CA961500A - Process of separating optical, geometric, structural isomers and the compounds used therefor - Google Patents
Process of separating optical, geometric, structural isomers and the compounds used thereforInfo
- Publication number
- CA961500A CA961500A CA136,671A CA136671A CA961500A CA 961500 A CA961500 A CA 961500A CA 136671 A CA136671 A CA 136671A CA 961500 A CA961500 A CA 961500A
- Authority
- CA
- Canada
- Prior art keywords
- geometric
- compounds used
- used therefor
- structural isomers
- separating optical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Braiding, Manufacturing Of Bobbin-Net Or Lace, And Manufacturing Of Nets By Knotting (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT49167/71A IT951631B (it) | 1971-03-18 | 1971-03-18 | Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA961500A true CA961500A (en) | 1975-01-21 |
Family
ID=11269830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA136,671A Expired CA961500A (en) | 1971-03-18 | 1972-03-09 | Process of separating optical, geometric, structural isomers and the compounds used therefor |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3848030A (pl) |
| JP (1) | JPS5547013B1 (pl) |
| AU (1) | AU462431B2 (pl) |
| BE (1) | BE780887A (pl) |
| CA (1) | CA961500A (pl) |
| CH (1) | CH576921A5 (pl) |
| DE (1) | DE2212660C3 (pl) |
| DK (1) | DK139944B (pl) |
| ES (1) | ES400862A1 (pl) |
| FR (1) | FR2129741A5 (pl) |
| GB (1) | GB1360946A (pl) |
| IL (1) | IL38860A (pl) |
| IT (1) | IT951631B (pl) |
| NL (1) | NL7203574A (pl) |
| NO (1) | NO136357C (pl) |
| PH (1) | PH10768A (pl) |
| SE (1) | SE409323B (pl) |
| ZA (1) | ZA721297B (pl) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4143028A (en) * | 1977-12-05 | 1979-03-06 | Ciba-Geigy Corporation | Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions |
| US5288914A (en) * | 1984-08-27 | 1994-02-22 | The Dow Chemical Company | Poly(arylcyclobutenes) |
| NL8403224A (nl) * | 1984-10-24 | 1986-05-16 | Oce Andeno Bv | Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen. |
| DE3940765A1 (de) * | 1989-12-09 | 1991-06-13 | Hoechst Ag | Verfahren zur herstellung reiner cyclischer phosphorsaeurediarylester |
| ES2149357T3 (es) * | 1994-05-16 | 2000-11-01 | Merrell Pharma Inc | Procedimiento y sales diastereomeras utiles para la resolucion optica del acido 4-(4-((hidroxidifenilmetil)-1-piperidinil)-1-hidroxibutil)-alfa,alfa-dimetilbenceno acetico racemico. |
| JP4725757B2 (ja) * | 1999-03-24 | 2011-07-13 | 東ソー株式会社 | ビナフトールリン酸誘導体及びその利用 |
| DE60008807T2 (de) | 1999-03-24 | 2005-01-13 | Tosoh Corp., Shinnanyo | Binaphtol-monophosphorsäurederivate und deren Verwendung |
| ATE320420T1 (de) | 1999-10-22 | 2006-04-15 | Takeda Pharmaceutical | Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver |
| CA2390921A1 (en) * | 1999-11-10 | 2001-05-17 | Hiroyuki Tawada | Process for the production of optically active cyclic enaminone derivative |
| US6391926B2 (en) | 2000-03-13 | 2002-05-21 | Tosoh Corporation | Optically active phosphate derivative |
| EP1411916B1 (en) | 2001-07-09 | 2008-08-27 | Repros Therapeutics Inc. | Methods and materials for the treatment of testosterone deficiency in men |
| WO2004096753A1 (ja) * | 2003-04-25 | 2004-11-11 | Toagosei Co., Ltd. | キラルなブレンステッド酸による不斉合成用触媒および当該触媒を用いた不斉合成方法 |
| US7229557B2 (en) * | 2004-02-04 | 2007-06-12 | Konec, Inc. | Method to separate stereoisomers |
| EP2486032A4 (en) * | 2009-10-09 | 2013-03-27 | Hetero Research Foundation | RACEMATSPALTUNG SUBSTITUTED 2- (2-PYRIDINYLMETHYLSULFINYL) -1H-BENZIMIDAZOLE |
| UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
| JP2015527360A (ja) | 2012-08-21 | 2015-09-17 | レプロス セラピューティクス インコーポレイティド | トランス−クロミフェン製剤およびその使用 |
| CN104994877A (zh) | 2012-11-02 | 2015-10-21 | 利普生物药剂公司 | 用于癌症治疗的反式-克罗米芬 |
| CA2942301A1 (en) * | 2014-03-11 | 2015-09-17 | Repros Therapeutics Inc. | Clomiphene synthesis using a single solvent |
| KR20170040797A (ko) | 2014-07-24 | 2017-04-13 | 아스펜 파크 파마슈티컬스 인코포레이티드 | 시스-클로미펜을 이용하여 안드로겐 박탈 요법 유발된 일과성 열감 및 골 소실을 치료하는 방법 |
| EP3015454A1 (en) * | 2014-10-28 | 2016-05-04 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Stable solid form of trans-Clomiphene citrate |
| EP3015453B1 (en) | 2014-10-28 | 2016-10-12 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Process for the preparation of Clomiphene |
| WO2017182097A1 (en) | 2016-04-22 | 2017-10-26 | F.I.S. - Fabbrica Italiana Sintetici S.P.A. | Process for the preparation of enclomiphene citrate having needle shaped crystal habit. |
| KR20240155974A (ko) | 2017-09-11 | 2024-10-29 | 아토사 테라퓨틱스, 인크. | 엔독시펜을 제조 및 사용하는 방법 |
| FR3082842A1 (fr) * | 2018-06-21 | 2019-12-27 | Veru Inc. | Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci |
| AU2020300624A1 (en) | 2019-07-03 | 2022-02-03 | Atossa Therapeutics, Inc. | Sustained release compositions of endoxifen |
| CA3098552A1 (en) | 2019-11-14 | 2021-05-14 | Apotex Inc. | Processes for the preparation of zuclomiphene and intermediates thereof |
| CA3098725A1 (en) | 2019-11-14 | 2021-05-14 | Apotex Inc. | Zuclpomiphene salts and crystalline forms thereof |
| CA3105944A1 (en) | 2020-01-22 | 2021-07-22 | Apotex Inc. | Crystalline forms of zuclomiphene citrate |
| EP3907213A1 (en) | 2020-05-04 | 2021-11-10 | Pcas | Processes for the production of isomerically pure or enriched cis-clomiphene |
| US11578025B2 (en) | 2020-10-19 | 2023-02-14 | Apotex Inc. | Processes for the preparation of zuclomiphene intermediates |
-
1971
- 1971-03-18 IT IT49167/71A patent/IT951631B/it active
-
1972
- 1972-02-28 ZA ZA721297A patent/ZA721297B/xx unknown
- 1972-02-29 IL IL38860A patent/IL38860A/xx unknown
- 1972-03-03 PH PH13312A patent/PH10768A/en unknown
- 1972-03-03 AU AU39611/72A patent/AU462431B2/en not_active Expired
- 1972-03-09 CA CA136,671A patent/CA961500A/en not_active Expired
- 1972-03-09 GB GB1104172A patent/GB1360946A/en not_active Expired
- 1972-03-10 US US00233793A patent/US3848030A/en not_active Expired - Lifetime
- 1972-03-15 SE SE7203303A patent/SE409323B/xx unknown
- 1972-03-16 DE DE2212660A patent/DE2212660C3/de not_active Expired
- 1972-03-17 NL NL7203574A patent/NL7203574A/xx not_active Application Discontinuation
- 1972-03-17 DK DK127372AA patent/DK139944B/da unknown
- 1972-03-17 ES ES400862A patent/ES400862A1/es not_active Expired
- 1972-03-17 BE BE780887A patent/BE780887A/xx unknown
- 1972-03-17 NO NO880/72A patent/NO136357C/no unknown
- 1972-03-17 FR FR7209350A patent/FR2129741A5/fr not_active Expired
- 1972-03-17 JP JP2661472A patent/JPS5547013B1/ja active Pending
- 1972-03-17 CH CH395572A patent/CH576921A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2212660B2 (de) | 1980-07-10 |
| NL7203574A (pl) | 1972-09-20 |
| NO136357B (pl) | 1977-05-16 |
| SE409323B (sv) | 1979-08-13 |
| AU3961172A (en) | 1973-09-06 |
| JPS5547013B1 (pl) | 1980-11-27 |
| IT951631B (it) | 1973-07-10 |
| DE2212660C3 (de) | 1981-09-24 |
| US3848030A (en) | 1974-11-12 |
| IL38860A (en) | 1975-06-25 |
| FR2129741A5 (pl) | 1972-10-27 |
| CH576921A5 (pl) | 1976-06-30 |
| PH10768A (en) | 1977-09-05 |
| AU462431B2 (en) | 1975-06-09 |
| ZA721297B (en) | 1973-03-28 |
| GB1360946A (en) | 1974-07-24 |
| DK139944C (pl) | 1979-10-22 |
| DE2212660A1 (de) | 1972-09-28 |
| BE780887A (fr) | 1972-07-17 |
| NO136357C (no) | 1977-08-24 |
| DK139944B (da) | 1979-05-21 |
| ES400862A1 (es) | 1976-04-16 |
| IL38860A0 (en) | 1972-04-27 |
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