CA966853A - Intermediates useful in the preparation of synthetic penicillins - Google Patents

Intermediates useful in the preparation of synthetic penicillins

Info

Publication number
CA966853A
CA966853A CA188,034A CA188034A CA966853A CA 966853 A CA966853 A CA 966853A CA 188034 A CA188034 A CA 188034A CA 966853 A CA966853 A CA 966853A
Authority
CA
Canada
Prior art keywords
preparation
intermediates useful
synthetic penicillins
penicillins
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA188,034A
Other versions
CA188034S (en
Inventor
Charles T. Holdrege
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US736608A priority Critical patent/US3479339A/en
Priority to SE6908024A priority patent/SE378598B/xx
Priority to DK313869AA priority patent/DK140100B/en
Priority to GB00895/72A priority patent/GB1282743A/en
Priority to NL6908961A priority patent/NL6908961A/xx
Priority to GB29739/69A priority patent/GB1282742A/en
Priority to JP4582569A priority patent/JPS5516595B1/ja
Priority to DE1929997A priority patent/DE1929997C2/en
Priority to FR6919856A priority patent/FR2010848A1/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Priority to CA188,034A priority patent/CA966853A/en
Application granted granted Critical
Publication of CA966853A publication Critical patent/CA966853A/en
Priority to SE7506488A priority patent/SE7506488L/en
Priority to DK404475A priority patent/DK147181C/en
Priority to DK404575A priority patent/DK404575A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00Derivatives of isocyanic acid
    • C07C265/16Derivatives of isocyanic acid having isocyanate groups acylated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/70Nitro radicals
    • C07D307/71Nitro radicals attached in position 5
    • C07D307/72Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
    • C07D307/73Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by amino or imino, or substituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA188,034A 1968-06-13 1973-12-12 Intermediates useful in the preparation of synthetic penicillins Expired CA966853A (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
US736608A US3479339A (en) 1968-06-13 1968-06-13 6-(alpha-3 - acylureidophenylacetamido)- and 6-(alpha - 3 - acylureidothienylacetamido)-penicillanic acids
SE6908024A SE378598B (en) 1968-06-13 1969-06-06
DK313869AA DK140100B (en) 1968-06-13 1969-06-11 6- (D - (-) - alpha-amino-alpha- (4-hydroxyphenyl) -acetamido) -penicillanic acid or salts thereof for use as intermediates.
GB29739/69A GB1282742A (en) 1968-06-13 1969-06-12 Antibacterial penicillin derivatives
JP4582569A JPS5516595B1 (en) 1968-06-13 1969-06-12
NL6908961A NL6908961A (en) 1968-06-13 1969-06-12
GB00895/72A GB1282743A (en) 1968-06-13 1969-06-12 Antibacterial penicillin derivatives
FR6919856A FR2010848A1 (en) 1968-06-13 1969-06-13 6-alpha-3-acylthioureidophenylacetamido-and 6-alpha-3-acylthioureidoth - ie-nylacetamido-penicillanic acids antibacterial and feed additives
DE1929997A DE1929997C2 (en) 1968-06-13 1969-06-13 Acylureidopenicillins, processes for their preparation and antibacterial agents containing these compounds
CA188,034A CA966853A (en) 1968-06-13 1973-12-12 Intermediates useful in the preparation of synthetic penicillins
SE7506488A SE7506488L (en) 1968-06-13 1975-06-06 INTERMEDIATE
DK404475A DK147181C (en) 1968-06-13 1975-09-10 ANALOGY PROCEDURE FOR THE PREPARATION OF ALFA-UREIDOPENICILLINES
DK404575A DK404575A (en) 1968-06-13 1975-09-10 PROCEDURE FOR THE PREPARATION OF 6- (D - (-) - ALFA-AMINO-ALFA- (4-HYDROXYPHENYL) -ACETAMIDO) -PENICILLANIC ACID OR SALTS thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73657468A 1968-06-13 1968-06-13
US73660868A 1968-06-13 1968-06-13
CA55897 1969-07-02
CA188,034A CA966853A (en) 1968-06-13 1973-12-12 Intermediates useful in the preparation of synthetic penicillins

Publications (1)

Publication Number Publication Date
CA966853A true CA966853A (en) 1975-04-29

Family

ID=27425352

Family Applications (1)

Application Number Title Priority Date Filing Date
CA188,034A Expired CA966853A (en) 1968-06-13 1973-12-12 Intermediates useful in the preparation of synthetic penicillins

Country Status (6)

Country Link
JP (1) JPS5516595B1 (en)
CA (1) CA966853A (en)
DK (1) DK140100B (en)
FR (1) FR2010848A1 (en)
NL (1) NL6908961A (en)
SE (2) SE378598B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1854141B (en) * 2005-04-28 2010-06-30 北京信汇科技有限公司 Production of furo urea penicillin sodium

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR47137E (en) * 1936-02-21 1937-01-18 Lyonnaise Des Machines Textile Improvement in weaving mechanics for looms
GB1061335A (en) * 1965-02-16 1967-03-08 Beecham Group Ltd Penicillins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1854141B (en) * 2005-04-28 2010-06-30 北京信汇科技有限公司 Production of furo urea penicillin sodium

Also Published As

Publication number Publication date
JPS5516595B1 (en) 1980-05-02
SE378598B (en) 1975-09-08
SE7506488L (en) 1975-06-06
DK140100C (en) 1984-08-20
NL6908961A (en) 1969-12-16
DK140100B (en) 1979-06-18
FR2010848A1 (en) 1970-02-20

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