CA966828A - 1.alpha.-HYDROXYCHOLECALCIFEROL AND PROCESS OF MAKING SAME - Google Patents

1.alpha.-HYDROXYCHOLECALCIFEROL AND PROCESS OF MAKING SAME

Info

Publication number
CA966828A
CA966828A CA157,668A CA157668A CA966828A CA 966828 A CA966828 A CA 966828A CA 157668 A CA157668 A CA 157668A CA 966828 A CA966828 A CA 966828A
Authority
CA
Canada
Prior art keywords
hydroxycholecalciferol
alpha
making same
making
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA157,668A
Other languages
English (en)
Other versions
CA157668S (en
Inventor
Hector F. Deluca
Michael F. Holick
Erich J. Semmler
Heinrich K. Schnoes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22757377&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA966828(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Application granted granted Critical
Publication of CA966828A publication Critical patent/CA966828A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/174—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA157,668A 1971-12-02 1972-11-28 1.alpha.-HYDROXYCHOLECALCIFEROL AND PROCESS OF MAKING SAME Expired CA966828A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20430571A 1971-12-02 1971-12-02

Publications (1)

Publication Number Publication Date
CA966828A true CA966828A (en) 1975-04-29

Family

ID=22757377

Family Applications (1)

Application Number Title Priority Date Filing Date
CA157,668A Expired CA966828A (en) 1971-12-02 1972-11-28 1.alpha.-HYDROXYCHOLECALCIFEROL AND PROCESS OF MAKING SAME

Country Status (9)

Country Link
US (1) US3741996A (de)
JP (1) JPS5654315B2 (de)
CA (1) CA966828A (de)
CH (2) CH574455A5 (de)
DE (1) DE2259661C3 (de)
DK (1) DK138419B (de)
FR (1) FR2162113B1 (de)
GB (1) GB1359407A (de)
NL (1) NL159093B (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA74158B (en) * 1973-01-10 1975-03-26 Res Inst Medicine Chem Chemical process
US5472957A (en) * 1973-01-10 1995-12-05 Research Institute For Medicine And Chemistry Chemical compounds and process
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
US4670190A (en) * 1973-01-10 1987-06-02 Hesse Robert H 1-α-hydroxy vitamin D compounds and process for preparing same
US3887545A (en) * 1973-11-12 1975-06-03 Hoffmann La Roche Synthesis of 1{60 -hydroxylated cholesterol derivatives
US3879548A (en) * 1974-01-21 1975-04-22 Wisconsin Alumni Res Found Method of treating milk fever in dairy cattle with 1-alpha-hydroxycholecalciferol
JPS5119752A (en) * 1974-08-07 1976-02-17 Masayuki Ishikawa 1 arufua* 2 arufuaa jihidorokishikorekarushifuerooruno seiho
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4035493A (en) * 1975-06-09 1977-07-12 Wisconsin Alumni Research Foundation Rodenticide
JPS5265262A (en) * 1975-11-27 1977-05-30 Teijin Ltd Synthesis of 1alpha acyloxy-provitamine d compounds
JPS5265261A (en) * 1975-11-27 1977-05-30 Teijin Ltd Synthesis of 1alpha-hyaroxy-provitamine d compounds
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法
JPS53147051A (en) * 1977-05-24 1978-12-21 Teijin Ltd 1alpha-hydroxy-24-dehydro-vitamin d3 and its preparation
IT1106130B (it) * 1977-06-13 1985-11-11 Merck & Co Inc Derivati di 24-deidrovitamina d3 e loro preparazione
US4230700A (en) * 1977-12-07 1980-10-28 The Procter & Gamble Company Methods for inhibiting mobilization of calcium phosphate in animal tissue
US4330537A (en) * 1977-12-07 1982-05-18 The Procter & Gamble Company Compositions for inhibiting mobilization of calcium phosphate in animal tissue
JPS557215A (en) * 1978-06-30 1980-01-19 Teijin Ltd Preparation of active vitamin d3 or its oh-protected derivative and/or its corresponding previtamin d3 or its oh-protected derivative
US4201881A (en) * 1979-03-28 1980-05-06 Wisconsin Alumni Research Foundation 24,24-Difluoro-1α,25-dihydroxycholecalciferol
JPS5626820A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Immunosuppressing agent
JPS5626819A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Preventive for hypoimmunity
IL59221A0 (en) * 1980-01-25 1980-05-30 Yeda Res & Dev Method of improving the shell quality of poultry eggs
US4254045A (en) * 1980-04-21 1981-03-03 Wisconsin Alumni Research Foundation 1α-Hydroxy-2β-fluorocholecalciferol
DE3276167D1 (en) * 1981-11-02 1987-06-04 Res Inst Medicine Chem Intermediates in the synthesis of vitamin d derivatives
DE3590020C2 (de) * 1984-01-30 1995-03-09 Wisconsin Alumni Res Found In der Seitenkette ungesättigte 1-Hydroxyvitamin D-Verbindungen
US5120722A (en) * 1984-02-08 1992-06-09 Hoffmann-La Roche Inc. Trihydroxy-cholecacliferol and trihydroxy-ergocalciferol for treating leukemia
US4588716A (en) * 1984-05-04 1986-05-13 Wisconsin Alumni Research Foundation Method for treating metabolic bone disease in mammals
US5316770A (en) * 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5366736A (en) * 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
AU5185790A (en) * 1989-02-16 1990-09-05 University Of Georgia Research Foundation, Inc., The Treatment of tibial dyschondroplasia
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5763429A (en) * 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6566353B2 (en) * 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
BR9815442A (pt) * 1997-02-13 2001-08-21 Bone Care Int Inc Liberação terapêutica dirigida de compostos de vitamina d
US6087350A (en) * 1997-08-29 2000-07-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of pretreatment chemicals to enhance efficacy of cytotoxic agents
ES2368824T3 (es) * 1998-03-27 2011-11-22 Oregon Health & Science University Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
US20020045606A1 (en) 1999-12-02 2002-04-18 Reddy Satyanarayana G. Esters of vitamin D3 and uses thereof
IL153378A0 (en) * 2000-07-18 2003-07-06 Bone Care Internat Inc STABILIZED 1alpha-HYDROXY VITAMIN D
US7148211B2 (en) 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
BRPI0508333A (pt) 2004-03-01 2007-07-17 Bioxell Spa uso de um composto de vitamina d, método de prevenir e/ou tratar cistite intersticial, formulação farmacêutica, composto de vitamina d, e, kit
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
JP2008519808A (ja) 2004-11-12 2008-06-12 ビオエクセル エスピーエー 膀胱癌治療のためのビタミンｄ誘導体及び抗増殖薬の併用
CN101516210A (zh) * 2006-09-14 2009-08-26 帝斯曼知识产权资产管理有限公司 含有一种或多种维生素d3化合物和一种或多种镁盐的食物补剂组合物
US20110207952A1 (en) * 2010-02-22 2011-08-25 Rafael Avila Cholesterol extraction from algae and preparation of vegan vitamin d3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565924A (en) * 1968-07-01 1971-02-23 Wisconsin Alumni Res Found 25-hydroxycholfcalciferol
US3702810A (en) * 1971-03-02 1972-11-14 Wisconsin Alumni Res Found Photochemical method for preparing 25-hydroxytachysterol3

Also Published As

Publication number Publication date
JPS5654315B2 (de) 1981-12-24
DE2259661C3 (de) 1975-12-18
GB1359407A (en) 1974-07-10
FR2162113B1 (de) 1975-10-31
DK138419B (da) 1978-09-04
US3741996A (en) 1973-06-26
CH574455A5 (de) 1976-04-15
JPS4862750A (de) 1973-09-01
DE2259661A1 (de) 1973-06-07
DE2259661B2 (de) 1975-05-15
FR2162113A1 (de) 1973-07-13
NL159093B (nl) 1979-01-15
DK138419C (de) 1979-02-12
NL7216324A (de) 1973-06-05
CH579042A5 (de) 1976-08-31

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