Wellcome Found Biologically active compounds and compositions
US4156725A (en) * 1972-08-01 1979-05-29 Burroughs Wellcome Co. Bacteriostatic biologically active compositions
GB1453831A (en) * 1972-08-01 1976-10-27 Wellcome Found Biologically active compounds and compositions
US4036961A (en) * 1972-08-01 1977-07-19 Burroughs Wellcome Co. Pharmaceutical compositions containing pteridines
GB1451043A (en) * 1972-08-01 1976-09-29 Wellcome Found Biologicylly acitve compounds and compositions
US4042589A (en) * 1972-08-01 1977-08-16 Burroughs Wellcome Co. Pteridine compounds
US4073786A (en) * 1973-07-30 1978-02-14 Burroughs Wellcome Co. 2-Amino-4-hydroxy-6-hydroxymethyl-7,7-diethyl-7,8-dihydropteridine and the 7-spirocyclohexyl analogue thereof
US5196533A (en) * 1983-04-11 1993-03-23 South Alabama Medical Science Foundation, Usa Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines
US7375093B2 (en) 2002-07-05 2008-05-20 Intrexon Corporation Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3635978A (en) * 1969-01-28 1972-01-18 Univ Strathclyde Amino pyrimidines

Also Published As

Publication number Publication date
BE770577A (fr) 1972-01-27
NL7110324A (de) 1972-01-31
IE36469B1 (en) 1976-11-10
PL75064B1 (de) 1974-12-31
NL172240B (nl) 1983-03-01
IL37252A0 (en) 1971-10-20
AT311355B (de) 1973-11-12
DD95386A5 (de) 1973-02-05
FR2100955B1 (de) 1974-09-06
FI52090C (fi) 1977-06-10
ES393486A1 (es) 1974-10-01
CS179373B2 (en) 1977-10-31
US3810893A (en) 1974-05-14
IL37252A (en) 1975-02-10
CH569014A5 (de) 1975-11-14
GB1363064A (en) 1974-08-14
DK139388B (da) 1979-02-12
FI52090B (de) 1977-02-28
IE36470B1 (en) 1976-11-10
IE36469L (en) 1972-01-27
SE7509609A0 (sv) 1975-08-29
DE2137339C2 (de) 1984-12-06
HU165163B (de) 1974-06-28
NL172240C (nl) 1983-08-01
SE389116B (sv) 1976-10-25
DE2137339A1 (de) 1972-03-23
JPS5439397B1 (de) 1979-11-27
FR2100955A1 (de) 1972-03-24
ZA714379B (en) 1973-02-28
DK139388C (de) 1979-07-30

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