CA951319A - Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them - Google Patents

Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them

Info

Publication number
CA951319A
CA951319A CA114,709,A CA114709A CA951319A CA 951319 A CA951319 A CA 951319A CA 114709 A CA114709 A CA 114709A CA 951319 A CA951319 A CA 951319A
Authority
CA
Canada
Prior art keywords
piperazinylalkyl
quinazolone
derivatives
production
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA114,709,A
Other languages
English (en)
Other versions
CA114709S (en
Inventor
Wolfgang Schoetensack
Hermann Amschler
Kurt Klemm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Application granted granted Critical
Publication of CA951319A publication Critical patent/CA951319A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA114,709,A 1970-06-05 1971-06-03 Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them Expired CA951319A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702027645 DE2027645A1 (de) 1970-06-05 1970-06-05 Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CA951319A true CA951319A (en) 1974-07-16

Family

ID=5773104

Family Applications (1)

Application Number Title Priority Date Filing Date
CA114,709,A Expired CA951319A (en) 1970-06-05 1971-06-03 Piperazinylalkyl-quinazolone-(4) derivatives, process for their production and pharmaceutical products containing them

Country Status (10)

Country Link
US (1) US3984555A (sl)
AT (3) AT318615B (sl)
BE (1) BE768137A (sl)
CA (1) CA951319A (sl)
CH (3) CH569732A5 (sl)
DE (1) DE2027645A1 (sl)
FR (1) FR2100726B1 (sl)
GB (1) GB1331522A (sl)
LU (1) LU63267A1 (sl)
NL (1) NL7107695A (sl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US6723727B1 (en) * 1996-12-20 2004-04-20 Hoechst Aktiengesellschaft Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
DE69842109D1 (de) * 1997-08-21 2011-03-10 Shiseido Co Ltd Chinazolin-4-on Derivate, deren Herstellung und deren Verwendung als Haarwuchsmittel oder in äusserlich anzuwendenden Hautpflegemitteln
US6436919B1 (en) 1999-10-01 2002-08-20 Theravance Inc. Local anesthetic compounds
US6667300B2 (en) 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
ATE502941T1 (de) * 2000-04-25 2011-04-15 Icos Corp Hemmer der menschlichen phosphatidyl-inositol-3- kinase delta
AUPR201600A0 (en) * 2000-12-11 2001-01-11 Fujisawa Pharmaceutical Co., Ltd. Quinazolinone derivative
EP2116248A1 (en) 2001-09-05 2009-11-11 Minerva Biotechnologies Corporation Compositions and Methods of Treatment of Cancer
WO2003020280A2 (en) * 2001-09-05 2003-03-13 Minerva Biotechnologies Corporation Compositions and use thereof in the treatment of cancer
JP2005511581A (ja) 2001-11-07 2005-04-28 メルク　エンド　カムパニー　インコーポレーテッド 有糸分裂キネシン阻害剤
AUPS019702A0 (en) * 2002-01-29 2002-02-21 Fujisawa Pharmaceutical Co., Ltd. Condensed heterocyclic compounds
US20040048853A1 (en) * 2002-08-21 2004-03-11 Gustave Bergnes Compounds, compositions, and methods
EP1558260A4 (en) * 2002-11-04 2006-10-25 Nps Pharma Inc CHINAZOLINONE COMPOUNDS AS CALCILYTIC
WO2004111014A1 (en) * 2003-06-06 2004-12-23 Vertex Pharmaceuticals Incorporated Pyrimidine derivatives as modulators of atp-binding cassette transporters
US20050054614A1 (en) * 2003-08-14 2005-03-10 Diacovo Thomas G. Methods of inhibiting leukocyte accumulation
WO2005016348A1 (en) * 2003-08-14 2005-02-24 Icos Corporation Method of inhibiting immune responses stimulated by an endogenous factor
US7932260B2 (en) 2004-05-13 2011-04-26 Icos Corporation Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
EP1755609A1 (en) * 2004-05-25 2007-02-28 Icos Corporation Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
EP1885356A2 (en) * 2005-02-17 2008-02-13 Icos Corporation Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
US8349850B2 (en) * 2006-03-28 2013-01-08 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
ES2674719T3 (es) 2008-11-13 2018-07-03 Gilead Calistoga Llc Terapias para neoplasias hematológicas
EP2411391A1 (en) 2009-03-24 2012-02-01 Gilead Calistoga LLC Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
CN102458410A (zh) * 2009-04-20 2012-05-16 吉联亚·卡利斯托加有限责任公司 治疗实体瘤的方法
CN102647987A (zh) 2009-07-21 2012-08-22 吉里德卡利斯托加公司 使用pi3k抑制剂治疗肝脏障碍
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
CA2832822A1 (en) * 2011-04-10 2012-10-18 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
AR090253A1 (es) 2012-03-05 2014-10-29 Gilead Calistoga Llc Formas polimorficas de (s)-2-(1-(9h-purin-6-ilamino)propil)-5-fluor-3-fenilquinazolin-4(3h)-ona
ES2595240T3 (es) 2012-07-09 2016-12-28 Lupin Limited Derivados de tetrahidroquinazolinona como inhibidores de PARP
MX2016008259A (es) 2013-12-20 2016-10-13 Gilead Calistoga Llc Metodo de proceso para inhibidores de fosfatidilinositol 3-cinasa.
US9708327B2 (en) 2013-12-20 2017-07-18 Gilead Calistoga Llc Polymorphic forms of a hydrochloride salt of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
SG11201609877XA (en) 2014-06-13 2016-12-29 Gilead Sciences Inc Phosphatidylinositol 3-kinase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1249281B (sl) * 1963-05-18

Also Published As

Publication number Publication date
AT318628B (de) 1974-11-11
AT318615B (de) 1974-11-11
FR2100726B1 (sl) 1975-10-10
NL7107695A (sl) 1971-12-07
AT317899B (de) 1974-09-25
GB1331522A (en) 1973-09-26
CH558374A (de) 1975-01-31
FR2100726A1 (sl) 1972-03-24
US3984555A (en) 1976-10-05
CH569732A5 (sl) 1975-11-28
CH557829A (de) 1975-01-15
LU63267A1 (sl) 1972-08-23
DE2027645A1 (de) 1971-12-09
BE768137A (fr) 1971-12-06

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