CA997350A - Amino derivatives of pyrazolopyridine carboxylic acids and esters - Google Patents
Amino derivatives of pyrazolopyridine carboxylic acids and estersInfo
- Publication number
- CA997350A CA997350A CA147,053A CA147053A CA997350A CA 997350 A CA997350 A CA 997350A CA 147053 A CA147053 A CA 147053A CA 997350 A CA997350 A CA 997350A
- Authority
- CA
- Canada
- Prior art keywords
- esters
- carboxylic acids
- amino derivatives
- pyrazolopyridine
- pyrazolopyridine carboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA211,343A CA997352A (en) | 1971-08-05 | 1974-10-15 | Derivatives of pyrazolopyridine carboxylic acids and esters |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16953671A | 1971-08-05 | 1971-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA997350A true CA997350A (en) | 1976-09-21 |
Family
ID=22616112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA147,053A Expired CA997350A (en) | 1971-08-05 | 1972-07-13 | Amino derivatives of pyrazolopyridine carboxylic acids and esters |
Country Status (17)
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3984422A (en) * | 1972-06-16 | 1976-10-05 | E. R. Squibb & Sons, Inc. | Amino derivatives of [4,3-c]pyrazolopyridine carboxylic acids and esters |
| US3835144A (en) * | 1972-06-16 | 1974-09-10 | Squibb & Sons Inc | Amino derivatives of (4,3-c pyrazolopyridine cabroxylic acids and esters |
| US3957782A (en) * | 1974-12-16 | 1976-05-18 | E. R. Squibb & Sons, Inc. | Pyrazolo [3,4-b]pyrazine-5-carboxylic acids, esters, nitriles and amides |
| US3996233A (en) * | 1975-02-10 | 1976-12-07 | E. R. Squibb & Sons, Inc. | Amino derivatives of imidazo[4,5-b]pyridines |
| CA1071207A (en) * | 1975-04-30 | 1980-02-05 | Theodor Denzel | 4-amino derivatives of 2h-pyrazolo (3,4-b) pyridine-5-carboxylic acids and esters |
| US4038283A (en) * | 1975-04-30 | 1977-07-26 | E. R. Squibb & Sons, Inc. | 4-Alkoxy or hydroxy derivatives of 2H-pyrazolo[3,4-b]pyridine-5-carboxylic acids and esters |
| US3985760A (en) * | 1975-09-11 | 1976-10-12 | E. R. Squibb & Sons, Inc. | Amino derivatives of 6-phenylisoxazolo[5,4-b]pyridines |
| JPS531041U (US07579456-20090825-P00002.png) * | 1976-06-22 | 1978-01-07 | ||
| US4364948A (en) * | 1981-09-28 | 1982-12-21 | Ici Americas Inc. | Pyrazolo[3,4-b]pyridine compounds |
| US4511568A (en) * | 1982-05-12 | 1985-04-16 | Ici Americas Inc. | CNS-Depressant pyrazolopyridines |
| US4552883A (en) * | 1982-06-15 | 1985-11-12 | Ici Americas Inc. | Pyrazolo[3,4-b]pyridine carboxylic acid esters and their pharmaceutical use |
| IT1154024B (it) * | 1982-09-22 | 1987-01-21 | Lepetit Spa | Derivati pridinici e procedimento per la loro produzione |
| GB8425104D0 (en) * | 1984-10-04 | 1984-11-07 | Ici America Inc | Amide derivatives |
| JPH0522500Y2 (US07579456-20090825-P00002.png) * | 1984-12-27 | 1993-06-10 | ||
| JPS61113659U (US07579456-20090825-P00002.png) * | 1984-12-28 | 1986-07-18 | ||
| DE3683541D1 (de) | 1985-06-07 | 1992-03-05 | Ici America Inc | Selektionierte difluorverbindungen. |
| JPS62103137U (US07579456-20090825-P00002.png) * | 1985-12-20 | 1987-07-01 | ||
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| JPS63188572U (US07579456-20090825-P00002.png) * | 1987-05-28 | 1988-12-02 | ||
| GB9716161D0 (en) | 1997-08-01 | 1997-10-08 | Zeneca Ltd | Process |
| EP1043998B1 (en) * | 1997-12-13 | 2007-03-07 | Bristol-Myers Squibb Company | USE OF PYRAZOLO [3,4-b] PYRIDINE AS CYCLIN DEPENDANT KINASE INHIBITORS |
| US6326379B1 (en) | 1998-09-16 | 2001-12-04 | Bristol-Myers Squibb Co. | Fused pyridine inhibitors of cGMP phosphodiesterase |
| GB0230045D0 (en) * | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
| ES2331119T3 (es) * | 2002-09-16 | 2009-12-22 | Glaxo Group Limited | Compuestos de pirazolo(3,4-b)piridina, y su uso como inhibidores de fosfodiesterasa. |
| JP2007514704A (ja) * | 2003-12-19 | 2007-06-07 | グラクソ グループ リミテッド | ピラゾロ［３，４−ｂ］ピリジン化合物およびホスホジエステラーゼ阻害剤としてのその使用 |
| EP1735314A1 (en) * | 2004-03-16 | 2006-12-27 | Glaxo Group Limited | Pyrazolo[3,4-b]pyridine compound, and its use as a pde4 inhibitor |
| GB0405937D0 (en) * | 2004-03-16 | 2004-04-21 | Glaxo Group Ltd | Compounds |
| US8389510B2 (en) * | 2005-11-18 | 2013-03-05 | Astrazeneca Ab | Crystalline forms |
| EP2124908A4 (en) * | 2006-12-20 | 2011-04-27 | Astrazeneca Ab | CONNECTIONS AND ITS USE |
| TW200908968A (en) | 2007-05-29 | 2009-03-01 | Sgx Pharmaceuticals Inc | Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators |
| PE20091552A1 (es) * | 2008-02-06 | 2009-10-25 | Glaxo Group Ltd | Farmacoforos duales - antagonistas muscarinicos de pde4 |
| CL2009000249A1 (es) * | 2008-02-06 | 2009-09-11 | Glaxo Group Ltd | Compuestos derivados de pirazolo[3,4-b] piridin-butanodiamida; composicion farmaceutica; y su uso en el tratamiento del asma, enfermedad pulmonar obstructiva cronica, rinitis, dermatitis atopica, psoriasis. |
| AR070564A1 (es) * | 2008-02-06 | 2010-04-21 | Glaxo Group Ltd | Derivados de 1h-pirazolo[3,4-b]piridin-5-ilo,inhibidores de fosfodiesterasas pde4 y antagonistas de receptores muscarinicos de acetilcolina(machr), utiles en el tratamiento y/o profilaxis de enfermedades respiratorias y alergicas,y composiciones farmaceuticas que los comprenden |
-
0
- BE BE787249D patent/BE787249A/xx not_active IP Right Cessation
-
1971
- 1971-08-05 US US00169536A patent/US3755340A/en not_active Expired - Lifetime
-
1972
- 1972-07-11 ZA ZA724745A patent/ZA724745B/xx unknown
- 1972-07-13 CA CA147,053A patent/CA997350A/en not_active Expired
- 1972-07-25 IE IE1049/72A patent/IE36600B1/xx unknown
- 1972-07-31 AU AU45146/72A patent/AU462839B2/en not_active Expired
- 1972-08-01 DE DE2237765A patent/DE2237765A1/de not_active Withdrawn
- 1972-08-02 GB GB3615572A patent/GB1402172A/en not_active Expired
- 1972-08-04 CH CH179774A patent/CH549590A/fr not_active IP Right Cessation
- 1972-08-04 FR FR7228285A patent/FR2150737B1/fr not_active Expired
- 1972-08-04 NL NLAANVRAGE7210701,A patent/NL176365C/xx not_active IP Right Cessation
- 1972-08-04 CH CH1161072A patent/CH553798A/fr not_active IP Right Cessation
- 1972-08-04 HU HUSU764A patent/HU164519B/hu unknown
- 1972-08-04 ES ES405553A patent/ES405553A1/es not_active Expired
- 1972-08-04 YU YU2020/72A patent/YU35138B/xx unknown
- 1972-08-04 CH CH179674A patent/CH553800A/fr not_active IP Right Cessation
- 1972-08-05 JP JP7872872A patent/JPS5637237B2/ja not_active Expired
- 1972-08-07 AR AR243467A patent/AR199280A1/es active
-
1973
- 1973-04-19 ES ES413941A patent/ES413941A1/es not_active Expired
- 1973-05-08 AR AR247901A patent/AR199294A1/es active
- 1973-08-22 PH PH14939A patent/PH10047A/en unknown
-
1975
- 1975-07-16 PH PH17388A patent/PH13781A/en unknown
-
1980
- 1980-06-19 JP JP8339780A patent/JPS5622784A/ja active Granted
- 1980-06-19 JP JP55083398A patent/JPS597703B2/ja not_active Expired
Also Published As
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