CA969927A - Process for the acidolysis of nitric acid esters of steroid-21-alcohols - Google Patents
Process for the acidolysis of nitric acid esters of steroid-21-alcoholsInfo
- Publication number
- CA969927A CA969927A CA152,373A CA152373A CA969927A CA 969927 A CA969927 A CA 969927A CA 152373 A CA152373 A CA 152373A CA 969927 A CA969927 A CA 969927A
- Authority
- CA
- Canada
- Prior art keywords
- acidolysis
- steroid
- alcohols
- acid esters
- nitric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI000445 HU163145B (de) | 1971-09-23 | 1971-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA969927A true CA969927A (en) | 1975-06-24 |
Family
ID=11000875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA152,373A Expired CA969927A (en) | 1971-09-23 | 1972-09-22 | Process for the acidolysis of nitric acid esters of steroid-21-alcohols |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5111624B2 (de) |
| AT (1) | AT330375B (de) |
| CA (1) | CA969927A (de) |
| CS (1) | CS164787B2 (de) |
| DD (1) | DD99162A5 (de) |
| DE (1) | DE2246203C3 (de) |
| FR (1) | FR2158823A5 (de) |
| HU (1) | HU163145B (de) |
| NL (1) | NL7212423A (de) |
| PL (1) | PL79455B1 (de) |
| SE (1) | SE385121B (de) |
| SU (1) | SU453833A3 (de) |
| YU (1) | YU35036B (de) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5707984A (en) * | 1995-12-08 | 1998-01-13 | G. D. Searle & Co. | Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs |
| US5792758A (en) * | 1995-12-08 | 1998-08-11 | G. D. Searle & Co. | Steroid nitrite ester derivatives useful as anti-inflammatory drugs |
| US5824669A (en) * | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
-
1971
- 1971-09-23 HU HURI000445 patent/HU163145B/hu unknown
-
1972
- 1972-09-13 NL NL7212423A patent/NL7212423A/xx not_active Application Discontinuation
- 1972-09-13 AT AT783972A patent/AT330375B/de active
- 1972-09-15 DD DD16570272A patent/DD99162A5/xx unknown
- 1972-09-21 SE SE1221372A patent/SE385121B/xx unknown
- 1972-09-21 PL PL15785472A patent/PL79455B1/pl unknown
- 1972-09-21 CS CS644272A patent/CS164787B2/cs unknown
- 1972-09-21 JP JP9505072A patent/JPS5111624B2/ja not_active Expired
- 1972-09-21 YU YU239672A patent/YU35036B/xx unknown
- 1972-09-21 FR FR7233548A patent/FR2158823A5/fr not_active Expired
- 1972-09-22 SU SU1832412A patent/SU453833A3/ru active
- 1972-09-22 DE DE19722246203 patent/DE2246203C3/de not_active Expired
- 1972-09-22 CA CA152,373A patent/CA969927A/en not_active Expired
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5707984A (en) * | 1995-12-08 | 1998-01-13 | G. D. Searle & Co. | Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs |
| US5792758A (en) * | 1995-12-08 | 1998-08-11 | G. D. Searle & Co. | Steroid nitrite ester derivatives useful as anti-inflammatory drugs |
| US5824669A (en) * | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| US6197762B1 (en) | 1996-03-22 | 2001-03-06 | Nitromed, Inc. | Nitrosated and nitrosylated steroids compositions, and methods for treating respiratory disorders |
| USRE37116E1 (en) * | 1996-03-22 | 2001-03-27 | Nitromed, Inc. | Nitrosated and nitrosylated compounds, and compositions and their use for treating respiratory disorders |
| US6579863B1 (en) | 1996-03-22 | 2003-06-17 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| US7160920B2 (en) | 1996-03-22 | 2007-01-09 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| US7345037B2 (en) | 1996-03-22 | 2008-03-18 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
| US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5111624B2 (de) | 1976-04-13 |
| FR2158823A5 (en) | 1973-06-15 |
| DE2246203B2 (de) | 1976-07-08 |
| SE385121B (sv) | 1976-06-08 |
| HU163145B (de) | 1973-06-28 |
| PL79455B1 (en) | 1975-06-30 |
| YU239672A (en) | 1979-12-31 |
| DE2246203C3 (de) | 1982-01-21 |
| AT330375B (de) | 1976-06-25 |
| YU35036B (en) | 1980-06-30 |
| SU453833A3 (de) | 1974-12-15 |
| JPS4839470A (de) | 1973-06-09 |
| ATA783972A (de) | 1975-09-15 |
| DE2246203A1 (de) | 1973-03-29 |
| CS164787B2 (de) | 1975-11-28 |
| NL7212423A (de) | 1973-03-27 |
| DD99162A5 (de) | 1973-07-20 |
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