CA957376A - 4-(4-(.alpha.-HYDROXYBENZYL)PIPERIDINO)-4'-FLUOROBUTYROPHENONE DERIVATIVES - Google Patents

4-(4-(.alpha.-HYDROXYBENZYL)PIPERIDINO)-4'-FLUOROBUTYROPHENONE DERIVATIVES

Info

Publication number
CA957376A
CA957376A CA126,448A CA126448A CA957376A CA 957376 A CA957376 A CA 957376A CA 126448 A CA126448 A CA 126448A CA 957376 A CA957376 A CA 957376A
Authority
CA
Canada
Prior art keywords
fluorobutyrophenone
hydroxybenzyl
piperidino
alpha
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA126,448A
Other languages
English (en)
Other versions
CA126448S (en
Inventor
Albert A. Carr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Ltd Canada
Original Assignee
Richardson Merrell Canada Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Canada Ltd filed Critical Richardson Merrell Canada Ltd
Application granted granted Critical
Publication of CA957376A publication Critical patent/CA957376A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA126,448A 1970-11-27 1971-10-29 4-(4-(.alpha.-HYDROXYBENZYL)PIPERIDINO)-4'-FLUOROBUTYROPHENONE DERIVATIVES Expired CA957376A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9349570A 1970-11-27 1970-11-27

Publications (1)

Publication Number Publication Date
CA957376A true CA957376A (en) 1974-11-05

Family

ID=22239276

Family Applications (1)

Application Number Title Priority Date Filing Date
CA126,448A Expired CA957376A (en) 1970-11-27 1971-10-29 4-(4-(.alpha.-HYDROXYBENZYL)PIPERIDINO)-4'-FLUOROBUTYROPHENONE DERIVATIVES

Country Status (16)

Country Link
JP (1) JPS5623985B2 (nl)
BE (1) BE775593A (nl)
CA (1) CA957376A (nl)
CH (1) CH562215A5 (nl)
DE (1) DE2158136C2 (nl)
DK (1) DK135895B (nl)
ES (1) ES397370A1 (nl)
FR (1) FR2115451B1 (nl)
GB (1) GB1314955A (nl)
IE (1) IE35778B1 (nl)
IL (1) IL38079A (nl)
NL (1) NL175411C (nl)
NO (1) NO135248C (nl)
PH (1) PH9306A (nl)
SE (1) SE369900B (nl)
ZA (1) ZA717147B (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7409245L (nl) * 1973-07-19 1975-01-20 Robins Co Inc A H
US4246268A (en) * 1979-02-09 1981-01-20 Richardson-Merrell Inc. Neuroleptic-4-(naphthylmethyl)piperidine derivatives
IE49998B1 (en) * 1979-08-06 1986-01-22 Merrell Dow Pharma 4-(naphthalenyloxy)piperidine derivatives
US4284636A (en) * 1979-09-04 1981-08-18 Richardson-Merrell Inc. Cinnamoylpiperidinobutyrophenone antipsychotic agents
US4283404A (en) * 1979-09-04 1981-08-11 Richardson-Merrell Inc. Aroylethenylpiperidinobutyrophenone antipsychotic agents
ZA806501B (en) * 1979-10-27 1981-10-28 Richardson Merrell Inc 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents
CA1280421C (en) * 1985-07-02 1991-02-19 Albert A. Carr 1,4-disubstituted piperidinyl derivatives
US4783471A (en) * 1985-07-02 1988-11-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine methanol derivatives and the uses thereof
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
CN101018776A (zh) * 2004-09-13 2007-08-15 拜尔农作物科学股份公司 制备n－(取代的芳基甲基)－4－(二取代的甲基)哌啶和中间体的方法

Also Published As

Publication number Publication date
ZA717147B (en) 1972-07-26
CH562215A5 (nl) 1975-05-30
IL38079A0 (en) 1972-01-27
IE35778B1 (en) 1976-05-26
DE2158136A1 (de) 1972-05-31
JPS5623985B2 (nl) 1981-06-03
FR2115451A1 (nl) 1972-07-07
IL38079A (en) 1974-10-22
SE369900B (nl) 1974-09-23
DK135895B (da) 1977-07-11
NL7116194A (nl) 1972-05-30
DE2158136C2 (de) 1982-11-18
GB1314955A (en) 1973-04-26
IE35778L (en) 1972-05-27
NO135248C (nl) 1977-03-09
NL175411B (nl) 1984-06-01
NO135248B (nl) 1976-11-29
BE775593A (fr) 1972-03-16
ES397370A1 (es) 1974-05-16
NL175411C (nl) 1984-11-01
PH9306A (en) 1975-08-18
DK135895C (nl) 1977-12-12
FR2115451B1 (nl) 1975-02-07

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